Heart Cell Coupling and Impulse Propagation in Health and Disease

by De Mello, Walmor C.; Janse, Michiel J.

• ISBN13: 9781402071829
• ISBN10: 1402071825
• Format: Hardcover
• Copyright: 2002-11-01
• Publisher: Kluwer Academic Pub

Summary

Heart Cell Coupling and Impulse Propagation in Health and Disease includes an up-to-date review on how heart cells communicate and impulse propagation under normal as well as under pathological conditions. The complexity of intercellular coupling and impulse propagation is discussed, providing the reader with a broad view of the importance of these processes and how they contribute to the generation of cardiac arrhythmias and heart failure. The different aspects and intricacies of heart cell communication is discussed by different authors, each one an expert in their own field. The present publication will be of interest to cardiologists, electrophysiologists, heart physiologists, cardiac pharmacologists, biophysicists, and cell or molecular biologists.

Table of Contents

Introduction
Walmor C De Mello
The Cardiac Syncytium. An Overview	1	(24)
Walmor C De Mello
Connexin Interacting Proteins	25	(26)
Ralph Barker
Robert G. Gourdie
Cardiovascular Connexins: Molecular Composition and Biochemical Regulation	51	(38)
Eric C. Beyer
Kyung Hwan Seul
Heteromultimeric Gap Junction Channels: A Connection with Cardiac Physiology and Pathology	89	(20)
Alonso P. Moreno
Guoqiang Zhong
Volodya Hayrapetyan
Intercellular Calcium Signaling In The Cardiovascular System	109	(34)
Sylvia O. Suadicani
David Spray
Biophysics of Gap Junction Channels	143	(42)
Richard D. Veenstra
Phosphorylation of Connexin43 and Regulation Of Cardiac Gap Junction	185	(22)
Issei Imanaga
Nobue Hirosawa
Hai Lin
Yasuji Sakamoto
Takashi Matsumura
Ken Mayama
The Sinoatrial Node.Gap Junction Distribution And Impulse Propagation	207	(28)
Mark R. Boyett
Haruo Honjo
Henggui Zhang
Yoshiko Takagishi
Itsuo Kodama
Inward and Outward Currents and Cardiac Discontinuous Conduction	235	(22)
Mary B. Wagner
Ronald W. Joyner
Cellular Electrical Uncoupling During Ischemia	257	(26)
Michiel J. Janse
Hanno L. Tan
Lukas R.C. Dekker
Andre G. Kleber
Cell Coupling and Impulse Propagation In the Failing Heart: The Role of the Renin Angiotensin System	283	(38)
Walmor C. De Mello
Gap Junctions and Connexin Expression in Human Heart Disease	321	(14)
Nicholas J. Severs
Ionic Channels and Fibrillation	335	(26)
Justus M.B. Anumonwo
Omer Berenfeld
Amit Dhamoon
Jose Jalife
Gap Junctions, Cardiac Excitability and Clinical Arrhythmias	361	(100)
Morton F. Arnsdorf
Peter J Lee
Index	461