Hematopoietic Stem Cells 2002: Genetics And Function: Fourth Internatioal Symposium

by Orlic, Donald; Brummendorf, Tim H.; Fibbe, Willem; Sharkis, Saul; Kanz, Lothar

• ISBN13: 9781573314671
• ISBN10: 1573314676
• Format: Paperback
• Copyright: 2003-06-01
• Publisher: New York Academy of Sciences

Table of Contents

Preface.
By DONALD ORLIC, TIM H. BRUMMENDORF, WILLEM FIBBE, SAUL SHARKIS, AND LOTHAR KANZ	ix
Part I. Myeloid Disorders
New Models to Investigate Mechanisms of Disease Genesis from Primitive BCR-ABL+ Hematopoietic Cells.
By CONNIE EAVES, XIAOYAN JIANG, WOLFGANG EISTERER, YVES CHALANDON, G. PORADA, ESMAIL ZANJANI, AND ALLEN EAVES	1	(9)
Identification, Characterization, and Function of a Novel Oncogene: The Peripheral Cannabinoid Receptor Cb2.
By MERITXELL ALBERICH JORDA, NAZIK RAYMAN, PETER VALK, EVA DE WEE, AND RUUD DELWEL	10	(7)
Thrombopoietin Is Essential for the Maintenance of Normal Hematopoiesis in Humans: Development of Aplastic Anemia in Patients with Congenital Amegakaryocytic Thrombocytopenia.
By M. BALLMAIER, M. GERMESHAUSEN, S. KRUKEMEIER, AND K. WELTE	17	(9)
Normalization of Previously Shortened Telomere Length under Treatment with Imatinib Argues against a Preexisting Telomere Length Deficit in Normal Hematopoietic Stem Cells from Patients with Chronic Myeloid Leukemia.
By TIM H. BRÜMMENDORF, INCI ERSÖZ, ULRIKE HARTMANN, STEFAN BALABANOV, HOLGER WOLKE, PETER PASCHKA, TANJA LAHAYE, BIRGIT BERNER, KEROL BARTOLOVIC, SEBASTIAN KREIL, UTE BERGER, HARALD GSCHAIDMEIER, CARSTEN BOKEMEYER, RÜDIGER HEHLMANN, KLAUS DIETZ, PETER M. LANSDORP, LOTHAR KANZ, AND ANDREAS HOCHHAUS	26	(13)
Part II. Regulation of Stem Cells
Thrombopoietin: Accumulating Evidence for an Important Biological Effect on the Hematopoietic Stem Cell.
By KENNETH KAUSHANSKY	39	(5)
Telomeres in Hematopoietic Stem Cells.
By GABRIELA M. BAERLOCHER, ALEXANDER RÖTH, AND PETER M. LANSDORP	44	(5)
Angiogenic Factors Reconstitute Hematopoiesis by Recruiting Stem Cells from Bone Marrow Microenvironment.
By SHAHIN RAFII, SCOTT AVECILLA, SERGEY SHMELKOV, KOJI SHIDO, RAFAEL TEJADA, MALCOLM A.S. MOORE, BEATE HEISSIG, AND KOICHI HATTORI	49	(12)
Nonpeptide Mediators in the Hematopoietic Microenvironment.
By ROBERT MÖHLE, ANDREAS M. BOEHMLER, CLAUDIO DENZLINGER, AND LOTHAR KANZ	61	(6)
Characterization of Cord Blood Hematopoietic Stem Cells.
By FRÉDÉRIC MAZURIER, MONICA DOEDENS, OLGA I. GAN, AND JOHN E. DICK	67	(5)
Hematopoietic Stem Cell Transplantation across Major Genetic Barriers: Tolerance Induction by Megadose CD34 Cells and Other Veto Cells.
By YAIR REISNER, HILIT GUR, SHLOMIT REICH-ZELIGER, MASSIMO F. MARTELLI, AND ESTHER BACHAR-LUSTIG	72	(8)
Complement-Fixing CD45 Monoclonal Antibodies to Facilitate Stem Cell Transplantation in Mouse and Man.
By MALCOLM K. BRENNER, GERALD G. WULF, DONNA R. RILL, KANG-LI LUO, MARGARET A. GOODELL, ZUYONG MEI, INGRID KUEHNLE, MICHAEL P. BROWN, MARTIN PULÉ, HELEN E. HESLOP, AND ROBERT A. KRANCE	80	(9)
Part III. Gene Expression and Transfer
Differential Gene Expression Underlying the Functional Distinctions of Primary Human CD34+ Hematopoietic Stem and Progenitor Cells from Peripheral Blood and Bone Marrow.
By ULRICH STEIDL, RALF KRONENWETT, AND RAINER HAAS	89	(12)
Development of Gene Therapy for Hemoglobin Disorders.
By ARTHUR W. NIENHUIS, HIDEKI HANAWA, NOBUKUNI SAWAI, BRIAN P. SORRENTINO, AND DEREK A. PERSONS	101	(11)
Efficient Characterization of Retro-, Lenti-, and Foamyvector-Transduced Cell Populations by High-Accuracy Insertion Site Sequencing.
By MANFRED SCHMIDT, HANNO GLIMM, MANUELA WISSLER, GESA HOFFMANN, KARIN OLSSON, STEPHANIE SELLERS, DENISE CARBONARO, JOHN F. TISDALE, CORDULA LEURS, HELMUT HANENBERG, CYNTHIA E. DUNBAR, HANS-PETER KIEM, STEFAN KARLSSON, DONALD B. KOHN, DAVID WILLIAMS, AND CHRISTOF VON KALLE	112	(10)
Part IV. Stem Cells in Development
From Embryos to Embryoid Bodies: Generating Blood from Embryonic Stem Cells.
By GEORGE Q. DALEY	122	(10)
Hematopoietic Stem Cell Emergence in the Human Embryo and Fetus.
By BRUNO PÉAULT AND MANUELA TAVIAN	132	(9)
Part V. Adult Hematopoietic Stem Cells
Biology and Plasticity of CD133+ Hematopoietic Stem Cells.
By RUPERT HANDGRETINGER, PAUL R. GORDON, THASIA LEIMIG, XIAOHUA CHEN, HANS-JÖRG BÜHRING, DIETRICH NIETHAMMER, AND SELIM KUÇI	141	(11)
Adult Bone Marrow Stem Cells Regenerate Myocardium in Ischemic Heart Disease.
By DONALD ORLIC	152	(6)
Pluripotent Stem Cells Identified in Multiple Murine Tissues.
By JONATHAN C. HOWELL, WEI-HUA LEE, PAUL MORRISON, JIN ZHONG, MERVIN C. YODER, AND EDWARD F. SROUR	158	(16)
Transplanted Human Cord Blood Cells Give Rise to Hepatocytes in Engrafted Mice.
By FUMIHIKO ISHIKAWA, CHRISTOPHER J. DRAKE, SU YANG, PAUL A. FLEMING, HITOSHI MINAMIGUCHI, RICHARD P. VISCONTI, CHRISTOPHER V. CROSBY, W. SCOTT ARGRAVES, MINE HARADA, L. LYNDON KEY, JR., ANNE G. LIVINGSTON, JOHN R. WINGARD, AND MAKIO OGAWA	174	(12)
Part VI. Stem Cell Phenotype
Early Stages of Hematopoietic Differentiation.
By GERALD J. SPANGRUDE, S. SCOTT PERRY, AND WILLIAM B. SLAYTON	186	(9)
Major Age-Related Changes of Mouse Hematopoietic Stem/Progenitor Cells.
By MIJUNG KIM, HEE-BOM MOON, AND GERALD J. SPANGRUDE	195	(14)
Marrow Stem Cell Potential within a Continuum.
By P. QUESENBERRY, G. COLVIN, J.F. LAMBERT, M. ABEDI, J. CERNY, M. DOONER, B. MOORE, C. MCAULIFFE, D. DEMERS, D. GREER, A. PARENT, E. BADIAVAS, L. LUM, AND V. FALANGA	209	(13)
CDCP1 Is a Novel Marker for Hematopoietic Stem Cells.
By TIM CONZE, REINER LAMMERS, SELIM KUÇI, MARWA SCHERL-MOSTAGEER, NORBERT SCHWEIFER, LOTHAR KANZ, AND HANS-JÖRG BÜHRING	222	(5)
Antibody W7C5 Defines a CD109 Epitope Expressed on CD34+ and CD34-Hematopoietic and Mesenchymal Stem Cell Subsets.
By CHRISTINA GIESERT, ANKE MARXER, D. ROBERT SUTHERLAND, ANDRE C. SCHUH, LOTHAR KANZ, AND HANS-JÖRG BÜHRING	227	(4)
Part VII. Adult Mesenchymal Stem Cells
Unexpected Potential of Adult Stem Cells.
By C.M. VERFAILLIE, R. SCHWARTZ, M. REYES, AND Y. JIANG	231	(4)
Mesenchymal Stem Cells and Hematopoietic Stem Cell Transplantation.
By WILLEM E. FIBBE AND WILLY A. NOORT	235	(10)
The Mesenchymal Stroma Negatively Regulates B Cell Lymphopoiesis through the Expression of Activin A.
By TSIPI SHOHAM, RESHMI PARAMESWARAN, YARON SHAV-TAL, MIRA BARDA-SAAD, AND DOV ZIPORI	245	(16)
Index of Contributors	261