Foreword | |
Preface | |
Contributors | |
Strategies for the Use of Agents at High Dose | |
Pharmacologic Strategies for High-Dose Chemotherapy | p. 3 |
Preclinical Models for High-Dose Therapy | p. 14 |
Pharmacokinetics | p. 43 |
Strategies for the Use of Total Body Irradiation as Systemic Therapy in Leukemia and Lymphoma | p. 61 |
Radioimmunoglobulin Therapy | p. 84 |
What Is the Best Strategy for Bone Marrow Transplantation Cancer? | p. 124 |
Analysis of Economic Issues | p. 127 |
Reestablishing Hematopoiesis after Dose-Intensive Therapy | |
Transplantation | |
The Hematopoietic Microenvironment | p. 143 |
Reconstitution of Hematopoiesis Following Allogeneic Bone Marrow Transplantation | p. 151 |
Autologous Bone Marrow Transplantation | p. 162 |
Reestablishing Hematopoiesis After Dose-Intensive Therapy with Peripheral Stem Cells | p. 182 |
High-Dose Cancer Therapy Without Stem Cell Support - Human Solid Tumors | p. 195 |
Immunologic Reconstitution After High-Dose Chemoradiotherapy and Allogeneic or Autologous Bone Marrow or Peripheral Blood Hematopoietic Stem Cell Transplantation | p. 211 |
Marrow Contamination | |
Marrow Contamination: Detection and Significance | p. 226 |
Bone Marrow Purging | p. 249 |
Marrow Contamination: Positive Selection | p. 276 |
Growth Factors | |
Hematopoietic Growth Factors | p. 289 |
Granulocyte-Monocyte Colony-Stimulating Factor | p. 314 |
Delivery of High-Dose Chemotherapy with Recombinant Human Granulocyte Colony-Stimulating Factor Support | p. 333 |
Macrophage Colony-Stimulating Factor: Biology and Clinical Applications | p. 344 |
Interleukin 3: General Biology, Preclinical and Clinical Studies | p. 362 |
Erythropoietin in High-Dose Chemotherapy | p. 385 |
Laboratory and Clinical Support for Dose-Intensive Therapy | |
Nursing for Patients Receiving High-Dose Chemotherapy with Hematopoietic Rescue | p. 405 |
Hickman Line Management | p. 419 |
Blood Bank Support in Patients Undergoing High-Dose Cancer Therapy | p. 437 |
Infectious Diseases | p. 456 |
Pulmonary Complications of Bone Marrow Transplantation | p. 473 |
Hepatic Complications of Bone Marrow Transplantation | p. 487 |
The Cardiovascular System and Anticancer Therapy | p. 505 |
Dermatology | p. 518 |
Genitourinary, Gastrointestinal, and Other Complications | p. 547 |
Gonadal Complications | p. 555 |
Clinical Applications of High-Dose Therapy | |
High-Dose Therapy for Acute Myelocytic Leukemia | p. 569 |
High-Dose Therapy in Acute Lymphoblastic Leukemia | p. 607 |
Intensive Therapy of Chronic Myelogenous Leukemia | p. 619 |
High-Dose Therapy and Allogeneic Bone Marrow Transplantation in Chronic Lymphocytic Leukemia | p. 626 |
High-Dose Therapy, Autologous Stem Cells, and Hematopoietic Growth Factors for the Management of Multiple Myeloma | p. 638 |
Autologous Bone Marrow Transplantation for Hodgkin's Disease | p. 651 |
High-Dose Therapy for the Treatment of Non-Hodgkin's Lymphoma | p. 662 |
High-Dose Therapy in Burkitt's Lymphoma | p. 677 |
High-Dose Chemotherapy in the Management of Malignant Germ Cell Tumors | p. 690 |
Dose-Intensive Therapy in Breast Cancer | p. 701 |
High-Dose Chemotherapy with Autologous Bone Marrow Support for Lung Cancer | p. 719 |
High-Dose Chemotherapy and Autologous Marrow Transplantation for Common Epithelial Ovarian Cancer | p. 729 |
Myeloablative Treatment Supported by Marrow Infusions for Children with Neuroblastoma | p. 735 |
Dose-Intensive Therapy for Advanced Melanoma | p. 750 |
High-Dose Therapy for Brain Tumors: Rationale, Results, and Revelations | p. 755 |
Autologous Bone Marrow Transplantation for Miscellaneous Tumors | p. 763 |
Index | p. 773 |
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