Human Genetics and Genomics

by Korf, Bruce R.

• ISBN13: 9780632046560
• ISBN10: 0632046562
• Edition: 3rd
• Format: Paperback
• Copyright: 2006-12-25
• Publisher: Wiley-Blackwell

Summary

Human Genetics and Genomics, Third Edition, is the new rendition of the classic textbook Human Genetics: A Problem-Based Approach. Thoroughly updated and restructured, this brand new edition uses both a classic didactic approach to teach basic genetic concepts and a problem-based approach to demonstrate the clinical applications of genetics in medical practice. By combining both these approaches, Human Genetics and Genomics is suitable both as a textbook for genetics courses, and as a bridge into the clinical environment.The third edition features greater emphasis on cutting edge technologies and the latest genetic issues, and a vast array of new pedagogy, such as: Clinical snapshots covering major genetic disorders Ethical Implications boxes discussing related ethical issues Key summary points at the beginning of each chapter and Q&As at the end of each chapter for self-assessment Hot topics covering new and emerging areas in genetics Recommended reading for each chapter A companion website at www.blackwellpublishing.com/korfgenetics

Author Biography

Professor Bruce R. Korf, Department of Genetics, University of Alabama, Birmingham, Alabama, USA

Table of Contents

Preface	vii
Acknowledgments	ix
PART ONE: BASIC PRINCIPLES OF HUMAN GENETICS
DNA Structure and Function	2	(17)
Genetic Variation	19	(16)
Patterns of Inheritance	35	(27)
The Human Genome	62	(22)
Multifactorial Inheritance	84	(13)
Cell Division and Chromosomes	97	(29)
Population Genetics	126	(13)
Cancer Genetics	139	(21)
PART TWO: GENETICS IN MEDICAL PRACTICE
Chromosome Translocation	160	(11)
Molecular Diagnosis	171	(17)
Newborn Screening	188	(9)
Developmental Genetics	197	(10)
Carrier Screening	207	(11)
Genetic Risk Assessment	218	(7)
Genetic Testing for Risk of Cancer	225	(8)
Pharmacogenetics	233	(8)
Gene Therapy	241	(7)
Answers to Review Questions	248	(7)
Glossary	255	(12)
Index	267