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Abbreviations | |
Preface to the first edition | |
Preface to the second edition | |
Before we start - genetic data and the Internet | |
DNA structure and gene expression | p. 1 |
Chromosomes in cells | p. 27 |
Genes in pedigrees | p. 55 |
Cell-based DNA cloning | p. 71 |
Nucleic acid hybridization assays | p. 95 |
PCR, DNA sequencing and in vitro mutagenesis | p. 119 |
Organization of the human genome | p. 139 |
Human gene expression | p. 169 |
Instability of the human genome: mutation and DNA repair | p. 209 |
Physical and transcript mapping | p. 241 |
Genetic mapping of mendelian characters | p. 269 |
Genetic mapping of complex characters | p. 283 |
Genome projects | p. 295 |
Our place in the tree of life | p. 315 |
Identifying human disease genes | p. 351 |
Molecular pathology | p. 377 |
Genetic testing in individuals and populations | p. 401 |
Cancer genetics | p. 427 |
Complex diseases: theory and results | p. 445 |
Studying human gene structure, expression and function using cultured cells and cell extracts | p. 465 |
Genetic manipulation of animals | p. 491 |
Gene therapy and other molecular genetic-based therapeutic approaches | p. 515 |
Glossary | p. 545 |
Indexes | p. 557 |
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