Hypertension and Hormone Mechanisms

by Carey, Robert M.

• ISBN13: 9781588294081
• ISBN10: 1588294080
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-11-30
• Publisher: Humana Pr Inc

Summary

Hypertension and Hormone Mechanisms reviews novel developments in the endocrinology of hypertension with emphasis on new discovery during the past five years and perspectives on the future. Written by authors who have spearheaded recent advances, chapters cover innovations in our understanding of the reninangiotensin-aldosterone, the sympathoadrenal, and the renal dopaminergic systems. World-renowed researchers also discuss natriuretic peptides, vasoactive substances and vasopeptidases, insulin, free fatty acids, and the insulin resistance syndrome, sex hormones, and the vasculature and selected areas of diagnosis and therapy. With a focus on new developments in hormones and autacoids related to hypertension, Hypertension and Hormone Mechanisms provides a resource that will lead to new, active research in the fundamental mechanisms of hypertension.

Table of Contents

Preface	p. v
Contributors	p. ix
List of Color Plates	p. xiii
New Developments in the Renin-Angiotensin System
The Intrarenal Renin-Angiotensin System	p. 3
Cardiac and Vascular Renin-Angiotensin Systems	p. 23
Regulation of Cardiovascular Control Mechanisms by Angiotensin-(1-7) and Angiotensin-Converting Enzyme 2	p. 43
Angiotensin IV Binding Site: The AT[subscript 4] Receptor or Insulin-Regulated Aminopeptidase	p. 61
Angiotensin AT[subscript 2] Receptors in Blood Pressure Regulation	p. 75
Angiotensin II and Inflammation	p. 91
Aldosterone and Vascular Damage	p. 111
The Sympatho-Adrenal System in Hypertension
Neurogenic Human Hypertension	p. 129
Calcitonin Gene-Related Peptide and Hypertension	p. 143
The Renal Dopaminergic System, Hypertension, and Salt Sensitivity	p. 159
Metabolic Disorders and Hypertension
Insulin Resistance and Hypertension	p. 175
Fatty Acids, Cell Signaling, and Cardiovascular Risk	p. 187
Goal-Oriented Hypertension Management in Diabetic and Nondiabetic Patients	p. 205
Endothelial Hormones and Autocoids in Hypertension
Nitric Oxide and Hypertension	p. 225
Role of Endothelin-1 in Hypertension	p. 245
The Kallikrein-Kinin System and Hypertension	p. 259
Other Hormonal Systems and Hypertension
Physiology of Natriuretic Peptides and Their Receptors	p. 277
Sex Steroids and Hypertension	p. 307
The Lipoxygenase System in the Vasculature and Hypertension	p. 335
Index	p. 365
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