Hyperthermic and Hypermetabolic Disorders: Exertional Heat-stroke, Malignant Hyperthermia and Related Syndromes

by Edited by Philip M. Hopkins , F. R. Ellis

• ISBN13: 9780521443814
• ISBN10: 0521443814
• Format: Hardcover
• Copyright: 1996-10-28
• Publisher: Cambridge University Press

Summary

This authoritative and comprehensive new publication looks in depth at a range of medical syndromes characterized by serious and unpredicted internal overheating of the body. As a result of heat stress, exceptional physical exertion, or in response to certain drugs, these episodes may arise suddenly and unexpectedly, with life-threatening consequences. This text's contributions focus on the full range of these syndromes, their metabolic and physiological bases, the important predisposing factors that determine those at risk, and the medical management of these conditions. The volume incorporates a wealth of information from the Leeds Malignant Hyperthermia Investigation Unit--the world's leading center of research and investigation in this area.

Table of Contents

Part I. Exertional Heatstroke: 1. History and epidemiology: definitions and groups at risk J. G. Dickinson

2. Predisposing factors, clinical features, treatment and prevention J. G. Dickinson

3. Pathophysiology of heatstroke J. P. Knochel

4. Investigation of heat stroke victims 1: the human physiology laboratory C. G. Batty and W. A. Freeland

5. Investigation of heat stroke victims 2: nuclear magnetic resonance spectroscopy J.-F. Payen and P. Stieglitz

6. Investigation of exertional heat stroke 3: in vitro skeletal muscle contracture testing P. M. Hopkins, P. J. Halsall and F. R. Ellis

7. Future research in exertional heat stroke P. M. Hopkins

Part II. Malignant Hyperthermia: 8. The clinical presentation of malignant hyperthermia P. J. Halsall

9. Malignant hyperthermia: clinical management G. A. Gronert and J. F. Antognini

10. Pathophysiology of malignant hyperthermia J. E. Fletcher and H. Rosenberg

11. Screening for malignant hyperthermia susceptibility P. J. Halsall

12. Skeletal muscle morphology P. Harnden

13. The genetics of malignant hyperthermia Sarah P. West

14. Porcine stress syndrome J. Dinsmore and G. M. Hall

Part III. Other Hypermetabolic Syndromes: 15. Neuroleptic malignant syndrome P. J. Adnet, H. Reyford and R. M. Krivosic-Horger

16. Hyperthermic and hypermetabolic disorders J. A. Henry

17. Hypermetabolism in endocrine disorders P. Belchetz

Index.