Illuminating Life: Selected Papers from Cold Spring Harbor, Volume 1 (1903-1969)

by Witkowski, Jan A.

• ISBN13: 9780879695668
• ISBN10: 0879695668
• Edition: 1st
• Format: Hardcover
• Copyright: 1999-11-01
• Publisher: Cold Spring Harbor Laboratory Press

Summary

This volume showcases reprints of 20 significant papers published by scientists while at Cold Spring Harbor Laboratory, with a non-technical explanation of the work's significance at the time and a profile of the investigator concerned.

Author Biography

Jan Witkowski, Ph.D. trained in biochemistry at the University of London. Since 1987, he has been the Director of the Banbury Center, Cold Spring Harbor, New York.

Table of Contents

Foreword	vii
Preface	ix
Acknowledgments	xiii
Prologue: How the Laboratory Was Planted at Cold Spring Harbor and Why It Grew There	xv
Ecology, Adaptation, and Evolution---Early Research at Cold Spring Harbor	1	(22)
The Animal Ecology of the Cold Spring Sand Spit, with Remarks on the Theory of Adaptation
Davenport C.B.
The Early Applications of Mendel's Genetics to Human Beings	23	(6)
Heredity of Eye-Color in Man
Davenport G.C.
Davenport C.B.
The Development of Hybrid Corn at Cold Spring Harbor	29	(18)
The Composition of a Field of Maize
Shull G.H.
A Pure-line Method in Corn Breeding
Shull G.H.
Chromosomal Changes and Heredity	47	(6)
Chromosomal Duplication and Mendelian Phenomena in Datura Mutants
Blakeslee A.F.
Belling J.
Farnham M.E.
Mouse Headquarters, Cold Spring Harbor	53	(24)
The Heredity of Susceptibility to a Transplantable Sarcoma (J.W.B.) of the Japanese Waltzing Mouse
Little C.C.
Studies on Leukemia in Mice: I: The Experimental Transmission of Leukemia
Richter M.N.
MacDowell E.C.
Unstable Genes in Drosophila	77	(10)
Reddish---A Frequently ``Mutating'' Character in Drosophila virilis
Demerec M.
Quantitative Biology Comes to the Biological Laboratory---Isolating Hormones	87	(8)
The Treatment of Patients with Addison's Disease with the ``Cortical Hormone'' of Swingle and Pfiffner
Rowntree L.G.
Greene C.H.
Swingle W.W.
Pfiffner J.J.
The Genetics of Taste and Smell	95	(14)
Genetics of Sensory Thresholds: Taste for Phenylthiocarbamide
Blakeslee A.F.
Pigeons, Hormones, and Lactation	109	(8)
A New Hormone of the Anterior Pituitary
Riddle O.
Bates R.W.
Dykshorn S.W.
Quantitative Biology: Biophysics in the Biological Laboratory	117	(8)
Electric Impedance of Suspensions of Yeast Cells
Fricke H.
Curtis H.J.
Broken Chromosomes	125	(10)
The Fusion of Broken Ends of Chromosomes following Nuclear Fusion
McClintock B.
Penicillin: The Department of Genetics at War	135	(10)
Production of Penicillin. United States Patent
Demerec M.
Development of a High-yielding Strain of Penicillium
Demerec M.
The Unstable Genome---Movable Genes	145	(40)
Chromosome Organization and Genic Expression
McClintock B.
Dissecting the Bacteriophage Life Cycle	185	(16)
The Intracellular Growth of Bacteriophages. I. Liberation of Intracellular T4 by Premature Lysis with Another Phage or with Cyanide
Doermann A.
The Hershey--Chase Experiment	201	(22)
Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage
Hershey A.
Chase M.
Assembly Line Genes	223	(34)
Tryptophan Mutants in Salmonella typhimurium
Demerec M.
Hartman Z.
First Glimpses of DNA Repair	257	(22)
Time, Temperature, and Protein Synthesis: A Study of Ultraviolet-induced Mutation in Bacteria
Witkin E.M.
DNA and the T2 Phage Chromosome	279	(12)
An Estimate of the Length of the DNA Molecule of T2 Bacteriophage by Autoradiography
Cairns J.
The Sticky Ends of Phage λ and Their Uses	291	(12)
Cohesion of DNA Molecules Isolated from Phage Lambda
Hershey A.D.
Burgi E.
Ingraham L.
DNA Synthesis and the Case of the Missing Enzyme	303	(70)
Isolation of an E. coli Strain with a Mutation Affecting DNA Polymerase
De Lucia P.
Cairns J.
Appendices: Directors at Cold Spring Harbor
Charles B. Davenport	311	(50)
Charles Benedict Davenport 1866--1944. A Study of Conflicting Influences
MacDowell E.C.
Reginald G. Harris	361	(6)
Anonymous. 1982. Reginald Harris and the Biological Laboratory
Milislav Demerec	367	(6)
Milislav Demerec 1895--1966
Wallace B.
Name Index	373	(6)
Subject Index	379