did-you-know? rent-now

Amazon no longer offers textbook rentals. We do!

did-you-know? rent-now

Amazon no longer offers textbook rentals. We do!

We're the #1 textbook rental company. Let us show you why.

9780120536405

Immunoglobulin Genes

by ;
  • ISBN13:

    9780120536405

  • ISBN10:

    0120536404

  • Edition: 2nd
  • Format: Hardcover
  • Copyright: 1995-09-01
  • Publisher: Academic Press

Note: Supplemental materials are not guaranteed with Rental or Used book purchases.

Purchase Benefits

  • Free Shipping Icon Free Shipping On Orders Over $35!
    Your order must be $35 or more to qualify for free economy shipping. Bulk sales, PO's, Marketplace items, eBooks and apparel do not qualify for this offer.
  • eCampus.com Logo Get Rewarded for Ordering Your Textbooks! Enroll Now
  • Write a Review Icon Write a Review
  • Complimentary 7-Day eTextbook Access - Read more
    When you rent or buy this book, you will receive complimentary 7-day online access to the eTextbook version from your PC, Mac, tablet, or smartphone. Feature not included on Marketplace Items.
List Price: $78.00 Save up to $28.86
  • Rent Book $49.14
    Add to Cart Free Shipping Icon Free Shipping

    TERM
    PRICE
    DUE

    7-Day eTextbook Access 7-Day eTextbook Access

    USUALLY SHIPS IN 3-5 BUSINESS DAYS
    *This item is part of an exclusive publisher rental program and requires an additional convenience fee. This fee will be reflected in the shopping cart.

Supplemental Materials

What is included with this book?

Summary

The immunoglobulin gene complex is responsible for generating an extraordinarily wide range of antibodies, each possessing a unique antigen specificity. The Second Edition of Immunoglobulin Genes brings the reader up to date with the rapid progress in our understanding of this system. Firmly established as the definitive book on the topic, it provides a fully comprehensive account of the organization, function, rearrangement and expression of these and related genes. Since the publication of the first edition, the work has been extensively revised and updated to cover new research data on human immunoglobulin genes as well as mammalian and lower vertebrate systems. New chapters include "Somatic mutation and B cell Maturation", "Antigen receptors" and "B lymphocyte tolerance in the mouse." For the immunologist, there are detailed descriptions of the molecular mechanisms which generate this diverse range of antibodies and the tight regulation of the genes encoding them. Molecular biologists will find discussions of important phenomena including gene rearrangement, differential splicing and deletion in the context of immunoglobulin genes. The excitement of research on immunoglobulin genes is conveyed by the range and complexity of issues discussed here; the book contains invaluable information for clinicians and research scientists with an interest in the immune response. * Conveys the excitement of research on immunoglobulin genes by the range and complexity of issues * Contains invaluable information for clinicians and research scientists with an interest in the immune response * For the Immunologist * Detailed descriptions of the molecular mechanisms generating this diverse range of antibodies and the regulation of genes encoding them * For the Molecular Biologist * Discusses important phenomena including gene rearrangement, differential splicing, and deletion in the context of immunoglobulin genes.

Table of Contents

B Cells: Human B-Cell Differentiation
Murine B-Cell Differentiation
Somatic Mutation and B-Cell Maturation
Development of B-Cell Subsets
Regulation of B-Cell Differentiation By Stroma Cells
Antigen Receptors
Organization and Rearrangement of Immunoglobulin Genes: Immunoglobulin Heavy Chain Loci in Mouse and Men
The Human Immunoglobulin Genes
Organization of Lambda Chain Genes
VDJ Recombination
Regulation of Class Switch Recombination of the Immunoglobulin Heavy Chain Genes
Organization and Expression of Chicken and Sheep Ig Genes
Immunoglobulin Heavy Chain Genes of Rabbit
The Structure and Organization of Immunoglobulin Genes in Lower Vertebrates
Immunoglobulin Gene Expression: Ig Gene Expression and Regulation in Ig Transgenic Mice
B-Lymphocyte Tolerance in the Mouse
Auto Antibodies
Regulation of Ig H and L Chain Gene Transcription
Subject Index
Table of Contents provided by Publisher. All Rights Reserved.

Supplemental Materials

What is included with this book?

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.

Rewards Program