Immunology

by Male, David

• ISBN13: 9780323033992
• ISBN10: 0323033997
• Edition: 7th
• Format: Paperback
• Copyright: 2006-04-01
• Publisher: HARCOURT HEALTH SCIENCES-MOSBY

Summary

Extensively updated, with new contributors, brilliant new illustrations and a wealth of supporting material online, this 7th edition offers you a carefully structured approach to learning the building blocks of the immune system as well as initiation and actions of the immune response. The website which accompanies this text gives access to all the images in the book, up to 20 detailed animation sequences (which link to further supporting text, illustrations, molecular models and video clips), 8 lectures which explain how the immune system responds to different infections or to tissue grafts, and a test bank of 300 USMLE-style questions. Includes Critical Thinking Boxes which encourage you to think immunologically and help you test your own understanding of material. Provides extensive additional material online. Incorporates clinical cases at the end of chapters to give you a realistic clinical context in which to anchor your understanding of immunology. Uses high-yield-style chapter summaries to allow you a quick and effective way to double check all key concepts. Strengthened chapter opening objectives give a clearer idea of what you should know by the end of each chapter. Includes STUDENT CONSULT access.

Table of Contents

Preface and user guide	vii
List of Contributors	ix
Section 1 Components of the Immune System
Introduction to the immune system	3	(16)
David Male
Cells, tissues and organs of the immune system	19	(40)
Peter Lydyard
Carlo E Grossi
Antibodies	59	(28)
Roy jefferis
Complement	87	(18)
B Paul Morgan
T cell receptors and MHC molecules	105	(22)
David B Roth
Section 2 Modes of Immune Response
Mechanisms of innate immunity	127	(18)
David Male
Antigen presentation	145	(18)
John Trowsdale
Cell Cooperation in the antibody response	163	(18)
Joseph C Marini
Mononuclear phagocytes in immune defence	181	(22)
Siamon Gordon
Cell mediated cytotoxicity	203	(12)
Gillian M Griffiths
Regulation of the immune response	215	(20)
Arne Akbar
Joanne E Cook
Immune responses in tissues	235	(12)
David Male
Section 3 Defence Against Infectious Agents
Immunity to viruses	247	(10)
Anthony A Nash
Immunity to bacteria and fungi	257	(20)
Gregory J Bancroft
Immunity to protozoa and worms	277	(22)
Janette E Bradley
Richard Pleass
Primary immunodeficiency	299	(12)
Fred S Rosen
AIDS and secondary immunodeficiency	311	(14)
Bruce D Walker
Vaccination	325	(18)
Peter C L Beverley
Section 4 Immune Responses Against Tissues
Immunological tolerance	343	(22)
D C Wraith
Autoimmunity and autoimmune disease	365	(18)
Ivan Roitt
Transplantation and rejection	383	(18)
Robert Lechler
Andrew J T George
Immunity to Cancers	401	(22)
P K Srivastava
Section 5 Hypersensitivity
Immediate hypersensitivity (Type I)	423	(26)
Thomas A E Platts-Mills
Hypersensitivity (Type II)	449	(12)
David Male
Hypersensitivity (Type III)	461	(16)
Frank Hay
Olwyn M R Westwood
Type IV hypersensitivity	477	(16)
Warwick Britton
Explanations for critical thinking and case studies	493	(34)
Appendices
Major histocompatibility complex	507	(1)
Recognized CD markers of hemopoietic cells and their distribution	508	(14)
The major cytokines	522	(2)
Human chemokines and their receptors	524	(3)
Glossary	527	(8)
Index	535