Immunology at a Glance, 8th Edition

by JHL Playfair (University College, London); Benjamin Chain (University College London)

• ISBN13: 9781405131339
• ISBN10: 1405131330
• Edition: 8th
• Format: Paperback
• Copyright: 2005-10-01
• Publisher: Wiley-Blackwell

Summary

Immunology at a Glance provides a concise, and accessible introduction and revision aid for undergraduate medical and science students. Following the familiar, easy-to-use at a Glance format, each topic is presented as a double-page spread with key facts accompanied by clear, informative line diagrams illustrating the essential points.This new edition of Immunology at a Glance:Contains a second colour throughout to enhance the visual appeal, making the subject even easier to understand Presents schematic diagrams on the left page and concise explanations of the right, showing the mechanisms involved in immunological processes Has been thoroughly revised and updated with brand new information on: recognition and receptors immunity and clinical medicine.Immunology at a Glance will continue to appeal to all students of biomedical science and medicine who want a quick, yet thorough grasp of immunology.Reviews of the last edition"It is pitched at the right level for 2nd MB students and will also act as a useful reminder to those students embarking on Part IV Pathology." St. Mary's Hospital Gazette"Professor Playfair has succeeded in offering a condensed, readable notebook or dictionary of immunology whose greatest worth rests with the simple yet intricate figures which highlight the 34 chapters." Trends in Biotechnology on the fourth edition

Author Biography

Professor John H L Playfair MB BChir PhD DSc, Emeritus Professor of Immunology, University College London, UK.

Professor Benjamin M Chain BA, PhD, FRCPath, Professor of Immunology and Head of Department at the Windeyer Institute of Medical Sciences, University College London, UK.

Table of Contents

Preface	p. 6
Acknowledgments	p. 6
Note on the eighth edition	p. 6
How to use this book	p. 7
Further reading	p. 7
Immunity
The scope of immunology	p. 8
Innate and adaptive immune mechanisms	p. 10
Recognition and receptors: the keys to immunity	p. 12
Evolution of immune mechanisms	p. 14
Cells involved in immunity: the haemopoietic system	p. 16
Innate immunity
Complement	p. 18
Acute inflammation	p. 20
Phagocytic cells: the reticuloendothelial system	p. 22
Phagocytosis	p. 24
Adaptive immunity
The cellular basis
Lymphocytes	p. 26
Primary lymphoid organs and lymphopoiesis	p. 28
Secondary lymphoid organs and lymphocyte traffic	p. 30
The molecular basis
Evolution of recognition molecules: the immunoglobulin superfamily	p. 32
The major histocompatibility complex	p. 34
The T-cell receptor	p. 36
Antibody diversification and synthesis	p. 38
Antibody structure and function	p. 40
The adaptive immune response
Antigen recognition and processing	p. 42
The antibody response	p. 44
Antigen-antibody interaction and immune complexes	p. 46
Cell-mediated immune responses	p. 48
Regulation
Tolerance	p. 50
Idiotypes, anti-idiotypes and networks	p. 52
The cytokine network	p. 54
Immunity, hormones and the brain	p. 56
Potentially useful immunity
Antimicrobial immunity: a general scheme	p. 58
Immunity to viruses	p. 60
Immunity to bacteria	p. 62
Immunity to fungi	p. 64
Immunity to protozoa	p. 66
Immunity to worms	p. 68
Immunity to tumours	p. 70
Undesirable effects of immunity
Harmful immunity: a general scheme	p. 72
Allergy and anaphylaxis	p. 74
Immune complexes, complement and disease	p. 76
Chronic and cell-mediated inflammation	p. 78
Autoimmunity	p. 80
Transplant rejection	p. 82
Altered immunity
Immunosuppression	p. 84
Immunodeficiency	p. 86
HIV and AIDS	p. 88
Immunostimulation and vaccination	p. 90
Summary
Immunity and clinical medicine	p. 92
Appendices
Comparative sizes	p. 94
Comparative molecular weights	p. 94
Landmarks in the history of immunology	p. 95
Some unsolved problems	p. 95
CD classification	p. 96
Index	p. 99
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