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9781405180528

Immunology at a Glance

by ;
  • ISBN13:

    9781405180528

  • ISBN10:

    1405180528

  • Edition: 9th
  • Format: Paperback
  • Copyright: 2009-03-17
  • Publisher: Wiley-Blackwell
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List Price: $41.95

Summary

This text presents a broad look at immunology with the aid of a series of sketches which show the mechanisms involved in the immunology process. This ninth edition has been completely updated, with new chapters on recognition and receptors and immunity in health and disease.

Author Biography

Professor John H L Playfair MB BChir PhD DSc, Emeritus Professor of Immunology, University College London, UK.

Professor Benjamin M Chain BA, PhD, FRCPath, Professor of Immunology and Head of Department at the Windeyer Institute of Medical Sciences, University College London, UK.

Table of Contents

Preface
Acknowledgements
Note on the ninth edition
How to use this book
Further reading
Immunity
The scope of immunology
Innate and adaptive immune mechanisms
Recognition and receptors: the keys to immunity
Evolution of immune mechanisms
Cells involved in immunity: the haemopoietic system
Innate immunity
Receptors of the innate immune system
Complement
Acute inflammation
Phagocytic cells and the reticuloendothelial system
Phagocytosis
Adaptive immunity. (i) The molecular basis
Evolution of recognition mechanisms: the immunoglobulin superfamily
The major histocompatibility complex
The T-cell receptor
Antibody diversification and synthesis
Antibody structure and function..(ii) The cellular basis
Lymphocytes
Primary lymphoid organs and lymphopoiesis
Secondary lymphoid organs and lymphocyte traffic.(iii) The adaptive immune response
Antigen processing and presentation
The antibody response
Antigen-antibody interaction and immune complexes
Cell-mediated immune responses.(iv) Regulation
Tolerance
Idiotypes, anti-idiotypes and networks
The cytokine network
Immunity, hormones and the brain
Potentially useful immunity
Anti-microbial immunity: a general scheme
Immunity to viruses
Immunity to bacteria
Immunity to fungi and ectoparasites
Immunity to protozoa
Immunity to worms
Immunity to tumours
Undesirable effects of immunity
Harmful immunity: a general scheme
Allergy and anaphylaxis
Immune complexes, complement and disease
Chronic and cell-mediated inflammation
Autoimmunity
Transplant rejection
Altered immunity
Immunosuppression
Immunodeficiency
HIV and AIDS
Immunostimulation and vaccination
Immunity in health and disease
Immunity and clinical medicine
Investigating immunity
Into the future: immunology in the age of genomics
Self-assessment
Self-assessment questions
Answers
Appendices
Comparative sizes and molecular weights
Landmarks in the history of immunology: some unsolved problems
CD classification
Table of Contents provided by Publisher. All Rights Reserved.

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