Immunology of the Lacrimal Gland, Tear Film and Ocular Surface

by Zierhut; Manfred

• ISBN13: 9781841845685
• ISBN10: 184184568X
• Edition: 1st
• Format: Hardcover
• Copyright: 2005-06-03
• Publisher: CRC Press

Summary

Evaluating our understanding of the lacrimal functional unit, this well-written and highly referenced text focuses on the immunological interrelationships between the lacrimal gland, conjunctiva, cornea and tear film in both health and disease.Written by Professor Zierhut, one of the world's leading specialists on uveitis, this important text focuses upon a variety of immune topics including:* mucosal immunity* lymphocyte homing* dendritic cell regulation* corneal immune privilege* ocular surface inflammation* autoimmune mechanisms.Immunology of the Lacrimal Gland, Tear Film and Ocular Surface will undoubtedly help to stimulate research on the lacrimal functional unit and lead the reader to new treatment strategies against inflammatory disorders of the ocular surface.

Table of Contents

MANFRED ZIERHUT, MICHAEL E. STERN AND DAVID A. SULLIVAN
Foreword	vii
PER BRANDTZAEG, FINN-EIRIK JOHANSEN, ESPEN S. BAEKKEVOLD AND INGER NINA FARSTAD
Lacrimal glands: role in mucosal immunity compared with other secretory effector sites	1	(12)
ERICH KNOP AND NADJA KNOP
Lymphocyte homing in the mucosal immune system to the eye-associated lymphoid tissue (EALT)	13	(30)
AUSTIN K. MIRCHEFF, SARAH F. HAMM-ALVAREZ, HARVEY R. KASLOW, JOEL E. SCHECHTER AND MELVIN D. TROUSDALE
Epithelial cells in lymphocyte regulation in the lacrimal gland	43	(28)
ROBERT A. SACK
Immune and inflammatory processes in the pre-ocular tear film in the closed eye and open eye environments	71	(8)
MONICA BERRY AND ROGER ELLINGHAM
Mucins on the ocular surface	79	(18)
FRIEDRICH PAULSEN, DEIKE VAROGA, PHILIPP STEVEN AND THOMAS PUFE
Antimicrobial peptides at the ocular surface	97	(8)
ROLAND JONSSON, PETER SZODORAY, KETIL MOEN AND MARIA K. JONSSON
Comparison of the lacrimal and salivary glands	105	(12)
JERRY Y. NIEDERKORN
Role of mucosal immunity in Acanthamoeba keratitis	117	(10)
J. WAYNE STREILEIN, CAROLINA V. ARANCIBIA-CARCAMO AND HIDEYA OSAWA
Antigen presentation and corneal transplantation	127	(14)
M. REZA DANA AND PEDRAM HAMRAH
Corneal antigen-presenting cells (APC): function and identity	141	(10)
ROGER BEUERMAN, MICHAEL E. STERN, DOAN NGUYEN, HIROSHI TOSHIDA AND JIANPING GAO
Homeostasis of the ocular surface: parasympathetic control of acinar cell gene expression	151	(10)
DAVID A. SULLIVAN, DEBRA A. SCHAUMBERG, FRANK SCHIRRA, TOMO SUZUKI, STEPHEN M. RICIIARDS, MENG LIU, ROSE M. SULLIVAN, M. REZA DANA AND BENJAMIN D. SULLIVAN
Sex, sex steroids and dry eye syndromes	161	(22)
ELISABETH M. MESSMER
Dry eye syndromes	183	(8)
MAURIZIO ROLANDO AND MARINA PAPADIA
Sjögren syndrome	191	(26)
STEFANO BONINI, ALESSANDRO LAMBIASIE, MAGDALENA CORTES, DIEGO OLZI AND SERGIO BONINI
Disorders of the ocular surface of allergic origin	217	(6)
MANFRED ZIERHUT, CHRISTOPH DEUTER, NICOLE STÜBIGER, KIRSTEN SIEPMANN AND MICHAEL E. STERN
Topical Cyclosporin A	223	(16)
MELISSA GLASSON, FIONA STAPLETON, LISA KEAY, MALCOLM BALL AND MARK WILLCOX
Effect of contact lens wear on the pre-corneal tear film	239	(16)
JUDITH A. WHITTUM-HUDSON
Ocular chlamydial infections	255	(14)
BARRY T. ROUSE, SUJIN LEE, MEI ZHENG AND KAUSTUV BANERJEE
Herpetic stromal keratitis - aspects of its pathogenesis	269	(8)
Index	277