Immunology and Serology in Laboratory Medicine

by Turgeon

• ISBN13: 9780323023719
• ISBN10: 0323023711
• Edition: 3rd
• Format: Hardcover
• Copyright: 2003-02-28
• Publisher: Mosby

Summary

This book provides detailed and specific information on the theoretical concepts in immunology that are applicable to the laboratory sciences, underlying theories of procedures that are applicable to specific disorders, and selected disorders that are relevant to clinical laboratory science. The 3rd edition is a comprehensive, readable, student-friendly text featuring revised content and new, up-to-date information. The first two sections of the book provide foundation knowledge and skills that progress from basic immunologic mechanisms and serologic concepts, to the theory of laboratory procedures such as automated techniques. The final two sections emphasize medical applications that are relevant to clinical laboratory science, addressing representative disorders of infectious and immunologic origin as well as topics such as transplantation and tumor immunology. Each chapter begins with an outline and learning objectives, ending with a summary, review questions, and a bibliography. Most chapters also contain case studies and procedures that challenge readers to apply their knowledge to real-life situations. Instructor resources are available to qualified adopters; contact your sales representative for more information. Step-by-step procedures throughout the book combine both the immunological theories presented in the text with real-life laboratory tests. Comprehensive coverage presents the range of issues students need to learn in immunology and serology, also serving as an effective bench reference for practitioners. Various features such as the Chapter Outline, Learning Objectives, Procedures, Case Studies, Chapter Highlights, Review Questions, and Bibliography reinforce the most important points in each chapter and make information more memorable, eliminating the need for a separate study guide or lab manual. A vibrant two-color design enhances the text, illustrations, tables, and boxes to highlight important features. A glossary in the back of the book gives students convenient reference to succinct, accurate definitions of important words. New chapters Molecular Techniques (Chapter 11), Bone Marrow Transplantation (Chapter 29), and Tumor Immunology (Chapter 30) provide cutting-edge information to make the book more complete. New content covers the latest safety information, the newest diagnostic methods and therapeutics for AIDS, up-to-date information on understanding vaccines, inclusion of Apoptosis in the cell cycle, updated lymphocyte membrane characteristics, and a revised list of cytokines with immunologic functions. The chapter on Tick-Borne Diseases (Chapter 16) has been expanded to include Borreliosis and Ehrlichiosis in addition to new information on Lyme Disease. The chapter on The Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells (Chapter 4) has been revised to include T-Lymphocyte Membrane Markers. 20 new real-life clinical case studies have been added throughout the text. This edition provides over 425 new review questions, plus a new Test Your Immunology Vocabulary appendix that also contains 84 test questions. All of the line drawings have been redrawn in two-color to give the art a fresh, modern appearance.

Table of Contents

Part One Basic Immunologic Mechanisms	1	(115)
An Overview of Immunology	3	(12)
Antigens and Antibodies	15	(22)
The Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells	37	(18)
The Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells	55	(32)
Soluble Mediators of the Immune System	87	(28)
Part Two The Theory of Immunologic and Serologic Procedures	115	(70)
Safety and Basic Techniques in the Immunology-Serology Laboratory	117	(14)
Agglutination Methods	131	(10)
Electrophoresis Techniques	141	(8)
Labeling Techniques in Immunoassay	149	(8)
Automated Procedures	157	(8)
Molecular Techniques	165	(10)
Miscellaneous Techniques	175	(10)
Part Three Immunologic Manifestations of Infectious Diseases	185	(160)
The Immune Response in Infectious Diseases	187	(8)
Streptococcal Infections	195	(12)
Syphilis	207	(20)
Tick-Borne Diseases	227	(20)
Toxoplasmosis	247	(8)
Cytomegalovirus	255	(16)
Infectious Mononucleosis	271	(12)
Viral Hepatitis	283	(28)
Rubella Infection	311	(14)
Acquired Immunodeficiency Syndrome (AIDS)	325	(20)
Part Four Immunologically and Serologically Related Disorders	345	(146)
Hypersensitivity Reactions	347	(12)
Immunoproliferative Disorders	359	(14)
Autoimmune Disorders	373	(28)
Systemic Lupus Erythematosus	401	(20)
Rheumatoid Arthritis	421	(16)
Solid Organ Transplantation	437	(22)
Bone Marrow Transplantation	459	(14)
Tumor Immunology	473	(18)
Answers to Review Questions	491	(30)
Appendixes
A Preparing Dilutions and Serial Dilutions	495	(2)
B Review Questions	497	(4)
C Chronic Fatigue Syndrome	501	(6)
D A Primer on Vaccines	507	(4)
E Apoptosis	511	(2)
F Diagnostic Tests in Medical Laboratory Immunology	513	(8)
Glossary	521