Immunophenotypic Analysis, Second Edition

by Pßl=czi,Katalin

• ISBN13: 9781587061011
• ISBN10: 1587061015
• Edition: 2nd
• Format: Hardcover
• Copyright: 2004-12-21
• Publisher: CRC Press

Summary

National Institute of Haemotology and Immunology, Budapest, Hungary. Text provides information on the science and practice of immunophenotyping and flow cytometry. Data has been rewritten to reflect the expansion of knowledge. Previous edition, c1994, was titled Clinical Applications of Immunophenotypic Analysis. DNLM: Immunophenotyping.

Table of Contents

Immunologic Marker Analysis of Cells in the Various Stages of Hematopoietic Differentiation	p. 1
Differentiation Pathway of Normal Hematopoietic Cells	p. 1
International Nomenclature and Functional Characterization of Immunologic Markers	p. 2
Antigen-Specific Receptors of Lymphocytes	p. 8
Application of Monoclonal Antibodies to the Diagnosis and Classification of Acute Leukemias	p. 15
Need for Routine Immunophenotyping of Acute Leukemias	p. 15
Basic Distinction of AML versus ALL	p. 17
Immunological Classification of ALL	p. 18
Immunophenotypic Classification of Acute Myeloblastic Leukemia	p. 21
Biphenotypic Acute Leukemias	p. 23
The Definition of Remission and Minimal Residual Disease in Acute Leukemia by Immunophenotyping	p. 26
Immunophenotypic Markers in the Diagnosis and Classification of Non-Hodgkin's Lymphomas	p. 33
Distribution of Mature T and B Lymphocytes in the Lymph Nodes	p. 33
Lymphomas of the B cells	p. 34
Intermediate Grade B Cell Lymphomas	p. 44
Lymphomas of the T Cell Lineage	p. 47
Lymphocyte Activation and its Role in Lymphoma Genesis	p. 51
Phenotypic Characterization of Non-Hodgkin's Lymphomas as Tumors of Activated Lymphoid Cells	p. 55
Clinical Application of Immunophenotyping in Primary Immunodeficiencies	p. 65
Cellular and Combined Immunodeficiency Diseases	p. 66
Predominantly Antibody Deficiency Diseases	p. 70
The Role of Cell Surface Antigens in Bone Marrow and Stem Cell Transplantation	p. 77
Hematopoietic Stem Cells	p. 77
Human Embryonic Stem Cell Transplantation	p. 83
Umbilical Cord Blood Progenitors as a Source of Transplantable Hematopoietic Cells	p. 86
Peripheral Blood Stem Cell Transplantation	p. 86
Phenotypes of Recovering Lymphoid Cells After Bone Marrow Transplantation	p. 87
Immunological Mechanisms of Graft Failure	p. 89
Graft Versus Host Disease and Graft Versus Leukemia Effect	p. 90
Index	p. 105
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