Infections Associated With Indwelling Medical Devices

by Bisno, Alan L.; Waldvogel, Francis A.

• ISBN13: 9781555810771
• ISBN10: 1555810772
• Format: Hardcover
• Copyright: 1994-10-01
• Publisher: Amer Society for Microbiology

Summary

Indwelling prosthetic devices - such as catheters, heart valves, vascular bypass grafts, implanted ocular lenses, central nervous system shunts, artificial hips and intrauterine devices - have become a common and indispensable part of modern medical care. Infection is the main complication associated with these devices. This volume reviews available information about such infections. There is extensive consideration of the basic science aspects of foreign body infections, including the complex interactions between host, prosthesis and microorganism. The epidemiologic, microbiologic and clinical aspects of the major forms of prosthetic infections are considered in detail. Current concepts of management, including the role of prophylactic antibiotics are considered in detail.

Table of Contents

Foreign body infections: xperimental model, host factors, microbial factors;olecular study of S

aureus surface proteins interacting with plasma and matrix proteins

icrobial pathogenic factors

mall colony variants;icrobial pathogenic factors

iofilm mode of growth and slime production

iochemical and immunomodulating properties of extracellular slime substance

cular infections

nfections of central nervous system shunts

nfected orthopedic prostheses

nfections of prosthetic heart valves

nfections of vascular grafts

athogenesis, prevention and management of infections due to intravascular devices used for infusion therapy

nfections associated with endotracheal intubation and tracheostomy

nfections associated with foreign bodies in the urinary tract

nfections associated with peritoneal and hemodialysis

nfections of the female genital tract

ntimicrobial prophylaxis of infections associated with foreign bodies

ndex

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