Preface | p. ix |
Author Biographies | p. xiii |
Acknowledgments | p. xvii |
Syndromic Surveillance Systems | |
Infectious Disease Informatics: An Introduction and An Analysis Framework | p. 3 |
Public Health Syndromic Surveillance Systems | p. 9 |
Summary of Nationwide Syndromic Surveillance Systems | p. 10 |
Summary of Syndromic Surveillance Systems at the Local, County, and State Levels | p. 17 |
Summary of Industrial Solutions for Syndromic Surveillance | p. 25 |
Summary of International Syndromic Surveillance Projects | p. 27 |
Syndromic Surveillance for Special Events | p. 29 |
Syndromic Surveillance Data Sources and Collection Strategies | p. 33 |
Data Sources for Public Health Syndromic Surveillance | p. 33 |
Comparison of Data Sources | p. 37 |
Standardized Vocabularies | p. 42 |
Existing Data Standards Used in Syndromic Surveillance | p. 43 |
Data Entry and Data Transmission | p. 46 |
Data Entry Approaches | p. 47 |
Secure Data Transmission | p. 47 |
Data Analysis and Outbreak Detection | p. 49 |
Syndrome Classification | p. 49 |
Syndrome Classification Approaches | p. 51 |
Performance of Syndrome Classification Approaches | p. 54 |
A Taxonomy of Outbreak Detection Methods | p. 55 |
Retrospective vs. Prospective Syndromic Surveillance | p. 55 |
Temporal, Spatial, and Spatial-Temporal Outbreak Detection Methods | p. 56 |
Temporal Data Analysis | p. 61 |
Statistical Process Control (SPC)-Based Anomaly Detection | p. 61 |
Serfling Statistic | p. 62 |
Autoregressive Model-Based Anomaly Detection | p. 63 |
Hidden Markov Model (HMM)-Based Models | p. 64 |
Spatial Data Analysis | p. 65 |
Generalized Linear Mixed Models and Smart Algorithm | p. 66 |
Spatial Scan Statistic and Its Variations | p. 67 |
Risk-Adjusted Support Vector Clustering (RSVC) Algorithm | p. 69 |
Spatial-Temporal Data Analysis | p. 69 |
Rule-Based Anomaly Detection with Bayesian Network Modeling | p. 69 |
Population-Wide Anomaly Detection and Assessment (PANDA) | p. 70 |
Monitoring Multiple Data Streams | p. 70 |
Special Events Surveillance | p. 71 |
Summary of Data Analysis Process for Syndromic Surveillance | p. 72 |
Data Visualization, Information Dissemination, and Alerting | p. 73 |
Scope and Taxonomy | p. 74 |
Visual Information Display | p. 74 |
Visualization of Time-Series Data | p. 75 |
Visualization of Spatial Information | p. 77 |
GIS for Disease Event Visualization | p. 79 |
Spatial-Temporal Disease Modeling and Other Visualization Examples | p. 83 |
Interactive Visual Data Exploration | p. 84 |
Summary of Data Visualization in Syndromic Surveillance Applications | p. 85 |
Information Dissemination and Reporting | p. 86 |
System Assessment and Evaluation | p. 89 |
Syndromic Surveillance System Evaluation Framework | p. 90 |
Evaluation of Outbreak Detection Algorithms | p. 93 |
Evaluation Methodology | p. 93 |
Real Data Testing | p. 91 |
Fully Synthetic Data Testing | p. 92 |
Semisynthetic Data Testing | p. 94 |
Evaluation Metrics for Outbreak Detection Algorithms | p. 95 |
Summary of Representative Evaluation Studies | p. 98 |
Evaluation of Data Collection and Information Dissemination Components | p. 101 |
Assessment of Interface Features and System Usability | p. 101 |
System Usability Evaluation Methodology | p. 101 |
System Usability Evaluation Metrics | p. 102 |
Summary of System Usability Evaluation Studies | p. 102 |
Summary and Discussion | p. 103 |
Syndromic Surveillance System Case Studies | |
BioSense | p. 109 |
BioSense Data Collection and Preprocessing | p. 132 |
BioSense Data Analysis | p. 113 |
BioSense Data Visualization, Information Dissemination, and Reporting | p. 114 |
Case Study: Monitoring Health Effects of Wildfires Using BioSense | p. 116 |
Further Readings | p. 119 |
Rods | p. 121 |
RODS Data Collection | p. 122 |
RODS Data Analysis | p. 124 |
RODS Visualization, Information Dissemination, and Reporting | p. 126 |
Case Study: Syndromic Surveillance with RODS for the 2002 Winter Olympics | p. 128 |
Further Readings | p. 131 |
BioPortal | p. 133 |
BioPortal Data Collection | p. 135 |
BioPortal Data Analysis | p. 135 |
BioPortal Visualization, Information Dissemination, and Reporting | p. 136 |
Case Study: Foot-and-Mouth Disease Situational Awareness | p. 142 |
Further Readings | p. 144 |
Essence | p. 147 |
Essence Data Collection | p. 149 |
Essence Data Analysis and System Evaluation | p. 150 |
Essence Interface, Information Dissemination, and Reporting | p. 152 |
Further Readings | p. 155 |
New York City Syndromic Surveillance Systems | p. 157 |
NYC ED Syndromic Surveillance System Data Collection | p. 158 |
NYC ED Syndromic Surveillance System Data Analysis and Field Investigations | p. 159 |
NYC ED Syndromic Surveillance System Visualization, Information Dissemination, and Reporting | p. 360 |
Case Study: Respiratory Illness Surveillance Using Multiple Syndromic Systems in New York City | p. 162 |
Further Readings | p. 164 |
Ears | p. 167 |
Ears Data Collection and Data Preprocessing | p. 168 |
Key Ears Aberration Detection Methods | p. 169 |
Ears Visualization, Information Dissemination, and Reporting | p. 171 |
Case Study: PostHurricane Public Health Surveillance with EARS. | p. 173 |
Further Readings | p. 174 |
Argus | p. 177 |
Health Map | p. 183 |
Challenges and Future Directions | p. 187 |
Challenges for Syndromic Surveillance Research | p. 187 |
Summary and Future Directions | p. 188 |
References | p. 191 |
Subject Index | p. 207 |
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