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9780198540403

Infectious Diseases of Humans Dynamics and Control

by ;
  • ISBN13:

    9780198540403

  • ISBN10:

    019854040X

  • Edition: Reprint
  • Format: Paperback
  • Copyright: 1992-09-24
  • Publisher: Oxford University Press

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Summary

This book deals with infectious diseases -- viral, bacterial, protozoan and helminth -- in terms of the dynamics of their interaction with host populations. The book combines mathematical models with extensive use of epidemiological and other data. This analytic framework is highly useful for the evaluation of public health strategies aimed at controlling or eradicating particular infections. Such a framework is increasingly important in light of the widespread concern for primary health care programs aimed at such diseases as measles, malaria, river blindness, sleeping sickness, and schistosomiasis, and the advent of AIDS/HIV and other emerging viruses. Throughout the book, the mathematics is used as a tool for thinking clearly about fundamental and applied problems having to do with infectious diseases. The book is divided into two parts, one dealing with microparasites (viruses, bacteria and protozoans) and the other with macroparasites (helminths and parasitic arthropods). Each part begins with simple models, developed in a biologically intuitive way, and then goes on to develop more complicated and realistic models as tools for public health planning. The book synthesizes previous work in this rapidly growing field (much of which is scattered between the ecological and the medical literature) with a good deal of new material.

Table of Contents

Introduction
A Framework for Discussing the Population Biology of Infectious Diseases
Microparasites
Biology of the Host-Microparasite Associations
The Basic Model: Statics
Static Aspects of Eradication and Control
The Basic Model: Dynamics
Dynamic Aspects of Eradication and Control
Beyond the Basic Model: Empirical Evidence of Inhomogeneous Mixing
Age-Related Transmission Rates
Genetic Heterogeneity
Social Heterogeneity and Sexually Transmitted Diseases
Spatial and Other Kinds of Heterogeneity
Endemic Infections in Developing Countries
Indirectly Transmitted Microparasites
Macroparasites
Biology of Host Macroparasite Associations
The Basic Model: Statics
The Basic Model: Dynamics
Acquired Immunity
Heterogeneity within the Human Community
Indirectly Transmitted Helminths
Experimental Epidemiology
Parasites, Genetic Variability, and Drug Resistance
The Ecology and Genetics of Host-Parasite Associations
Table of Contents provided by Publisher. All Rights Reserved.

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