Inflammatory Bowel Disease

by Targan, Stephan R.; Shanahan, Fergus; Karp, Loren C.

• ISBN13: 9780387258072
• ISBN10: 0387258078
• Edition: 2nd
• Format: Paperback
• Copyright: 2005-05-17
• Publisher: Springer Verlag

Summary

Inflammatory Bowel Disease: From Bench to Bedside is a detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders are explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.

Table of Contents

Preface

The Laboratory Bench

Introduction: Inflammatory Bowel Diseases: From Bench to Bedside

The Changing Faces of Crohn's Disease and Ulcerative Colitis

Genetics of Inflammatory Bowel Disease

Experimental Mouse Models of Inflammatory Bowel Disease: New Insights into Pathogenic Mechanisms

The Normal Intestinal Mucosa - A State of `Controlled' Inflammation

The Lymphocyte/ Epithelial/ Bacterial Interface

The Mucosal Inflammatory Response I: Cytokines and Chemokines

Role of the Microcirulation in Chronic Gut Inflammation

Remission, Relapse, Intestinal Healing and Repair

Antibodies in the Exploration of Inflammatory Bowel Disease Pathogenesis and Disease Stratification

Pathophysiology of Inflammatory Bowel Disease: The Effect of Inflammation on Intestinal Function

Systemic Consequences of Intestinal Inflammation

The Bedside

Understanding Symptoms and Signs in Inflammatory Bowel Diseases

Clinical Course and Complications of Ulcerative Colitis and Ulcerative Proctitis

Clinical Features and Complications of Crohn's Disease

Mechanisms of Systemic Inflammation Associated with Intestinal Injury

Pathology of Inflammatory Bowel Diseases: A Critical Appraisal in Diagnosis and Management

An Endoscopic and Histologic Perspective of Diagnosis: When, Where and What to Do

Radiologic (Radiographic) and Imaging Features of Ulcerative Colitis and Crohn's Disease

New Diagnostic Approaches in Inflammatory Bowel Disease

Differential Diagnosis of Colitis

"Disease Management" in Chronic Medical Conditions

Pharmacoeconomics and Inflammatory Bowel Disease

Measuring Quality of Life in Inflammatory Bowel Disease

Additional Chapters

Back to the Laboratory Bench

Epilogue

Table of Contents provided by Publisher. All Rights Reserved.