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ROBERT P. LISAK, FAAN, FRCP (E), FANAParker Webber Chair in Neurology, Professor of Neurology, Professor of Immunology and Microbiology, Wayne State University School of Medicine; Attending Neurologist, Detroit Medical Center, Detroit, MI, USA
DANIEL D. TRUONG MD FAANThe Truong Neuroscience Institute, Orange Coast Memorial Medical Center, Fountain Valley, CA, USA; Professor, University California Riverside, Riverside, CA, USA
WILLIAM M. CARROLL MBBS MD FRACP FRCP(E)Clinical Professor of Neurology, Western Australian Research Institute, University of Western Australia, Australia
ROONGROJ BHIDAYASIRI MD FRCPDirector, Chulalongkorn Comprehensive Movement Disorders CenterChulalongkorn University Hospital, Bangkok, Thailand;University of California at Los Angeles, Los Angeles, CA, USA
List of contributors
Foreword
Endorsement from the World Federation of Neurology
Preface
Part 1 Vascular
1 Overview of StrokeChristopher Li-Hsian Chen, Chung Y. Hsu
2 Ischemic Stroke and Transient Events, TIALidia Yamada, Shelly Ozark, Bruce Ovbiagele
3 Atherothrombotic DiseaseNijasri C. Suwanwela
4 Occlusion Disease of Small Penetrating ArteriesMarie Dagonnier, Takeshi Iwanaga, Hock L. Teoh, Jorge A. Zavala, Geoffrey A. Donann
5 Ischemic White Matter Disease (Binswanger’s disease)Saltanat U. Kamenova, Aida M. Kondybayeva, Assiya Akanova
6 Brain EmbolismBernard P. L. Chan, N. Venketasubramanian, Chung Y. Hsu
7 Systemic Hypotensive Injury (Border Zone Infarction)Thomas W. Leung
8 Dissection of the Cervicocerebral ArteriesNijasri C. Suwanwela
9 Coagulation DisordersKay Sin Tan
10 Hemorrhagic StrokesAnna Katharina Flügel, Thorsten Steiner, Josef Schill, Nauman Jahangir, Morad Chughtai, Mushtaq H. Qureshi, Adnan I. Qureshi
11 Strokes in Children and Young AdultsAlfred Lindner, Ute Berweiler
12 Other Cerebrovascular SyndromesDavid J. Blacker
13 Cerebral Venous DiseasePatrick W. Carney, Stephen M. Davis
14 Spinal Cord StrokesRohini Bhole, Louis R. Caplan
Part 2 Disorders of Cerebrovacular Autonomic Control
15 Reversible Cerebral Vasoconstrictive Syndrome (RCVS)Shih-Pin Chen, Shuu-Jiun Wang
16 Posterior Reversible Encephalopathy Syndrome (PRES)Pratik Bhattacharya
Part 3 The Vasculitides
Inflammatory vasculopathy
17 Extracranial and Intracranial Granulomatous Arteritis (Giant cell arteritis)Gregory P. Van Stavern
18 Intracranial granulomatous Arteritis (primary Angiitis of the CNS)/ Idiopathic CNS VasculitisDonald Silberberg
19 Takayasu’s ArteritisYasuhisa Kitagawa
20 Polyarteritis Nodosa, Churg-Strauss and Overlap Vasculitis SyndromeArnold I. Levinson, Robert P Lisak
21 Granulomatosis with Polyangiitis (GPS)Gerard Said
22 Cerebrovascular Disease Associated with Antiphospholipid AntibodyAdrian Marchidann, Steven R. Levine
23 Thromboangiitis Obliterans – Buerger diseaseKumar Rajamani
24 Susac’s diseaseRachel E. Ventura, Steven L. Galetta
Part 4 Inflammatory Vasculopathies
25 SLE, Rheumatoid arthritis, Sjögren’s syndromeMarc Gotkine, Oded Abramsky
26 Progressive Systemic SclerosisHo Jin Kim, Jae-Won Hyun
27 Mixed connective tissue disordersHo Jin Kim, Jae-Won Hyun
28 Micro vasculitides and Behcet’s diseaseUgur Uygunoglu, Sabahattin Saip, Aksel Siva
29 SarcoidosisBarney J. Stern
30 Autoimmune Encephalitis with Neuronal Cell Surface AntibodiesJosep Dalmau, Myrna R. Rosenfeld
Part 5 Paroxysmal disorders
31 Epilepsy OverviewAndres M. Kanner, Barbara E. Swartz
32 Cryptogenic and Symptomatic Generalized Epilepsies and SyndromesMarco T. Medina, Antonio V. Delgado-Escueta, Luis C. Rodríguez Salinas, Marco Medina-Montoya, Barbara E Swartz
33 Genetic (primary) Idiopathic Generalized EpilepsiesAfawi Zaid, Altynshash Jaxybayeva
34 Localization Related EpilepsiesHirokazu Oguni, Chrysostomos P. Panayiotopoulos
35 Neurodiagnostic Tools for the Paroxysmal DisordersBarbara E. Swartz
36 Neuropharmacology of Antiepileptic DrugsPaul B. Pritchard, III
37 Surgical and Other TreatmentIvan Rektor, Barbara E. Swartz
Part 6 Dementia
38 Dementia OverviewMurray Grossman
39 Mild cognitive impairment to include amnestic mild cognitive impairment and Alzheimer’s diseaseDavid Wolk, Sanjeev Vaishnavi
40 Parkinson's Dementia, Lewy Body Disease and Other SynucleinopathiesIrena Rektorová, Marek Balá?, Robert Rusina, Radoslav Matìj
41 Specific Vascular SyndromesElka Stefanova, Vladimir Kostiæ
42 Vascular cognitive ImpairmentElka Stefanova, Vladimir Kostiæ
43 Frontotemporal dementiaKatya Rascovsky, Diana Matallana
44 Progressive Supranuclear Palsy, Corticobasal Syndrome and Other TauopathiesDavid J. Irwin
45 Amyotrophic Lateral Sclerosis and Other TDP-43 ProteinopathiesAlbert C. Ludolph
46 Metabolic, toxic, infectious, inflammatory and other dementiasJohn M. Ringman, Arousiak Varpetian, Yu-Wei Lin
Part 7 Movement Disorders
47 Movement disorders: An overviewRoongroj Bhidayasiri, Jirada Sringean, Daniel D. Truong
48 TremorJan Raethjen, Günther Deuschl
49 ParkinsonismDronacharya Lamichhane, Lisa M. Shulman
50 Parkinson’s diseaseDaniel D. Truong, Roongroj Bhidayasiri
51 DystoniaStanley Fahn
52 Chorea and related disordersRoongroj Bhidayasiri, Onanong Jitkritsadakul, Daniel D. Truong
53 MyoclonusJohn N. Caviness, Daniel D. Truong
54 Tics and Tourette syndromeValerie Suski, Mark Stacy
55 AtaxiaSergey N. Illarioshkin
56 Drug induced movement disordersRick Stell
57 Paroxysmal movement disordersSopio Sopromadze, Alexander Tsiskaridze
Part 8 Infectious diseases
Bacterial infections
58 Acute bacterial meningitisSudesh Prabhakar
59 Brain abscessGagandeep Singh
60 Subdural empyemaSandi Lam, Eric Momin
61 Epidural abscessSandi Lam, Humphrey Okechi, Jared Fridley
62 Intracranial septic thrombophlebitisIsmail A. Khatri, Mohammad Wasay
63 Encephalitis due to bacterial infectionsKaren L. Roos, Jennifer Durphy
Mycobacterial infections
64 Mycobacterium tuberculosis and aviumEinar P. Wilder-Smith
65 LeprosyMinh Le, Minh Hoang Van
Spirochetal infections
66 NeurosyphilisJonathan Carr
67 Lyme diseasePatricia K. Coyle
Protozoan diseases
68 Introduction to protozoans of the central nervous systemMarylou V. Solbrig
69 Amoebic disease of the central nervous systemMelanie Walker
70 Toxoplasmosis of the central nervous systemMarylou V. Solbrig
71 Cerebral malariaPolrat Wilairatana, Srivicha Krudsood, Noppadon Tangpukdee
72 TrypanosomiasisFrancisco Javier Carod-Artal
Helminthic
73 CestodesOscar H. Del Brutto
74 Trematodes: schistosomiasisManjari Tripathi
75 NematodesManjari Tripathi
Other infection
76 Fungal infections of the central nervous systemThomas Cesario
77 Rickettsial diseaseKelly J Baldwin, Narendra Rathi
Part 9 Prion diseases and Neurovirology
78 Prion DisordersEllen Gelpi, Herbert Budka
79 Acute and recurrent viral meningitisLarry E. Davis
80 Acute viral encephalitisHeng Thay Chong, Chong Tin Tan
81 Neurologic complications of human herpes virus infectionsDon Gilden, Maria A. Nagel
82 Chronic viral diseases of the CNSMaria A. Nagel, Don Gilden
83 Progressive multifocal leukoencephalopathy, PMLSalim Chahin, Thomas Weber, Joseph R. Berger
HIV and the Nervous System
84 Biology of the HIV Virus and overview of AIDSAlexandros C. Tselis
85 HIV encephalitis and myelopathyGirish Modi, Kapila Hari, Andre Mochan
86 Neuromuscular complications of HIVDavid M. Simpson, Kara Stavros
87 Opportunistic Infections in HIV Positive Subjects and AIDS patientsB. J. Brew, A. Laffan
88 Neurologic Complications of HTLV-1Abelardo Q-C Araujo, Marco A. Lima, Marcus Tulius Silva
Part 10 Demyelinating Disorders
89 Multiple sclerosisRobert P. Lisak, Jun-Ichi Kira
90 Multiple sclerosis in childrenSarah E. Hopkins, Yael Hacohen, Sona Narula, Brenda L Banwell
91 Neuromyelitis opticaWilliam M. Carroll
92 Acute disseminated encephalomyelitisSona Narula, Sarah E. Hopkins, Yael Hacohen, and Brenda Banwell
93 Isolated inflammatory demyelinating CNS syndromesErnest Willoughby
94 Osmotic demyelination syndromesOvidiu-Alexandru Bajenaru
95 Concentric sclerosisTakeshi Tabira
Part 11 Specific toxicities and deficiencies
96 ToxicologyChin-Chang Huang, Nai-Shin Chu
97 Alcohol related neurological disordersYuri Alekseenko
98 Vitamin DeficienciesJacques Serratrice, Volodymyr Golyk
99 Starvation, Strachan syndrome and postgastroplasty syndromeIvan Milanov, Vesselina Grozeva
Part 12 Peripheral Neuropathies
100 Peripheral Neuropathies overviewFriedhelm Sandbrink
101 Hereditary neuropathiesLiying Cui, Mingsheng Liu
102 Acquired NeuropathiesFriedhelm Sandbrink
103 PlexopathiesFriedhelm Sandbrink
Part 13 Neuromuscular DisordersHereditary Neuromuscular DisordersDegenerative upper and lower motor neuron disorders
104 Amyotrophic Lateral Sclerosis (ALS)Björn Oskarsson, Nanette Joyce, Steven P. Ringel
105 Progressive Muscular Atrophy (PMA)James Ha, Steven P. Ringel, Björn Oskarsson
106 Primary Lateral Sclerosis (PLS)Nanette Joyce, Björn Oskarsson, Yvonne D. Rollins, Steven P. Ringel
107 Hereditary spastic paraplegiaIldefonso Rodríguez-Leyva
108 Spinal muscular atrophySabine Rudnik-Schöneborn, Klaus Zerres
109 Post-polio syndromeNils Erik Gilhus
Degenerative Muscle Disorders
110 Limb girdle muscular dystrophies (LGMD)A. J. van der Kooi, M. de Visser
111 DystrophinopathiesChiara S. M. Straathofa, Marianne de Visserb
112 Facioscapulohumeral dystrophy (FSHD)George W. Padberg
113 Myotonic disordersGiovanni Meola, Rosanna Cardani
114 Oculopharyngeal Muscular Dystrophy (OPMD)Luis A. Chui, Tahseen Mozaffar, Namita A. Goyal
115 Emery Dreifuss and other laminopathiesMalcolm Rabie, Yoram Nevo
116 Muscle channelopathiesKaren Suetterlin, Michael G. Hanna
117 Congenital dystrophies and myopathiesYoung-Chul Choi
118 Congenital myasthenic syndromes (CMS)Angela Abicht, Ulrike Schara
119 Distal myopathiesPhillipa J. Lamont, Nigel G. Laing
Acquired Neuromuscular Disorders
120 PolymyositisMarinos C. Dalakas
121 DermatomyositisMarinos C. Dalakas
122 Inclusion body myositis (IBM)Merrilee Needham, Frank L. Mastaglia
123 Immune mediated inflammatory myopathiesWerner Stenzel, Hans-Hilmar Goebel, Olivier Benveniste, Yves Allenbach
124 Toxic myopathiesStefen Brady, David Hilton-Jones
125 Critical illness neuromuscular disordersNicola Latronico, Frank A. Rasulo
126 Exercise intolerance and myoglobinuriaJohn Vissing
127 Muscle crampsKimiyoshi Arimura, Raymond L. Rosales
128 Myasthenia gravisRichard A. Lewis
129 LEMSEmilia Kerty
130 NMJ disorders caused by drugs and toxinsZohar Argov
Part 14 Neurogenetic
131 NeurogeneticKaren P. Frei, Janice Fuentes
Part 15 Neurootology
132 NeurootologyKevin A. Kerber
Part 16 Neuroophthalmology
133 NeuroophthalmologyAnuchit Poonyathalang
Part 17 Neuro-oncology
134 Neuro-oncology overviewMarc C. Chamberlain
Glial tumors
135 High grade astrocytomasOlivier-L Chinot, Marc C. Chamberlain
136 Low grade astrocytomasM.J. van den Bent
137 Low grade and anaplastic oligodendrogliomaSergio Cabrera, Catherine Maurice, Warren P. Mason
138 Brain stem gliomaIra J. Dunkel, Mark M. Souweidane
139 Intracranial ependymomaMarc C. Chamberlain
Non-glial tumors
140 Nerve sheath tumorsNathan J. Ranalli, Zarina S. Ali, Gregory G. Heuer, Eric L. Zager
141 MeningiomasJeffrey Raizer, Simran Singh
142 MedulloblastomaAlba A. Brandes, Regina I. Jakacki, Enrico Franceschi
143 Primary central nervous system lymphoma (PCNSL)Deborah T. Blumenthal, Idan Ben-Horin
Metastatic tumors
144 Brain metastasesBabita Jyoti, Farida Balkhi Alam, Silvia Hofer, Michael Brada
145 Leptomeningeal metastasesEmilie Le Rhun, Sophie Taillibert, Marc C. Chamberlain
146 Spinal epidural metastasesRoberta Rudà, Riccardo Soffietti
Neurologic complications of systemic cancer147 General approach to the diagnosis and treatment of paraneoplastic neurological disordersMyrna R. Rosenfeld, Josep Dalmau
Part 18 Sleep disorders
148 InsomniaDelwyn J. Bartlett, Colin A. Espie
Primary disorders of daytime somnolence
149 NarcolepsyMarcel Hungs
150 Idiopathic hypersomniaMarcel Hungs
151 Obstructive Sleep ApneaJanesh Patel, Christian Guilleminault
152 Restless Leg syndrome and Periodic Limb Movement DisordersBirgit Högl, Birgit Frauscher, Claudio Podesta
153 Circadian sleep disordersSergio Tufik, Lia R .A. Bittencourt, Monica L. Andersen
Parasomnias
154 Arousal disordersLi Ling Lim
155 REM Sleep Behavioral DisordersLi Ling Lim
156 Hypnogenic paroxysmal DystoniaCynthia L. Comella
157 Sleep abnormalities in Neurological DisordersMargaret Park, Cynthia L. Comella
Part 19 Spinal cord
158 Spinal cord disordersDavid B. Vodušek, Miran Jeromel, Simon Podnar
159 Ischemic and congestive myelopathiesSimon Podnar, Miran Jeromel, David B. Vodušek
160 SyringomyeliaAlla Guekht
Part 20 Pediatric neurology
161 Neonatal neurologyMary Payne, Ann Tilton
162 Neurodevelopmental disordersAdam L. Numis, Raman Sankar
163 Floppy infant syndromeJong-Hee Chae, Anna Cho
164 Storage disordersJeffrey J. Ekstrand, Jason T. Lerner, Raman Sankar
165 Fatty acid oxidation disordersThomas Wieser
166 Disorders of amino acid, organic acid, and ammonia metabolismStephen Cederbaum
167 Pediatric neurotransmitter diseasesStephen Deputy
168 Mitochondrial encephalomyopathiesStacey K. H. Tay, Caterina Garone, Salvatore DiMauro
169 Disorders resulting from transportersAnna Czlonkowska, David Gloss, Tomasz Litwin
170 The porphyriasF. J. E. Vajda
Part 21 CNS Trauma, Pain and Headache
171 Traumatic brain injuryChristopher C. Giza
172 Spinal InjuryEnver I. Bogdanov, Aisylu T. Faizutdinova
173 Whiplash injuryAnthony Ciabarra
174 Decompression sicknessAndreas Koch, Günther Deuschl
175 PainGuillermo García-Ramos, Bernardo Cacho-Díaz, Bruno Estañol-Vidal
176 HeadacheStephen D. Silberstein
177 Facial and neck painKammant Phanthumchinda
178 Chronic Fatigue SyndromeJasem Yousef Al-Hashel
179 FibromyalgiaSaeed Bohlega, Hussam Abou Al-Shaar
Index
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