International Review of Cell & Molecular Biology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. * Authored by some of the foremost scientists in the field * Provides up-to-date information and directions for future research * Valuable reference material for advanced undergraduates, graduate students and professional scientists

Contributors	p. ix
Cytokinin Signaling During Root Development	p. 1
Introduction	p. 2
The Two-Component Signal Transduction Pathway	p. 4
The Role of Cytokinin Signaling Specific to Certain Developmental Pathways	p. 22
Concluding Remarks	p. 38
References	p. 39
Live-Cell Imaging in the Study of Neurodegeneration	p. 49
Introduction	p. 51
Live Imaging of Cell Lines	p. 54
Live Imaging of Primary Neurons	p. 64
Live Imaging of Organotypic Cultures	p. 71
Live Imaging of Animals	p. 84
Multiphoton Versus One-Photon Microscopy-Potential and Limitation	p. 91
Combined Approaches	p. 92
Concluding Remarks	p. 94
Acknowledgment	p. 95
References	p. 95
Interactions Between Heparan Sulfate and Proteins-Design and Functional Implications	p. 105
Introduction	p. 106
HS Proteoglycans	p. 107
Structure and Biosynthesis of HS	p. 109
Interactions of HS with Proteins	p. 120
Interference with HS Function	p. 129
Is There a "Sulfation Code"?	p. 134
HS and Disease	p. 136
Concluding Remarks	p. 142
References	p. 143
Fibroblasts-A Diverse Population at the Center of It All	p. 161
Introduction	p. 162
General Characteristics of Fibroblasts	p. 163
Fibroblast Diversity	p. 169
Functional Significance of Fibroblast Heterogeneity	p. 176
Fibroblast Interactions with Epithelial Cells	p. 179
Fibroblasts, the Architects of Tissues	p. 189
Thy-1+ and Thy-1- Subpopulations of Fibroblasts	p. 194
Fibroblasts as Sentinel Cells	p. 196
Fibroblasts in Aging	p. 198
Concluding Remarks	p. 202
Acknowledgments	p. 202
References	p. 202
Imprinting and Extraembryonic Tissues-Mom Takes Control	p. 215
Introduction	p. 216
Genomic Imprinting-What is It?	p. 217
Genomic Imprinting as a Maternal Effect	p. 220
Placenta as Target of Imprinting	p. 225
Conclusions	p. 246
Acknowledgments	p. 246
References	p. 247
Cell and Molecular Biology of ATP-Binding Cassette Proteins in Plants	p. 263
Introduction	p. 264
ABC Proteins Localized to Plasma Membranes	p. 265
ABC Proteins Localized to Other Organelles	p. 283
Soluble-Type ABC Proteins in Plants	p. 290
Conclusion	p. 291
References	p. 292
Cell and Molecular Biology of the Fastest Myosins	p. 301
Introduction	p. 302
In Vitro Motility	p. 303
Myosins in Plants	p. 305
The Molecular Structure of Plant Myosins	p. 311
Three-Dimensional Structure of Chara Myosin	p. 321
Mechanism of Chara Myosin Motility	p. 328
Concluding Remarks	p. 336
Acknowledgments	p. 338
References	p. 338
Index	p. 349
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