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Olivier Goulet, MD, PhD Pediatric Gastroenterology-Hepatology and Nutrition, Reference Center for Rare Digestive Diseases, Integrated Program of Intestinal Failure, Home Parenteral Nutrition and Intestinal Transplantation, University of Paris-Descartes, Necker Hospital, Paris, France.
Eamonn M.M. Quigley, MD, FRCP, FACP, FACG, FRCPI is Professor of Medicine and Human Physiology and Head of the Medical School at the National University of Ireland (NUI), Cork. He also serves as Adjunct Professor of Medicine and Physiology at the University of Nebraska Medical Center in Omaha, USA. He is Editor-in-Chief of the American Journal of Gastroenterology and Vice-President of the World Organization of Gastroenterology (OMGE - Organisation Mondiale de Gastroentérologie). His major research interests are in the areas of motility, functional gastrointestinal disorders and gastrointestinal dysfunction in systemic disease. He has published over 400 original papers, reviews, editorials and book chapters and has received numerous awards from universities and societies worldwide.
Kelly A. Tappenden, PhD, RD is Associate Professor of Nutrition and Gastrointestinal Physiology in the Division of Nutritional Sciences at the University of Illinois at Urbana-Champaign, USA. Professor Tappenden recently received the 2005 American Society of Parenteral and Enteral Nutrition Dudrick Research Scholar Award and the 2004 College of Agricultural, Consumer and Environmental Sciences Faculty Award for Excellence in Research. Professor Tappenden’s research interests include the regulation of small intestinal function by various nutrients and gastrointestinal-specific pepides. Her recent publications are featured in the Journal of Parenteral and Enteral Nutrition, Journal of Pediatric Gastroenterology and Nutrition and Journal of Nutrition. In addition to her academic research, Professor Tappenden is also a Registered Dietician, having completed clinical training at the Misericordia Hospital in Edmonton, Alberta.
List of Contributors | p. viii |
Foreword | p. xiii |
Preface | p. xvii |
Abbreviations | p. xix |
Introduction | |
The History of Intestinal Failure and Transplantation | p. 3 |
Intestinal Physiology and Immunology | |
Intestinal Morphology, Intestinal Regeneration and the Promise of Tissue Engineering | p. 13 |
Basic Physiology of Motility, Absorption and Secretion | p. 20 |
Immunology of the Small Intestine | p. 33 |
Intestinal Adaptation: The Biology of the Intestinal Response to Resection and Disease | p. 45 |
Intestinal Failure: Definition and Pathophysiology | |
Intestinal Failure: Definitions and Classifications | p. 57 |
Causes of Intestinal Failure in the Newborn | p. 66 |
Congenital Enteropathies Causing Permanent Intestinal Failure | p. 77 |
Causes of Intestinal Failure in the Adult | p. 88 |
Intestinal Failure Related to Bariatric Surgery | p. 93 |
Inflammatory Bowel Disease and the Short Bowel Syndrome | p. 99 |
Motility Disorders | p. 107 |
Assessment and General Management of Intestinal Failure | |
Assessment of Intestinal Failure Patients | p. 117 |
Guidelines for Home Parenteral Nutrition Support in Chronic Intestinal Failure Patients | p. 122 |
Home Parenteral Nutrition: Complications, Survival, Costs and Quality of Life | p. 130 |
Vascular Access, Including Complications | p. 142 |
Enteral Support for Children with Intestinal Failure | p. 151 |
The Use of Enteral Nutrition in the Adult with Intestinal Failure | p. 160 |
The Enteric Flora in Intestinal Failure: Small Intestinal Bacterial Overgrowth and Gut-Derived Sepsis | p. 167 |
Management of Complex Fluid and Electrolyte Disturbances | p. 185 |
Intestinal Failure-Associated Liver Disease | p. 191 |
Psychiatric Issues in the Assessment of the Patient with Intestinal Failure | p. 201 |
Munchausen Syndrome by Proxy | p. 206 |
Pharmacological Approaches to Intestinal Failure | |
Luminal Nutrient Factors in Intestinal Adaptation and Their Use in Therapy | p. 215 |
The Role of Humoral Factors in Intestinal Adaptation | p. 223 |
Autologous Reconstruction of the GI Tract | |
Autologous Reconstruction of the GI Tract | p. 231 |
Organ Replacement Therapy for Intestinal Failure | |
Intestinal Transplantation: Indications and Patient Selection | p. 245 |
Isolated Small Bowel Transplantation and Combined Liver-Small Bowel Transplantation | p. 254 |
Living Donor Intestinal Transplantation | p. 262 |
Isolated Liver Transplantation for Intestinal Failure-Associated Liver Disease | p. 270 |
Preservation of the Intestine | p. 275 |
Immediate Postoperative Care of the Intestinal Transplant Recipient | p. 283 |
Surgical Complications of Intestinal Transplantation | p. 290 |
Infections in Small Bowel Transplant Recipients | p. 297 |
Immunosuppression after Intestinal Transplantation | p. 305 |
Immunology of Intestinal Allograft Rejection | p. 314 |
Histopathology of Intestinal Transplantation | p. 322 |
Long-Term Management of Intestinal Transplant Recipients | p. 331 |
Management of Posttransplant Lymphoproliferative Disease | p. 342 |
Results of Intestinal Transplantation | p. 349 |
Psychosocial Assessment and Management of the Transplant Patient/Family in Intestinal Transplantation | p. 357 |
Financial, Economic and Insurance Issues Pertaining to Intestinal Transplantation: When Is Too Much Not Enough? | p. 363 |
Index | p. 379 |
Table of Contents provided by Ingram. All Rights Reserved. |
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