Introduction to Computational Genomics: A Case Studies Approach

by Nello Cristianini , Matthew W. Hahn

• ISBN13: 9780521671910
• ISBN10: 0521671914
• eBook ISBN(s): 9780511258121, 9781316099469
• Format: Paperback
• Copyright: 2007-01-15
• Publisher: Cambridge University Press
• More Book Details

Summary

This readable and entertaining book provides a roadmap to navigate entry to the field of computational genomics in biology. It guides the reader through key achievements of bioinformatics, using a hands-on approach. Statistical sequence analysis, sequence alignment, hidden Markov models, gene and motif finding, and other topics are introduced in a rigorous yet accessible way.

Table of Contents

Prologue (In Praise of Cells)

1. The First Look at a Genome (Sequence Statistics)

2. All the Sequence's Men (Gene Finding)

3. All in the Family (Sequence Alignment)

4. The Boulevard of Broken Genes (Hidden Markov Models)

5. Are Neanderthals among Us? (Variation within and between sepcies)

6. Fighting HIV (Natural Selection at the Molecular Level)

7. SARS: A Post-Genomic Epidemic (Phylogenetic Analysis)

8. Welcome to the Hotel Chlamydia (Whole Genome Comparisons)

9. The Genomics of Wine-Making (Analysis of Gene Expression)

10. A Bed-Time Story (Identification of Regulatory Sequences)

A. The Appendix.