Acknowledgements | p. vii |
Preface to the first edition | p. viii |
Preface to the second edition | p. x |
Fundamentals of pharmacokinetics | p. 1 |
Introduction | p. 3 |
Absorption and distribution | p. 23 |
Metabolism and elimination | p. 44 |
Drug interactions | p. 61 |
Fundamentals of pharmacodynamics and toxicodynamics | p. 73 |
Drug receptors | p. 75 |
Dose-response relationship | p. 90 |
Drug toxicity | p. 101 |
Treating drug overdose | p. 137 |
Drugs that replace, cure, or treat symptoms | p. 147 |
Hormones | p. 149 |
Chemotherapeutic agents | p. 164 |
Drug treatment of symptoms: neuropharmacology and substance abuse | p. 181 |
Cardiovascular drugs | p. 241 |
Drug development | p. 265 |
Drug discovery by the pharmaceutical industry | p. 267 |
Pharmaceutical development of drugs and the FDA | p. 299 |
Animals in research | p. 316 |
Alternative medicine | p. 341 |
The History of drug abuse laws in the United States | p. 351 |
Glossary | p. 376 |
Answers to questions | p. 393 |
Index | p. 395 |
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