Introduction to Stereochemistry

by Mislow, Kurt

• ISBN13: 9780486425306
• ISBN10: 0486425304
• Format: Paperback
• Copyright: 2003-01-15
• Publisher: Dover Publications

Summary

Three-part introductory text reviews molecular architecture, relating empirical bonding geometries to hybridization of central carbon atom; classifies stereoisomers according to symmetry properties and to nature of their barriers; and explores conceptual basis of asymmetric syntheses and kinetic resolutions. Exercises with answers. 1965 edition.

Table of Contents

Preface to the Dover Edition	v
Preface	ix
Structure and Symmetry	1	(49)
Introduction	1	(5)
Bonding Geometries in Carbon Compounds	6	(7)
Bonding Orbitals in Carbon Compounds	13	(10)
Reflection Symmetry---Point Groups	23	(10)
Molecular Deformations and Strain Energies	33	(9)
Molecular Models	42	(4)
Exercises	46	(4)
Stereoisomerism	50	(69)
Classification of Structural Isomerism---Enantiomeric and Diastereomeric Relationships	50	(4)
Optical Activity	54	(13)
Diastereomers and Racemic Forms	67	(3)
Torsional Stereoisomerism	70	(16)
Stereoisomerism Resulting from Asymmetric Atoms---Designation of Configuration at Asymmetric Atoms	86	(11)
Torsional Stereoisomerism in the Presence of Asymmetric Atoms	97	(5)
Macromolecules	102	(8)
Topological Isomerism	110	(1)
Exercises	111	(8)
Separation and Configuration of Stereoisomers	119	(50)
Separation of Enantiomers and Diastereomers	119	(1)
Optical Activation	120	(2)
Asymmetric Synthesis and Kinetic Resolution	122	(19)
Absolute Configuration	141	(2)
Configurational Correlations by Chemical Methods	143	(6)
Configurational Correlations by Physical Methods	149	(12)
Exercises	161	(8)
Answers to Exercises	169	(6)
Bibliography	175	(4)
Index	179