Kinetic Models of Trace Element and Mineral Metabolism During Development

by Siva Subramanian; K. N.

• ISBN13: 9780849347368
• ISBN10: 084934736X
• Format: Hardcover
• Copyright: 1995-08-01
• Publisher: CRC Press

Summary

Kinetic models are becoming standard tools in the research of biological systems. They are used to represent hypotheses, analyze data, and design experiments to maximize the information obtained from a study. Kinetic Models of Trace Element and Mineral Metabolism During Development describes models for calcium, chromium, copper, iron, iodide, lead, mercury, selenium, zinc, and others in health and disease.

Table of Contents

Contributors
Preface
Use of Mineral Stable Isotopes in the Study of Nutrient Homeostasis During Human Pregnancy and Lactation	p. 1
Kinetic Overview: Modeling Calcium Metabolism in Pregnant and Lactating Cows	p. 11
Calcium Metabolism in Pregnancy and Lactation: An Individual Study	p. 29
Copper Metabolism in Dairy Cows: Development of a Model Based on a Stable Isotope Tracer	p. 37
Zinc Kinetics in Humans	p. 53
Stable Isotope Studies of Zinc Kinetic Metabolism in Infants	p. 65
Determination of Mineral Absorption by Very Low Birthweight Preterm Infants with the Stable Isotope Extrinsic Tag Approach	p. 73
Determination of Requirements	p. 95
Contributions of Mathematical Models to Understanding of Human Iodide Metabolism	p. 99
Zinc that Exchanges with Zinc in Plasma Within Two Days: Variation with Dietary Zinc	p. 117
Calcium Metabolism in Adolescents	p. 129
Stable Isotopes of Copper, Molybdenum, and Zinc Used Simultaneously for Kinetic Studies of their Metabolism	p. 133
Reference Values for Trace Elements in Human Clinical Specimens: With Special Reference to Biomonitoring and Specimen Suitability	p. 145
Studies of Calcium Metabolism in Children with Chronic Illnesses	p. 159
Historical Overview of Copper Kinetics	p. 171
Compartmental Analysis of Intestinal Iron Absorption and Mucosal Iron Kinetics	p. 187
Chromium (III) Metabolism in Diabetic Patients	p. 205
A Calcium-based Model of Human Lead Kinetics	p. 221
Some Constitutive Modifiers of the Kinetic and Dynamic Behavior of Non-essential Metals	p. 233
An Overview of Selenium Kinetics in Humans	p. 241
The Kinetics of Intravenously-Administered Inorganic Mercury in Humans	p. 265
Overview of Calcium Metabolic Dynamics	p. 281
Interpretation of Stable Isotope Studies of Calcium Absorption and Kinetics	p. 283
Calcium Homeostasis - an Old Problem Revisited	p. 291
Generalized Stochastic Compartmental Models of Calcium Metabolism	p. 305
Frequency Response of the Calcium Control System	p. 333
Regulation in Oscillatory Models	p. 341
Optimal Sampling for the Determination of Calcium Metabolism	p. 347
Determination of Bone Resorption	p. 355
Kinetic Models to Describe Populations: A Strategy for Summarizing the Results of Multiple Studies	p. 359
SAAMEASE: The Language of SAAM and CONSAM	p. 373
Index	p. 389
Appendix: Diskette containing CONSAM program and models
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