Language Lateralization and Psychosis

by Edited by Iris E. C. Sommer , René S. Kahn

• ISBN13: 9780521882842
• ISBN10: 0521882842
• Edition: 1st
• Format: Hardcover
• Copyright: 2009-05-11
• Publisher: Cambridge University Press

Summary

In 1861 Paul Broca discovered that, in most individuals, the left hemisphere of the brain is dominant for language. Taking language as an example, the first part of this book explains the normal development of bodily asymmetry and lateralization, its association with hand preference, genetic aspects, geographical differences and the influence of gender. The coverage then moves on to review the association between language lateralization and psychosis, describing findings in patients with schizophrenia to suggest the dominant hemisphere may fail to completely inhibit the language areas in the non-dominant half. The language allowed to 'release' from the right hemisphere can lead to psychotic symptoms including auditory verbal hallucinations and formal thought disorder. This book should be read by psychiatrists, neurologists and neuroscientists working in the field of psychosis and other brain scientists interested in laterality.

Table of Contents

List of contributors

Preface

Section

Asymmetry, Handedness and Language Lateralization

Molecular mechanisms establishing consistent left-right asymmetry during vertebrate embryogenesis

Cerebral lateralization in animal species Onur Gnntnrknn

The history and geography of human handedness

The association between hand preference and language lateralization Bianca Stubbe-Drager and Stefan Knecht

The genetic basis of lateralization Marian Annett

Language lateralization and handedness in twins; an argument against a genetic basis? Iris

Sex differences in handedness and language lateralization Iris

Language Lateralization and Psychosis

Hand-preference and population schizotypy Metten Somers, Iris

Functional imaging studies on language lateralization in schizophrenia patients Annick Razafimandimby, Olivier Ma za and Sonia Dollfus

The role of the right hemisphere for language in schizophrenia Alexander Rapp

Auditory verbal hallucinations and language lateralization Kelly Diederen and Iris

Language lateralization in patients with Formal Thought Disorder Carin Whitney and Tilo Kircher

LRRTM1: a maternally suppressed genetic effect on handedness and schizophrenia Clyde Francks

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