Late Effects of Childhood Cancer

by Wallace, Hamish; Green, Daniel

• ISBN13: 9780340808030
• ISBN10: 0340808039
• Format: Hardcover
• Copyright: 2004-04-15
• Publisher: Hodder Education Publishers

Summary

This definitive reference brings together all aspects of long-term effects of treatment for cancer during childhood in a single comprehensive volume. International in perspective, the book is structured according to complication rather than original site of malignancy for ease of reference. Topics covered include problems in the neurological system and special senses of sight and sound, cardiovascular, respiratory, gastrointestinal, urological and musculoskeletal complications, effects on the endocrine system and, in particular, future fertility, and secondary cancers. The book also reviews in detail the important issues of quality of life, prevention initiatives and strategies for long-term follow up. Key point summaries are included throughout, and the references are annotated to guide the reader quickly to seminal primary papers and key review articles. With an accessible and consistent approach throughout, Late Effects of Childhood Cancer is an invaluable source of information and guidance for pediatric oncologists, who need to keep fully informed in order to advise patients and their parents appropriately, and also for pediatric and adult endocrinologists, adult oncologists and other physicians to whom the patient with late effects may initially present.

Table of Contents

Contributors	ix
Foreword	xiii
Reference annotation	xv
1 Introduction	1	(2)
W Hamish B Wallace and Daniel M Green
2 Neurological and special senses	3	(52)
2a Long-term neurologic consequences of CNS therapy	5	(13)
Patricia K Duffner
2b Neuropsychological outcomes	18	(19)
Raymond K Mulhern, Sean Phipps and Holly White
2c Ocular complications	37	(12)
Michael Ober, Katherine Beaverson and David Abramson
2d Hearing impairment	49	(8)
Patricia D Shearer
3 Secondary primary cancers	55	(28)
3a Epidemiology	57	(13)
Smita Bhatia
3b Genetic susceptibility and familial cancer syndromes	70	(15)
Manuel Diezi and David Malkin
4 Cardiovascular complications	83	(31)
4a Cardiotoxicity caused by chemotherapy	85	(16)
Andrea S Hinkle, Cindy B Proukou, Sampada S Deshpande, Sarah A Duffy, Amy M Kozlowski, Carol A French and Steven E Lipshultz
4b Radiation damage	101	(22)
Gill A Levitt and Frank H Saran
5 Respiratory complications	114	(9)
Neyssa Marina, Christine Sharis and Nancy Tarbell
6 Urological complications	123	(22)
6a Renal damage	125	(13)
Roderick Skinner
6b Bladder complications	138	(9)
R Beverly Raney, Robin Zagone and Michael Ritchey
7 Gastrointestinal, hepatic and related complications	145	(42)
7a Body composition and obesity	147	(15)
John W Gregory and John J Reilly
7b The Tate effects of pediatric cancer treatment on the gastrointestinal tract	162	(8)
Nigel Meadows
7c Hepatic complications	170	(6)
Melissa M Hudson
7d Craniofacial development, teeth and salivary glands	176	(13)
Andrew L Sonis
8 Endocrine and fertility effects	187	(80)
8a Growth and neuroendocrine consequences	189	(23)
Ken H Darzy, Helena K Gleeson and Stephen M Shalet
8b Disturbance of the hypothalmic-pituitary thyroid axis	212	(13)
Helena A Spoudeas
8c Ovarian and uterine function and reproductive potential	225	(14)
Hilary OD Critchley, Angela B Thomson and W Hamish B Wallace
8d Testicular function	239	(18)
Angela B Thomson, W Hamish B Wallace and Charles Sklar
8e Pregnancy outcome	257	(12)
Daniel M Green
9 Musculoskeletal complications	267	(37)
9a Osteoporosis	269	(10)
Bernadette MD Brennan
9b Bone and collagen turnover	279	(14)
Patricia M Crofton
9c Limb salvage and spinal surgery	293	(11)
Hannah Morgan and Ernest U Conrad III
10 Bone marrow transplantation	304	(17)
Roderick Skinner and Alison D Leiper
11 Cutaneous complications	321	(12)
E Claire Benton and Michael J Tidman
12 Quality of life issues	333	(33)
12a Quality of life and body image	335	(15)
Christine Eiser
12b Legal issues: US perspective	350	(7)
Grace-Ann P Monaco and Gilbert Smith
12c Legal issues: UK perspective	357	(20)
Alexander McCall Smith
13 Healthy lifestyle and prevention strategies	366	(11)
Melissa M Hudson
14 Strategy for long-term follow up	377	(26)
14a US perspective	379	(13)
Kevin C Oeffinger
14b UK perspective	392	(11)
Christopher J H Kelnar and W Hamish B Wallace
Index	403