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9783642010743

Lead-seeking Approaches

by
  • ISBN13:

    9783642010743

  • ISBN10:

    3642010741

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2009-09-03
  • Publisher: Springer Verlag
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Supplemental Materials

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Summary

Christopher A. Lipinski: Overview of hit to lead: the medicinal chemist's role from HTS retest to lead optimization hand offJeff W. Paslay '_¢ John E. Morin '_¢ Richard K. Harrison: High Throughput Screening in the 21st CenturyJack Andrew Bikker '_¢ Lakshmi S.Narasimhan: Lead Discovery Using Virtual Screening Maurizio Pellecchia: NMR Spectroscopy in Fragment Based Drug DesignKevin D. Freeman-Cook '_¢ Daniel W. Kung: Hit Triage ' Medicinal Chemistry Strategies to Improve the Odds of Success in DiscoveryJohn W. Ellingboe '_¢ Adam M. Gilbert: Lead Identification

Table of Contents

Overview of Hit to Lead: The Medicinal Chemist's Role from HTS Retest to Lead Optimization Hand Offp. 1
High Throughput Screening in the Twenty-First Centuryp. 25
Lead Discovery Using Virtual Screeningp. 85
NMR Spectroscopy in Fragment Based Drug Designp. 125
Hit Triage: Medicinal Chemistry Strategies to Improve the Odds of Success in Discoveryp. 141
Lead Identificationp. 175
Indexp. 213
Table of Contents provided by Ingram. All Rights Reserved.

Supplemental Materials

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