Lipids and Cellular Membranes in Amyloid Diseases

by Jelinek, Raz

• ISBN13: 9783527328604
• ISBN10: 3527328602
• Edition: 1st
• Format: Hardcover
• Copyright: 2011-05-16
• Publisher: Wiley-VCH

Summary

This first book on the subject focuses on basic biochemical and biophysical facts, figures and methods, so as to be universally suited to the needs of basic and applied researchers in the biochemical, pharmaceutical and biomedical fields. As a result, the reader is brought up to date on the latest studies and models of amyloid formation.

Author Biography

Currently at the department of Chemistry at Ben Gurion University, Israel, Raz Jelinek obtained his BSc in chemistry from the Hebrew University of Jerusalem, Israel, and his PhD from the University of California, Berkeley. He was a Cancer Research Institute post-doctoral fellow at the University of Pennsylvania and a Visiting Professor at the Department of Chemical and Biomolecular Engineering at Johns Hopkins University. Professor Jelinek has over 90 scientific publications and 10 patents to his name, and has received several scientific awards, including the Roger-Siegel-Brown Award of the Israeli Academy of Science and the Ruth L. Kirschstein National Research Service Award of the National Institutes of Health, USA.

Table of Contents

Interactions of AlphaâÇôSynuclein with Lipids and Artificial Membranes Monitored by ESPIT Probes

Structural and Functional Insights Into AlphaâÇôSynuclein Lipid Interactions

Surfactants and Alcohols as Inducers of Protein Amyloid: Aggregation Chaperones or Membrane Simulators?

Interaction of hIAPP and its Precursors with Model and Biological Membranes

Amyloid Polymorphisms: Structural Basis and Significance in Biology and Molecular Medicine

Intracellular Amyloid Beta: A Modification to Amyloid Hypothesis in AlzheimerâDzs Disease

Lipid Rafts Play a Crucial Role in Protein Interactions and Intracellular Signaling Involved in Neuronal Preservation Against AlzheimerâDzs Disease

AlzheimerâDzs Disease as MembraneâÇôAssociated Enzymopathies of APP Secretases

Impaired Regulation of Glutamate Receptor Channels and Signaling Molecules by BetaâÇôAmyloid in AlzheimerâDzs Disease

Membrane Changes in BSE and Scapie

Interaction of Alzheimer Amyloid Peptide with Cell Surfaces and Artificial Membranes

Experimental Approach and Technical Challenges for Studying AmyloidâÇôMembrane Interactions

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