Lipoprotein Analysis A Practical Approach

by Converse, Carolyn A.; Skinner, E. Roy

• ISBN13: 9780199632312
• ISBN10: 0199632316
• Format: Paperback
• Copyright: 1992-08-06
• Publisher: IRL Press

Summary

Lipoproteins play an important role in maintaining the normal distribution of lipids in the body and in the transport of lipophilic substances. They are also implicated, however, in some of the major diseases of the Western world including heart disease and stroke and consequently there hasbeen a dramatic proliferation of research in this area. The focus of this volume is on the methodology of lipoprotein research. It contains a selection of chapters which provide detailed protocols for preparing and separating different lipoproteins, followed by methods for studying their metabolism, presence in different tissues, and interactions withreceptors. Lipoprotein Analysis: A Practical Approach is an essential manual for all biomedical scientists studying these compounds including those interested in their role in diseases of the circulatory system.

Table of Contents

Lipoprotein Separation and Analysis for Clinical Studies

Qualitative and Quantitative Separation of Human Apolipoproteins

Immunological Methods for Studying and Quantifying Lipoproteins and Apolipoproteins

The Separation and Analysis of High-density Lipoprotein (HDL) and Low-density Lipoprotein (LDL) Subfractions

Lipoprotein Turnover and Metabolism

Lipoprotein-receptor Interactions

Methods for the Assay of Enzymes Relevant to Lipoprotein Metabolism Converse

Assay of Lipoprotein Lipase and Hepatic Lipase

Cholesterol Esterifying Enzymes - Lecithin: Cholesterol Acyltransferase (LCAT) and Acylcoenzyme A: Cholesterol Acyltransferase (ACAT)

Assay of 3-hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) Reductase

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