Lipoproteins in Diabetes Mellitus

by Jenkins, Alicia J.

ISBN13:
9781607610236
ISBN10:
160761023X
Edition: 1st
Format: Hardcover
Copyright: 2010-06-15
Publisher: Springer Verlag
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Lipoproteins in Diabetes Mellitus > ISBN13: 9781607610236

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Summary

The book will be arranged into two sections; Basic Science and Clinical Science, to enable the scientist and the more clinically focused reader to readily access the required information. Topics covered will include lipoprotein structure, function and metabolism, with particular emphasis on diabetes-related changes, lipoprotein related research techniques, clinically available research tools, recent major diabetes and lipid related clinical trials, effects of lifestyle and glycemic control on lipoproteins, and the use of the major lipid modifying medications.

OverviewBasic Science
Lipoprotein structure and function
Lipoprotein metabolism including changes in diabetesLipoprotein classes
triglyceride rich lipoproteins (including chylomicrons, vldl and their remnants)
LDL
Lipoprotein (a)
HDLLipoprotein related genes, enzymes and receptors
lipoprotein related genes
Lipoprotein related enzymes 1 (Endothelial based lipases)
Lipoprotein related enzymes 2 (LCAT and CETP, PON and PAFAH))
lipoprotein receptors
Lipoprotein vascular wall interactions
PPAR system in diabeteslipoprotein modifications
lipoprotein glycation
lipoprotein oxidation lipoproteins and immune complexeslipoprotein related research tools
lipoprotein kinetics
lipoprotein subclassing
lipoproteins and cellular interactions
Animal models of diabetic dyslipoproteinemia Clinical Science
the clinical measurement of lipoproteinslipoproteins and vascular damage in diabetes
lipoproteins and endothelial dysfunction
lipoproteins and cardiovascular disease
Lipoproteins and diabetic nephropathy
lipoproteins and diabetic retinopathy
recommended treatment targets and aids to their achievement lipoprotein related trials in diabetes
lipoprotein related trials in diabetes overview (including macro- and microvascular trials)specific major trials in diabetes or with major diabetes sub-studies
Heart proectection study
cards (statin related)
VA-HIT study (Gemfibrozil related)
FIELD study (Fenofibrate related) treatments of lipoprotein disorders in diabetes
effects of lifestyle and glycemic control on lipoproteins in diabetes
effects of drugs on lipoproteins in diabetes
HMG CoA Reductase Inhibitors
Fibric acid derivatives
cholesterol absorption inhbitiors including resins and ezetemibe
other drugs / treatments in developmentincluding ldl apharesis, cetp inhibitors and hdl mimetics
combination drug therapies in diabetes
Future directions
Table of Contents provided by Publisher. All Rights Reserved.

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