Liver Transplantation Clinical Assessment and Management

by Neuberger, James; Ferguson, James; Newsome, Philip N.

• ISBN13: 9781118675915
• ISBN10: 1118675916
• Edition: 1st
• Format: eBook
• Copyright: 2013-10-02
• Publisher: Wiley-Blackwell

Summary

With the number of patients requiring liver transplants on the rise, this practical volume provides much needed answers to critical questions. It explains when to refer a patient for liver transplantation, how to assess a potential liver transplant recipient, how to manage the hospitalized transplant patient, and potential complications. Packed with text features such as key points and "what to avoid" boxes, the text progresses chronologically through each stage of the liver transplantation process. It includes 30 high definition videos of transplant surgery by the world's leading experts, all linked directly to the text.

Table of Contents

List of Contributors, ix

Foreword, xii

Preface, xiv

Acknowledgements, xv

About the Companion Website, xvi

Abbreviations, xvii

PART 1 When to Refer a Patient for Liver Transplantation

1 General Considerations, 3
S. Tamir Rashid and Alexander E. Gimson

2 Prognostic Models in Liver Transplantation, 18
James Neuberger

PART 2 Selection, Assessment and Management on the List

3 Assessing the Potential Transplant Recipient, 29
Diarmaid D. Houlihan and Philip N. Newsome

4 Consent, 39
Christopher J.E. Watson

5 Management on the Waiting List, 47
Sumeet K. Asrani and Jayant A. Talwalkar

6 Specific Diseases, 60
Ian A. Rowe and David J. Mutimer

7 Specific Issues of Selection including Non-Compliance, Futility, Nutritional and Social Issues, 73
Ken Simpson

PART 3 Transplantation for Acute Liver Failure

8 Assessment of the Patient with Acute Liver Failure, 85
Ashley Barnabas and John O’Grady

9 Management of the Patient with Fulminant Hepatic Failure Awaiting Liver Transplantation, 93
James Neuberger

PART 4 Donation and Allocation

10 Liver Donation, 103
Gabriel C. Oniscu

11 Liver Allocation, 116
Richard B. Freeman, Jr

12 Alternatives to Orthotopic Liver Replacement, 125
James Neuberger

13 Surgical Aspects of Liver Transplantation, 129
Thamara Perera and Simon Bramhall

PART 5 Care of the Liver Transplant Recipient

14 Introduction to Outcomes and Follow-Up, 147
James Neuberger

15 The Immune System in Liver Transplantation: Rejection vs.Tolerance, 160
Palak J. Trivedi and Nick D. Jones

16 Immunosuppression in Liver Transplantation, 184
Aaron James Chan and John R. Lake

17 Microbiological Prophylaxis in Liver Transplantation, 197
Matthew J. Armstrong and Philip N. Newsome

18 Managing the Liver Transplant Recipient with Abnormal Liver Blood Tests, 208
Joanna A. Leithead and James Ferguson

19 Managing Rejection, 227
Palak J. Trivedi and James Neuberger

20 Management of Renal Function, 248
James Ferguson

21 Management of Post-Transplant Ascites, 256
Chris Corbett and Philip N. Newsome

22 Cytomegalovirus and the Liver Transplant Recipient, 261
James Ferguson

23 Immunisation and Liver Transplantation, 268
James Neuberger

24 Contraception and Pregnancy, 274
Carlo B. Ramirez, Cataldo Doria, Michael J. Moritz, John M. Davison and
Vincent T. Armenti

25 Common Drug Interactions, 283
Amanda Smith

26 Management of Recurrent Disease, 290
Michael R. Lucey

27 Managing Cardiovascular Risk in the Liver Transplant Recipient, 299
Joanna K. Dowman and Philip N. Newsome

28 Bone Disease in Liver Transplantation, 309
John Ayuk

29 Malignancy after Liver Transplantation, 316
James Neuberger

30 Post-Transplant Lymphoproliferative Disorder, 325
Joseph F. Buell, Nathan J. Shores, Thomas G. Gross, Jeremy R. Chapman and Angela C. Webster

Colour plate section facing p. 170

Index, 337