Lung Cancer Principles and Practice

by Pass, Harvey I.; Carbone, David P.; Johnson, David H.; Minna, John D.; Turrisi, Andrew T.

• ISBN13: 9780781746205
• ISBN10: 0781746205
• Edition: 3rd
• Format: Hardcover
• Copyright: 2004-12-09
• Publisher: LWW

Summary

Thoroughly revised and updated, this Third Edition is the most comprehensive, current reference on lung cancer, with contributions from the world's foremost surgeons, radiation oncologists, medical oncologists, pulmonologists, and basic scientists. This edition includes sixteen new chapters and has been reorganized for greater clinical emphasis. Coverage includes complete information on combined modality treatments for small cell and non-small cell lung cancer and on complications of treatment and management of metastases. Emphasis is also given to early detection, screening, prevention, and new imaging techniques. A new editor, David Carbone, provides state-of-the-art coverage of the molecular genetics and biology of lung cancer.

Table of Contents

Contributors	xi
Preface	xvii
PART I: ETIOLOGY AND EPIDEMIOLOGY	1	(74)
The Etiology and Epidemiology of Lung Cancer	3	(22)
David Schottenfeld
John G. Searle
Role of Cigarette Radicals in Damage to DNA and Other Biomolecules	25	(7)
Koni Stone
William A. Pryor
The Biology of Nicotine Addiction	32	(8)
Neal L. Benowitz
Treatment of Tobacco Dependence	40	(10)
Karl Fagerstrom
Freddi Lewin
Genetic Susceptibility to Lung Cancer	50	(11)
Ann G. Schwartz
Non-Tobacco-Related Lung Carcinogenesis	61	(14)
Tze-Ming Benson Chen
Ware G. Kuschner
PART II: LUNG CANCER BIOLOGY	75	(112)
Genomic Alterations in Lung Cancer	77	(20)
Pierre P. Massion
Epigenetic Changes in Lung Cancer: Pathobiological and Clinical Aspects	97	(21)
Fred R. Hirsch
Adi F. Gazdar
Chromosome 3 Abnormalities in Lung Cancer	118	(17)
Eugene R. Zabarovsky
Michael I. Lerman
John D. Minna
Cell Cycle Gene Alterations in Lung Cancer	135	(12)
Fulvio Lonardo
Sarah Dean
Receptor Tyrosine Kinase Abnormalities in Lung Cancer	147	(13)
Enriqueta Felip
Jose Baselga
Telomerase and Lung Cancer	160	(12)
Jerry W. Shay
Keiko Hiyama
Eiso Hiyama
Clinical and Biologic Implications of EFGR Mutations in Lung Cancer	172	(6)
Jonathan Dowell
Adi F. Gazdar
Hisayuki Shigematsu
Joachim Herz
John D. Mina
Mouse Models of Lung Cancer	178	(9)
Ambra Pozzi
PART III: SCREENING/EARLY DETECTION/ PREVENTION	187	(42)
The Early Detection of Lung Cancer Using Bronchoscopy and Cytologic Analysis	189	(11)
York E. Miller
Thomas L. Petty
Stephen Lam
Molecular Techniques for Early Detection of Lung Cancer and for Studying Preneoplasia	200	(10)
Adi F. Gazdar
John D. Minna
CT Screening for Lung Cancer: The Diagnostic-Prognostic or Dual-Gnostic Approach	210	(10)
Claudia I. Henschke
David F. Yankelevitz
Juan P. Wisnivesky
James P. Smith
Daniel Libby
Mark Pasmantier
Chemoprevention of Lung Cancer	220	(9)
Edward S. Kim
Scott M. Lippman
Waun Ki Hong
PART IV: PATHOLOGY AND MOLECULAR CLASSIFICATION	229	(60)
Molecular and Cellular Pathology of Lung Cancer	231	(30)
Wilbur A. Franklin
Tom Chanin
Adriana Gonzalez
Molecular Profiling of Lung Cancer	261	(9)
Edward Gabrielson
Giovanni Parmigiani
Molecular Prognostication of Lung Cancer	270	(11)
David G. Beer
Techniques and Applications of Tissue Microdissection	281	(8)
Virginia A. Espina
Robert F. Bonner
Lance A. Liotta
Michael R. Emmert-Buck
John W. Gillespie
PART V: CLINICAL PRESENTATION, DIAGNOSIS, STAGING, AND PROGNOSIS	289	(138)
Clinical Presentation of Non-Small Cell Carcinoma of the Lung	291	(13)
Antoinette J. Wozniak
Shirish M. Gadgeel
The Clinical Presentation of Small Cell Lung Cancer	304	(11)
Gregory A. Masters
Conventional Imaging of Non-Small Cell Lung Cancer	315	(32)
Leslie E. Quint
Isaac R. Francis
Barry H. Gross
PET in lung cancer	347	(11)
Johan F. Vansteenkiste
Otto S. Hoekstra
Sigrid G. Stroobants
Egbert F. Smit
Pieter E. Postmus
Tissue Procurement: Bronchoscopic Techniques	358	(14)
Nicholas J. Pastis Jr.
Gerard A. Silvestri
Lung Cancer Staging in Non-Small Cell Lung Cancer Including Preoperative and Intra-Operative Techniques	372	(15)
John R. Roberts
Harvey I. Pass
Staging and Prognostic factors in Small Cell Lung Cancer	387	(13)
Athanassios Argiris
John R. Murren
The Medical Evaluation and Management of the Lung Cancer Patient Pre-Treatment	400	(27)
Jules Lin
Fernando J. Martinez
Mark D. Iannettoni
PART VI: SURGERY	427	(80)
The Non-Small Cell Lung Cancer: Surgery for Early Stage Disease	429	(9)
Jeanne M. Lukanich
David J. Sugarbaker
Adjuvant Chemotherapy in Completely Resected Non-Small Cell Lung Cancer	438	(11)
Giorgio V. Scagliotti
Silvia Novello
Valter Torri
Chest Wall Involvement Including Pancoast Tumors	449	(15)
Craig Hampton
Eric Vallieres
Surgical Management of Second Primary and Metastatic Lung Cancer	464	(11)
Yvonne M. Carter
David M. Jablons
Surgical Management of Small Cell Lung Cancer	475	(16)
Gail E. Darling
Frances A. Shepherd
The Complications of Surgery for Lung Cancer	491	(16)
Michael A. Smith
G. Alexander Patterson
PART VII: RADIATION THERAPY	507	(62)
Radiotherapy for Locally Advanced Lung Cancer	509	(18)
Jeffrey A. Bogart
Andrew T. Turrisi lll
Resectable Non-Small Cell Lung Cancer in the Medically Inoperable Patient	527	(18)
Henry Wagner Jr.
Treatment-Related Lung Damage	545	(24)
Elizabeth L. Travis
Ritsuko Komaki
PART VIII: CHEMOTHERAPY	569	(46)
Chemotherapy for Advanced Non-Small Cell Lung Cancer	571	(17)
Tien Hoang
Anne M. Traynor
Joan H. Schiller
Chemotherapy for Recurrent or Refractory Advanced Non-Small Cell Lung Cancer	588	(12)
Bryan J. Schneider
Gregory P. Kalemkerian
Non-small Cell Lung Cancer in the Elderly: Current Treatment Paradigms	600	(15)
Corey J. Langer
PART IX: MULTIMODALITY THERAPY OF NSCLC	615	(40)
Combined Chemotherapy and Radiotherapy in Locally Advanced, Unresectable Non-Small Cell Lung Cancer	617	(9)
Larry Corum
Janessa Laskin
Andrew T. Turrisi III
David H. Johnson
Preoperative Chemotherapy/Radiation Therapy for Early Stage and Locally Advanced Non-Small Cell Lung Carcinoma	626	(24)
Katherine M. W. Pisters
Nina Mirkovic
Harvey I. Pass
Kathy S. Albain
Postoperative Therapy for Resectable Lung Cancer	650	(5)
Lakshmi Rajdev
Steven M. Keller
PART X: TREATMENT OF SMALL CELL LUNG CANCER	655	(56)
Chemotherapy for Small Cell Lung Cancer	657	(17)
Samir E. Witta
Karen Kelly
Multimodality Therapy for Limited-Stage Small Cell Lung Cancer	674	(18)
Nevin Murray
Sara Erridge
Andrew T. Turrisi III
Treatment of Small Cell Lung Cancer in the Elderly Patient	692	(12)
Frances A. Shepherd
Andrea Bezjak
Prophylactic Cranial Irradiation in Small Cell Lung Cancer	704	(7)
Cecile Le Pechoux
PART XI: NOVEL THERAPEUTIC STRATEGIES	711	(54)
Angiogenesis Therapy in Lung Cancer	713	(12)
Amir Onn
Takeshi Isobe
Roy S. Herbst
Receptor Tyrosine Kinase Inhibitors	725	(9)
Janessa Laskin
David H. Johnson
Gene Therapy	734	(20)
Choon-Taek Lee
David P. Carbone
Immunotherapy	754	(11)
Robert K. Bright
Cynthia A. Jumper
PART XII: PALLIATION AND SPECIAL CONSIDERATIONS	765	(100)
Palliative Chemotherapy	767	(10)
Joanna Hamilton
Mark R. Middleton
Nicholas Thatcher
Penelope Hopwood
Palliative Radiotherapy	777	(17)
Matthew M. Poggi
Francis J. Sullivan
Malignant Pleural and Pericardial Effusions	794	(11)
Shamus R. Carr
Scott W. Cowan
David Zeltsman
Joseph S. Friedberg
Options and Results in Bronchoscopic Interventions	805	(16)
Heinrich D. Becker
Endobronchial and Interstitial Brachyterapy	821	(21)
Burton L. Speiser
The Use of Photodynamic Therapy for Lung Cancer	842	(8)
Harubami Kato
Masahiko Harada
Superior Vena Cava Syndrome: Surgery and Stents	850	(15)
Jonathan C. Nesbitt
PART XIII: OTHER THORACIC TUMORS	865	(44)
Thymoma and Thymic Carcinoma	867	(14)
Daniel A. Vaena
John Henley
Patrick J. Loehrer Sr.
Malignant Mesothelioma	881	(11)
Nicholas J. Vogelzang
Mediastinal Tumors	892	(17)
Mark I. Block
Index	909