Lyme Disease

by Halperin, John J., M.D.

• ISBN13: 9781845938048
• ISBN10: 1845938046
• Edition: 1st
• Format: Hardcover
• Copyright: 2011-10-31
• Publisher: Cab Intl

Summary

Providing the medical practitioner with a broad scientific understanding, this book discusses the causative organism, its requisite ecosystem, disease epidemiology, host-Borrelia interactions, diagnostic testing, clinical manifestations, therapeutic options, and long term prognosis. It explicitly reviews both the basic biology of the infection and practical clinical aspects, linking the two to demonstrate what is and is not attributable to this infection. It is an authoritative guide for medics and researchers involved with diagnosing and treating Lyme, covering biology, epidemiology and therapeutics.

Table of Contents

Contributors	p. vii
Introduction	p. ix
Biological Substrate
Ticks: the Vectors of Lyme Disease	p. 1
Borrelia: Biology of the Organism	p. 29
Botrelia: Interactions with the Host Immune System	p. 54
Laboratory Diagnostic Testing for Botrelia burgdorferi Infection	p. 73
Persistence of Borrelia burgdorferi Infection after Antibiotic Treatment: What Can We Learn from Animal Models?	p. 89
Global Epidemiology of Boirelia burgdorferi Infections	p. 100
Clinical aspects
Antibiotic Therapy for Infection Caused by Botrelia burgdorferi Sensu Lato	p. 115
Lyme Borreliosis in the UK and Ireland	p. 127
Lyme Borreliosis: the European Perspective	p. 140
Erythema Migrans	p. 154
Cardiac Involvement	p. 179
Rheumatological Involvement	p. 190
Nervous System Involvement	p. 208
Lyme Disease in Children	p. 221
The Psychology of 'Post-Lyme Disease Syndrome' and 'Not Lyme'	p. 232
Chronic Lyme Disease	p. 248
Lyme Disease: the Great Controversy	p. 259
Index	p. 271
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