Macrocyclic Lactones in Antiparasitic Therapy

by Vercruysse, J.; Rew, Robert S.

• ISBN13: 9780851996172
• ISBN10: 0851996175
• Format: Hardcover
• Copyright: 2003-02-20
• Publisher: Cab Intl

Summary

Macrocyclic lactones are chemical compounds that represent the main treatment for parasitic diseases of animals, not only for helminth infections, but also a number of major ectoparasitic infestations.There has been no comprehensive book on this subject for more than a decade and this book fills this gap and provides detailed coverage of the basic science of these drugs and their mode of action, as well as their clinical use in farm and companion animals and in humans.

Table of Contents

Contributors	ix
Preface	xiii
Chemistry, Pharmacology and Safety of the Macrocyclic Lactones	1	(96)
Ivermectin, Abamectin and Eprinomectin	1	(29)
W. Shoop
M. Soll
Doramectin and Selamectin	30	(21)
G.A. Conder
W.J. Baker
Milbemycin Oxime	51	(24)
M. Jung
A. Saito
G. Buescher
M. Maurer
J.-F. Graf
Moxidectin	75	(22)
D.W. Rock
R.L. DeLay
M.J. Gliddon
Pharmacokinetics of the Macrocyclic Lactones: Conventional Wisdom and New Paradigms	97	(28)
D.R. Hennessy
M.R. Alvinerie
Mode of Action of the Macrocyclic Lactones	125	(16)
R.J. Martin
A.P. Robertson
A.J. Wolstenholme
Ecological Impact of Macrocyclic Lactones on Dung Fauna	141	(22)
J.W. Steel
K.G. Wardhaugh
Resistance Against Macrocyclic Lactones	163	(20)
R.K. Prichard
The Use of Macrocyclic Lactones to Control Parasites of Cattle	183	(120)
General Efficacy of the Macrocyclic Lactones to Control Parasites of Cattle	185	(38)
J. Vercruysse
R. Rew
Use of Macrocyclic Lactones to Control Cattle Parasites in Europe	223	(25)
J. Vercruysse
R. Rew
Use of Macrocyclic Lactones to Control Cattle Parasites in the USA and Canada	248	(14)
R. Rew
J. Vercruysse
Use of Macrocyclic Lactones to Control Cattle Parasites in South America	262	(26)
C. Eddi
A. Nari
J. Caracostantogolo
Use of Macrocyclic Lactones to Control Cattle Parasites in Australia and New Zealand	288	(15)
P.A. Holdsworth
The Use of Macrocyclic Lactones to Control Parasites of Sheep and Goats	303	(20)
R.L. Coop
I. Barger
F. Jackson
The Use of Macrocyclic Lactones to Control Parasites of Horses	323	(16)
C.M. Monahan
T.R. Klei
The Use of Macrocyclic Lactones to Control Parasites of Pigs	339	(14)
J. Arends
J. Vercruysse
The Use of Macrocyclic Lactones in the Control and Prevention of Heartworm and Other Parasites in Dogs and Cats	353	(18)
J. Guerrero
J.W. McCall
C. Genchi
The Use of Macrocyclic Lactones to Control Parasites of Domesticated Wild Ruminants	371	(24)
S.E. Marley
G.A. Conder
The Use of Macrocyclic Lactones to Control Parasites of Exotic Pets	395	(10)
S.E. Little
C.B. Greenacre
R.M. Kaplan
The Use of Macrocyclic Lactones to Control Parasites of Humans	405	(8)
K.R. Brown
Macrocyclic Lactones as Antiparasitic Agents in the Future	413	(12)
T.G. Geary
Index	425