Macromolecular Symposia 172 : Polymers in Medicine

by Symposium Editor: Jaroslav Kahovec; Editor: I. Meisel; Associate Editor: C. S. Kniep; Associate Editor: S. Spiegel; Assistant Editor: K. Grieve

• ISBN13: 9783527303342
• ISBN10: 3527303340
• Format: Hardcover
• Copyright: 2002-01-01
• Publisher: Wiley-VCH

Summary

Polymers are gaining ever-growing importance in medical research and development, both for their material properties and as conjugates. Although the development of novel materials and applications continues, the focus of research has shifted to the mechanisms of action and interaction of the new materials. This recent understanding has enabled scientists to design and tailor the properties of their products for increasingly specific purposes. 'Polymers in Medicine' was the title of the 40th Microsymposium of the Prague Meetings on Macromolecules. It brought together experts from academia and industry to discuss the application of polymers to biomedical science. This volume of Macromolecular Symposia presents many of the lectures from the meeting and offers an excellent overview of current research in this field.

Table of Contents

Preface (K. Ulbrich and J. Kahovec).

Polyion Complex Micelles with Core-Shell Structure: Their Physiochemical Properties and Utilities as Functional Materials (A. Harada and K. Kataoka).

Crosslinking of Porcine Aortic Leaflets with Butane-1,4-diol Diglycidyl Ether (P. Dijkstra, et al.).

Immunprotective Therapy with Targeted Anticancer Drugs (B. Řfhovaß, et al.).

The Lysosome/Endosome Membrane: A Barrier to Polymer-Based Drug Delivery (J. Lloyd).

Mechanisms of Anticancer Action of HPMA Copolymer Bound Doxorubicin (T. Minko, et al.).

PH-Sensitive Hemolysis by Random Copolymers of Alkyl Acrylates and Acrylic Acid (N. Murthy, et al.).

Amphiphilic Membranes with Controlled Mesh Dimensions for Insulin Delivery (J. Kennedy, et al.).

Protein Release from Poly(ortho ester) Extruded Rods (A. Rothen-Weinhold, et al.).

Treatment of Intralocular Diseases with Poly(ortho ester)-Based Drug Delivery Systems (S. Einmahl, et al.).

Tailot-Made Biomimetic Random Copolymers for Medical Applications (C. Gervelas, et al.).

Immobilization of Concanavalin A to Glucose-Containing Polymers (J. Ju Kim and K. Park).

Selective Energy Depletion and Sensitization of Multiple Drug-Resistant Cancer Cells by Pluronic Block Copolymer (A. Kabanov, et al.).

Biodegradable Graft Polyesters Based on Copolymer of Latice Acid and Glycolic Acids Grafted onto Poly(vinyl alcohol) for Oral Vaccine Delivery (T. Kissel, et al.).

Polymeric Organoiron Compounds as Prodrugs in Cancer Research (E. Neuse).

Physiological Considerations in Dosage Form Design (P. Yeh and P. Smith).

Sulfonamide-Containing Polymers: A New Class of pH-Sensitive Polymers and Gels (S. Kang, et al.).

Hydrogels for Encapsulation of Mammalin Cells (J. Lukßš, et al.).