Management of High-Risk Pregnancy

Covering the most important issues confronting the health professional caring for patients with high-risk pregnancies, this practical tool guides the clinician in the diagnosis and therapy for various complications. The protocols in this book are straightforward, practical and cost-effective, and any unnecessary tests or procedures have been eliminated.

Contributors

viii

Foreword

xiv

Preface

xv

Acknowledgments

xvi

Introduction

xvii

PART I. Factors of High-Risk Pregnancy

Maternal Nutrition

3

(17)

Edward R. Newton

Risks of Alcohol Consumption

20

(6)

Robert A. Welch

Robert J. Sokol

Substance Abuse in Pregnancy

26

(7)

Ruth Anne Queenan

Environmental Agents and Reproductive Risk

33

(10)

Anthony R. Scialli

Armand Lione

Medications in Pregnancy and Lactation

43

(12)

Jennifer R. Niebyl

Neil K. Kochenour

PART II. Procedures

Genetic Amniocentesis and Chorionic Villus Sampling

55

(10)

Sherman Elias

Joe Leigh Simpson

Direct Fetal Blood Sampling: Cordocentesis

65

(9)

John W. Seeds

Ultrasound Diagnosis of Structural Abnormalities

74

(17)

Mary E. D'Alton

Amnioinfusion: Indications and Controversies

91

(10)

Catherine Y. Spong

PART III. Genetics

Genetic Screening for Mendelian Disorders

101

(7)

Carole M. Meyers

Sherman Elias

Screening for Neural Tube Defects

108

(11)

Gary S. Eglinton

Frank D. Seydel

Screening for Aneuploidy

119

(5)

Mark I. Evans

Joseph E. O'Brien

Elena Dvorin

Gregory Critchfield

Antenatal Diagnosis of Inborn Errors of Metabolism

124

(12)

William L. Nyhan

Antenatal Diagnosis by DNA Analysis

136

(11)

Jane Chueh

Mitchell S. Golbus

PART IV. Monitoring: Biochemical and Biophysical

Biochemical Profile of the Fetus

147

(8)

Houchang D. Modanlou

Fetal Lung Maturity

155

(3)

Steven G. Gabbe

Antepartum Fetal Monitoring

158

(9)

Catherine Y. Spong

Interpreting Fetal Heart Tracings

167

(28)

Thomas J. Garite

Richard A. Pircon

PART V. Maternal Disease

Sickle Cell Anemia

195

(5)

Edgar O. Horger III

John V. Dacus

Thromobocytopenia

200

(4)

Ruth Anne Queenan

Cardiovascular Disease

204

(32)

Charles S. Kleinman

Renal Disease

236

(10)

Marshall D. Lindheimer

Adrian I. Katz

The Renal Transplant Recipient

246

(15)

Joseph V. Collea

Mohammad R. Alijani

Irwin R. Merkatz

Gestational Diabetes

261

(5)

Donald R. Coustan

Diabetes Mellitus

266

(5)

Steven G. Gabbe

Hypothyroidism and Hyperthyroidism

271

(3)

Jorge H. Mestman

Asthma

274

(9)

J. Patrick Lavery

Epilepsy

283

(5)

Neil K. Kochenour

Chronic Hypertension

288

(5)

Frederick P. Zuspan

Systemic Lupus Erythematosus

293

(4)

Robert Resnik

Toxoplasmosis

297

(7)

Antonio V. Sison

John L. Sever

Rubella

304

(6)

John H. Grossman III

Cytomegalovirus Infections

310

(8)

Antonio V. Sison

John L. Sever

Varicella-Zoster Virus Infection

318

(5)

James A. McGregor

Nancy Madinger

Herpes Simplex Infection

323

(3)

Marvin S. Amstey

Group B Steptococcus Infection

326

(7)

Mara J. Dinsmoor

Hepatitis in Pregnancy

333

(5)

Carol A. Stamm

James A. McGregor

Parvovirus B19 Infection

338

(5)

Philip B. Mead

HIV Infection

343

(8)

Howard L. Minkoff

Traci Burgess

PART VI. Pregnancy Complications

Genetic Causes of Spontaneous Abortion

351

(6)

Joe Leigh Simpson

Nongenetic Causes of Recurrent Fetal Loss

357

(6)

Sandra Ann Carson

The Incompetent Cervix

363

(5)

Helain J. Landy

Preeclampsia-Eclampsia

368

(9)

Dorel Abramovici

Baha M. Sibai

Emergency Care in Pregnancy

377

(10)

Robert H. Hayashi

Intrauterine Growth Restriction

387

(12)

John T. Queenan

Rh and Other Blood Group Immunizations

399

(14)

John T. Queenan

Multiple Pregnancy

413

(10)

John Patrick O'Grady

Polyhydramnios and Oligohydramnios

423

(10)

John T. Queenan

Prevention of Prematurity in Women with No History of Preterm Birth

433

(17)

Alessandro Ghidini

Prenatal Care for Women with a History of Preterm Birth

450

(9)

Jay D. Iams

Preterm Premature Rupture of Membranes: Infection and Inflammation

459

(7)

James A. McGregor

Placenta Previa and Related Disorders

466

(11)

Charles J. Lockwood

Edmund F. Funai

PART VII. Complications of Labor and Delivery

Prolonged Pregnancy

477

(13)

Jeffrey C. King

Cesarean Section

490

(5)

Edward J. Quilligan

Breech Delivery

495

(6)

Martin L. Gimovsky

Roy H. Petrie

Epidural Anesthesia

501

(6)

Young K. Shin

PART VIII. Neonatal Considerations

Assessing Maturity

507

(6)

Larry N. Cook

Thermoregulation

513

(8)

K. N. Sivasubramanian

Perinatal Asphyxia

521

(4)

Roger K. Freeman

Dawn E. Collins

Neonatal Hypocalcemia

525

(5)

Sergio Demarini

Reginald C. Tsang

Extracorporeal Membrane Oxygenation

530

(7)

Martin Keszler

K. N. Sivasubramanian

Human Milk as a Nutritional and Bioactive Substance

537

(6)

Carol L. Wagner

Index

543

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