Dr Catherine Spong, Bethesda, USA
Charles Lockwood, Department of Obstretics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, USA
List of contributors | p. vii |
Foreword | p. x |
Preface | p. xi |
Acknowledgments | p. xii |
Factors of High-Risk Pregnancy | |
Overview of high-risk pregnancy | p. 3 |
Maternal nutrition | p. 6 |
Alcohol and substance abuse | p. 24 |
Environmental agents and reproductive risk | p. 31 |
Medications in pregnancy and lactation | p. 38 |
Genetics | |
Genetic screening for mendelian disorders | p. 61 |
Screening for neural tube defects | p. 67 |
First and second trimester screening for fetal aneuploidy | p. 72 |
Monitoring: Biochemical and Biophysical | |
Fetal endocrinology | p. 81 |
Fetal lung maturity | p. 91 |
Antepartum fetal monitoring | p. 95 |
Interpreting intrapartum fetal heart tracings | p. 104 |
Maternal Disease | |
Sickle cell disease | p. 109 |
Thrombocytopenia | p. 113 |
Inherited and acquired thrombophilias | p. 119 |
Pathophysiology and diagnosis of thromboembolic disorders in pregnancy | p. 133 |
Cardiac disease in pregnancy | p. 143 |
Renal disease in pregnancy | p. 163 |
Pregnancy in transplant patients | p. 168 |
Gestational diabetes mellitus | p. 176 |
Diabetes mellitus | p. 182 |
Maternal hypothyroidism and hyperthyroidism | p. 186 |
Asthma | p. 192 |
Epilepsy | p. 201 |
Chronic hypertension | p. 210 |
Systemic lupus erythematosus | p. 214 |
Perinatal infections | p. 222 |
Group B streptococcal infections | p. 234 |
Hepatitis in pregnancy | p. 238 |
HIV infection | p. 242 |
Obstetric Complications | |
Genetic and nongenetic causes of spontaneous abortion | p. 253 |
The incompetent cervix | p. 263 |
Gestational hypertension-preeclampsia and eclampsia | p. 271 |
Emergency care in pregnancy | p. 280 |
Sonographic dating and standard fetal biometry | p. 286 |
Rh and other blood group alloimmunizations | p. 298 |
Multiple pregnancy | p. 304 |
Polyhydramnios and oligohydramnios | p. 316 |
Prevention of preterm birth | p. 326 |
Pathogenesis and prediction of preterm delivery | p. 333 |
Preterm premature rupture of membranes | p. 345 |
Management of preterm labor | p. 354 |
Placenta previa and related placental disorders | p. 362 |
Complications of Labor and Delivery | |
Prolonged pregnancy | p. 373 |
Cesarean delivery | p. 382 |
Vaginal birth after cesarean delivery | p. 389 |
Breech delivery | p. 397 |
Obstetric analgesia and anesthesia | p. 401 |
Procedures | |
Genetic amniocentesis and chorionic villus sampling | p. 409 |
Direct fetal blood sampling: cordocentesis | p. 419 |
Amnioinfusion: indications and controversies | p. 425 |
Fetal surgery | p. 433 |
Problems in the newborn | p. 442 |
Neonatal encephalopathy and cerebral palsy | p. 452 |
Index | p. 459 |
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