Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases

by Mandell, Gerald L.; Bennett, John E.; Dolin, Raphael

• ISBN13: 9780443075933
• ISBN10: 044307593X
• Edition: 5th
• Format: Hardcover
• Copyright: 1999-11-01
• Publisher: Elsevier Science Health Science div

Summary

Widely acknowledged as the most definitive reference source of its kind, here is the 5th Edition of this acclaimed text. Authored by a "who's who" of experts from around the world, this lavishly illustrated 2-volume set covers microbiology, immunology, and treatment of infectious agents. With a completely updated bank of references, it is a complete, essential compendium of knowledge on this vast and complex subject.

Table of Contents

VOLUME 1
PART I Basic Principles in the Diagnosis and Management of Infectious Diseases	1	(1)
SECTION A. MICROBIAL VIRULENCE FACTORS	2	(29)
A Molecular Perspective of Microbial Pathogenicity	2	(11)
David A. Relman
Stanley Falkow
Microbial Adherence	13	(8)
William A. Petri, Jr.
Barbara J. Mann
Toxins	21	(10)
Erik L. Hewlett
SECTION B. HOST DEFENSE MECHANISMS	31	(125)
Innate (General or Nonspecific) Host Defense Mechanisms	31	(8)
Edmund C. Tramont
David L. Hoover
Human Genetics and Infection	39	(6)
Adrian V. S. Hill
Antibodies	45	(22)
Frederick P. Heinzel
Complement	67	(22)
Peter Densen
Granulocytic Phagocytes	89	(23)
William M. Nauseef
Robert A. Clark
Cell-Mediated Immunity in Host Defense against Infectious Diseases	112	(34)
Raymond M. Johnson
Eric J. Brown
Evaluation of the Patient with Suspected Immunodeficiency	146	(10)
Steven M. Holland
John I. Gallin
SECTION C. EPIDEMIOLOGY OF INFECTIOUS DISEASES	156	(28)
Epidemiologic Principles	156	(11)
Michael T. Osterholm
Craig W. Hedberg
Kristine A. Moore
Global Epidemiology of Infectious Diseases	167	(11)
Stephen M. Ostroff
James W. Leduc
New and Emerging Infections Diseases	178	(6)
Joseph E. McDade
James M. Hughes
SECTION D.	184	(39)
The Clinician and the Microbiology Laboratory	184	(39)
Vee J. Gill
Daniel P. Fedorko
Frank G. Witebsky
SECTION E. ANTI-INFECTIVE THERAPY	223	(380)
Principles of Anti-infective Therapy	223	(13)
Robert C. Moellering, Jr.
Mechanisms of Bacterial Antibiotic Resistance	236	(17)
Steven M. Opal
Kenneth H. Mayer
Antone A. Medeiros
Pharmacokinetics and Pharmacodynamics of Anti-infective Agents	253	(8)
Guy W. Amsden
Charles H. Ballow
Joseph S. Bertino, Jr.
Penicillins	261	(13)
Henry F. Chambers
Cephalosporins	274	(17)
Adolf W. Karchmer
Other βLactam Antibiotics	291	(8)
Henry F. Chambers
βLactam Allergy	299	(7)
Michael E. Weiss
N. Franklin Adkinson, Jr.
Fusidic Acid	306	(1)
Lionel A. Mandell
Aminoglycosides	307	(29)
David N. Gilbert
Tetracyclines and Chloramphenicol	336	(12)
Harold C. Standiford
Rifamycins	348	(13)
Barry M. Farr
Metronidazole	361	(5)
Sydney M. Finegold
Macrolides and Clindamycin	366	(16)
Neal H. Steigbigel
Vancomycin, Teicoplanin, and the Streptogramins: Quinupristin and Dalfopristin	382	(10)
Robert Fekety
Oxazolidinones	392	(2)
Gerald R. Donowitz
Sulfonamides and Trimethoprim	394	(10)
Stephen H. Zinner
Kenneth H. Mayer
Quinolones	404	(19)
David C. Hooper
Urinary Tract Agents: Nitrofurantoin and Methenamine	423	(5)
David C. Hooper
Topical Antibacterials	428	(8)
Allan R. Tunkel
Antimycobacterial Agents	436	(12)
Richard J. Wallace, Jr.
Antifungal Agents	448	(12)
David A. Stevens
John E. Bennett
Antiviral Drugs (Other Than Antiretrovirals)	460	(31)
Frederick G. Hayden
Immunomodulators	491	(10)
Michael O. Frank
Gerald L. Mandell
Hyperbaric Oxygen	501	(4)
Jean Marie Mulinde
Ellis S. Caplan
Agents Active Against Parasites and Pneumocystis carinii	505	(34)
Richard D. Pearson
Antimicrobial Management and Cost Containment	539	(7)
Neil O. Fishman
Outpatient Intravenous Antibiotic Therapy	546	(5)
Alan D. Tice
Tables of Antimicrobial Agent Pharmacology	551	(52)
Guy W. Amsden
PART II Major Clinical Syndromes	603	(1)
SECTION A. Fever	604	(47)
Temperature Regulation and the Pathogenesis of Fever	604	(18)
Philip A. Mackowiak
Fever of Unknown Origin	622	(11)
Philip A. Mackowiak
David T. Durack
The Acutely III Patient with Fever and Rash	633	(18)
David J. Weber
Myron S. Cohen
Jo-David Fine
SECTION B. UPPER RESPIRATORY TRACT INFECTIONS	651	(52)
The Common Cold	651	(5)
Jack M. Gwaltney, Jr.
Pharyngitis	656	(6)
Jack M. Gwaltney, Jr.
Alan L. Bisno
Acute Laryngitis	662	(1)
Mary T. Caserta
Acute Laryngotracheobronchitis (Croup)	663	(6)
Caroline Breese Hall
John T. McBride
Otitis Externa, Otitis Media, and Mastoiditis	669	(7)
Jerome O. Klein
Sinusitis	676	(10)
Jack M. Gwaltney, Jr.
Epiglottitis	686	(3)
James E. Burns
J. Owen Hendley
Infections of the Oral Cavity, Neck, and Head	689	(14)
Anthony W. Chow
SECTION C. PLEUROPULMONARY AND BRONCHIAL INFECTIONS	703	(70)
Acute Bronchitis	703	(3)
Jack M. Gwaltney, Jr.
Chronic Bronchitis and Acute Infectious Exacerbations	706	(4)
Herbert Y. Reynolds
Bronchiolitis	710	(7)
Caroline Breese Hall
John T. McBride
Acute Pneumonia	717	(26)
Gerald R. Donowitz
Gerald L. Mandell
Pleural Effusion and Empyema	743	(8)
Richard E. Bryant
Christopher J. Salmon
Lung Abscess	751	(4)
Sydney M. Finegold
Chronic Pneumonia	755	(12)
William E. Dismukes
Cystic Fibrosis	767	(6)
M. R. Knowles
P. H. Gilligan
R. C. Boucher
SECTION D.	773	(33)
Urinary Tract Infections	773	(33)
Jack D. Sobel
Donald Kaye
SECTION E.	806	(15)
Sepsis Syndrome	806	(15)
Lowell S. Young
SECTION F.	821	(36)
Peritonitis and Other Intra-abdominal Infections	821	(36)
Matthew E. Levison
Larry M. Bush
SECTION G. CARDIOVASCULAR INFECTIONS	857	(93)
Endocarditis and Intravascular Infections	857	(46)
Arnold S. Bayer
W. Michael Scheld
Infections of Prosthetic Valves and Intravascular Devices	903	(14)
Adolf W. Karchmer
Prophylaxis of Infective Endocarditis	917	(8)
David T. Durack
Myocarditis and Pericarditis	925	(16)
Maria C. Savoia
Michael N. Oxman
Mediastinits	941	(9)
Mark E. Rupp
SECTION H. CENTRAL NERVOUS SYSTEM INFECTIONS	950	(87)
Approach to the Patient with Central Nervous System Infections	950	(9)
Thomas P. Bleck
John E. Greenlee
Acute Meningitis	959	(38)
Allan R. Tunkel
W. Michael Scheld
Chronic Meningitis	997	(12)
Barbara M. Gripshover
Jerrold J. Ellner
Encephalitis, Myelitis, and Neuritis	1009	(7)
Diane E. Griffin
Brain Abscess	1016	(12)
Allan R. Tunkel
Brian Wispelwey
W. Michael Scheld
Subdural Empyema	1028	(3)
Thomas P. Bleck
John E. Greenlee
Epidural Abscess	1031	(3)
Thomas P. Bleck
John E. Greenlee
Suppurative Intracranial Phlebitis	1034	(3)
Thomas P. Bleck
John E. Greenlee
SECTION I. SKIN AND SOFT TISSUE INFECTIONS	1037	(39)
Cellulitis and Subcutaneous Tissue Infections	1037	(21)
Morton N. Swartz
Myositis	1058	(8)
Morton N. Swartz
Lymphadenitis and Lymphangitis	1066	(10)
Morton N. Swartz
SECTION J. GASTROINTESTINAL INFECTIONS AND FOOD POISONING	1076	(99)
Principles and Syndromes of Enteric Infection	1076	(18)
Richard L. Guerrant
Theodore S. Steiner
Esophagitis	1094	(4)
Paul S. Graman
Nausea, Vomiting, and Noninflammatory Diarrhea	1098	(13)
Richard L. Guerrant
David A. Bobak
Antibiotic-Associated Colitis	1111	(15)
Nathan M. Thielman
Inflammatory Enteritides	1126	(10)
Richard L. Guerrant
Aldo A. M. Lima
Enteric Fever and Other Causes of Abdominal Symptoms with Fever	1136	(14)
Richard D. Pearson
Richard L. Guerrant
Foodborne Disease	1150	(15)
Robert V. Tauxe
David L. Swerdlow
James M. Hughes
Tropical Sprue/Enteropathy	1165	(5)
Christine A. Wanke
Richard L. Guerrant
Whipple's Disease	1170	(5)
Thomas Marth
SECTION K. BONE AND JOINT INFECTIONS	1175	(26)
Infectious Arthritis	1175	(7)
James W. Smith
M. Shahbaz Hasan
Osteomyelitis	1182	(14)
Jon T. Mader
Jason Calhoun
Infections with Prostheses in Bones and Joints	1196	(5)
Barry D. Brause
SECTION L. DISEASES OF THE REPRODUCTIVE ORGANS AND SEXUALLY TRANSMITTED DISEASES	1201	(50)
Genital Skin and Mucous Membrane Lesions	1201	(7)
Michael F. Rein
Urethritis	1208	(10)
William M. McCormack
Michael F. Rein
Vulvovaginitis and Cervicitis	1218	(17)
Michael F. Rein
Infections of the Female Pelvis	1235	(8)
Philip B. Mead
Prostatitis, Epididymitis, and Orchitis	1243	(8)
John N. Krieger
SECTION M. EYE INFECTIONS	1251	(28)
Conjunctivitis	1251	(6)
Terrence P. O'Brien
Keratitis	1257	(10)
Terrence P. O'Brien
Endophthalmitis	1267	(6)
Terrence P. O'Brien
Periocular Infections	1273	(6)
Terrence P. O'Brien
SECTION N. HEPATITIS	1279	(53)
Acute Viral Hepatitis	1279	(18)
Hiroshi Kawai
Stephen M. Feinstone
Chronic Hepatitis	1297	(35)
Thomas A. Shaw-Stiffel
SECTION O. ACQUIRED IMMUNODEFICIENCY SYNDROME	1332	(197)
Global Perspectives on Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome	1332	(8)
Peter Piot
Michael H. Merson
Epidemiology and Prevention of Acquired Immunodeficiency Syndrome and Human Immunodeficiency Virus Infection	1340	(29)
Carlos Del Rio
James W. Curran
Detection of Human Immunodeficiency Virus Infection	1369	(5)
Lisa M. Demeter
Richard C. Reichman
The Immunology of Human Immunodeficiency Virus Infection	1374	(24)
Oren Cohen
Claudia Cicala
Mauro Vaccarezza
Anthony S. Fauci
General Clinical Manifestations of Human Immunodeficiency Virus Infection (Including Oral, Cutaneous, Renal, Ocular, and Cardiac Diseases)	1398	(17)
Richard E. Chaisson
Timothy R. Sterling
Joel E. Gallant
Pulmonary Manifestations of Human Immunodeficiency Virus Infection	1415	(11)
Judith Falloon
Gastrointestinal and Hepatobiliary Manifestations of Human Immunodeficiency Virus Infection	1426	(6)
Mark S. Sulkowski
Richard E. Chaisson
Neurologic Manifestations of Human Immunodeficiency Virus Infection	1432	(7)
Robert G. Holloway, Jr.
Karl D. Kieburtz
Malignancies in Human Immunodeficiency Virus Infection	1439	(13)
Phoebe R. Trubowitz
Paul A. Volberding
Human Immunodeficiency Virus Infection in Women	1452	(15)
Susan E. Cohn
Rebecca A. Clark
Pediatric Human Immunodeficiency Virus Infection	1467	(12)
Geoffrey A. Weinberg
Antiretroviral Therapy of Human Immunodeficiency Virus Infection	1479	(21)
George J. Hanna
Martin S. Hirsch
Management of Opportunistic Infections Associated with Human Immunodeficiency Virus Infection	1500	(19)
Henry Masur
Vaccines for Human Immunodeficiency Virus-1 Infection	1519	(10)
Raphael Dolin
Michael C. Keefer
SECTION P. MISCELLANEOUS SYNDROMES	1529	(6)
Chronic Fatigue Syndrome	1529	(6)
N. Cary Engleberg
Index i
VOLUME 2
PART III Infectious Diseases and Their Etiologic Agents	1535	(1)
SECTION A. VIRAL DISEASES	1536	(435)
Introduction to Viruses and Viral Diseases	1536	(16)
Terence S. Dermody
Kenneth L. Tyler
DNA Viruses
Paxviridae
Introduction to Poxiviridae	1552	(1)
John M. Neff
Vaccinia Virus (Cowpox)	1553	(2)
John M. Neff
Variola (Smallpox) and Monkeypox Viruses	1555	(1)
John M. Neff
Parapoxviruses, Molluscum Contagiosum, and Tanapox Viruses	1556	(1)
John M. Neff
Herpesviridae
Introduction to Herpesviridae	1557	(7)
Stephen E. Straus
Herpes Simplex Virus	1564	(16)
Lawrence Corey
Varicella-Zoster Virus	1580	(6)
Richard J. Whitley
Cytomegalovirus	1586	(13)
Clyde S. Crumpacker
Epstein-Barr Virus (Infectious Mononucleosis)	1599	(14)
Robert T. Schooley
Human Herpesvirus Types 6 and 7	1613	(5)
Stephen E. Straus
Human Herpesvirus Type 8 (Kaposi's Sarcoma-Associated Herpesvirus)	1618	(3)
Stephen E. Straus
Herpes B Virus	1621	(3)
Stephen E. Straus
Adenoviridae
Adenovirus	1624	(6)
Stephen G. Baum
Papovaviridae
Papillomaviruses	1630	(15)
William Bonnez
Richard C. Reichman
JC, BK, and Other Polymaviruses; Progressive Multifocal Leukoencephalopathy	1645	(7)
Lisa M. Demeter
Hepadnaviridae
Hepatitis B Virus and Hepatitis D Virus	1652	(33)
William S. Robinson
Parvoviridae
Parvovirus B19	1685	(8)
Kevin E. Brown
RNA VIRUSES
Reoviridae
Orthoreoviruses and Orbiviruses	1693	(1)
Theodore F. Tsai
Coltiviruses (Colorado Tick Fever)	1694	(9)
Theodore F. Tsai
Rotavirus	1696
Paul A. Offit
Togaviridae
Alphaviruses	1703	(5)
Lewis Markoff
Rubella Virus (German Measles)	1708	(6)
Anne A. Gershon
Flaviviruses
Flaviviruses (Yellow Fever, Dengue, Dengue Hemorrhagic Fever, Japanese Encephalitis, St. Louis Encephalitis, Tick-Borne Encephalitis)	1714	(22)
Theodore F. Tsai
Hepatitis C	1736	(24)
David L. Thomas
Stanley M. Lemon
Hepatitis G. Virus and TT Virus	1760	(7)
Harvey J. Alter
Coronaviridae
Coronaviruses	1767	(3)
Kenneth Mclntosh
Paramyxoviridae
Parainfluenza Viruses	1770	(6)
Peter F. Wright
Mumps Virus	1776	(6)
Stephen G. Baum
Nathan Litman
Respiratory Syncytial Virus	1782	(19)
Caroline Breese Hall
Carol A. McCarthy
Measles Virus (Rubeola)	1801	(8)
Anne A. Gershon
Rhabdoviridae
Vesicular Stomatitis and Related Viruses	1809	(2)
Steven M. Fine
Rabies Virus	1811	(10)
Thomas P. Bleck
Charles E. Rupprecht
Filoviridae
Marburg and Ebola Virus Hemorrhagic Fevers	1821	(2)
C. J. Peters
Onthomyxoviridae
Influenza Virus	1823	(26)
John J. Treanor
Bunyaviridae
California Encephalitis, Hantavirus Pulmonary Syndrome, and Bunyavirid Hemorrhagic Fevers	1849	(6)
C. J. Peters
Arenaviridae
Lymphocytic Choriomeningitis Virus, Lassa Virus, and the South American Hemorrhagic Fevers	1855	(7)
C. J. Peters
Retroviridae
Human T-cell Lymphotropic Virus Types I and II	1862	(12)
Jainulabdeen J. lfthikharuddin
Joseph D. Rosenblatt
Human Immunodeficiency Viruses	1874	(14)
Howard Z. Streicher
Marvin S. Reitz, Jr.
Robert C. Gallo
Picornaviridae
Introduction to Picornaviridae	1888	(7)
John F. Modlin
Poliovirus	1895	(9)
John F. Modlin
Coxsackieviruses, Echoviruses, and Newer Enteroviruses	1904	(16)
John F. Modlin
Hepatitis A Virus	1920	(20)
Stephen M. Feinstone
lan D. Gust
Rhinovirus	1940	(9)
Jack M. Gwaltney, Jr.
Caliciviridae and Other Gastroenteritis Viruses
Norwalk Virus and Other Caliciviruses	1949	(7)
John J. Treanor
Raphael Dolin
Astroviruses, Toroviruses, and Picobirnaviruses	1956	(2)
John J. Treanor
Raphael Dolin
Unclassified Viruses
Hepatitis E Virus	1958	(13)
Robert H. Purcell
Suzanne U. Emerson
SECTION B. Prion Diseases	1971	(15)
Prions and Prion Diseases of the Central Nervous System (Transmissible Neurodegenerative Diseases)	1971	(15)
Kenneth L. Tyler
SECTION C. Chlamydial Diseases	1986	(29)
Introduction to Chlamydial Diseases	1986	(3)
Robert B. Jones
Byron E. Batteiger
Chlamydia trachomatis (Trachoma, Perinatal Infections, Lymphogranuloma Venereum, and Other Genital Infections)	1989	(15)
Robert B. Jones
Byron E. Batteiger
Chlamydia psittaci (Psittacosis)	2004	(3)
David Schlossberg
Chlamydia pneumoniae	2007	(8)
Lisa A. Jackson
J. Thomas Grayston
SECTION D. Mycoplasma Diseases	2015	(18)
Introduction to Mycoplasma Diseases	2015	(3)
Stephen G. Baum
Mycoplasma pneumoniae and Atypical Pneumonia	2018	(9)
Stephen G. Baum
Ureaplasma urealyticum, Mycoplasma hominis, and Mycoplasma genitalium	2027	(6)
David Taylor-Robinson
SECTION E. Rickettsioses and Ehrlichioses	2033	(32)
Introduction to Rickettsioses and Ehrlichioses	2033	(2)
Alfred J. Saah
Rickettsia rickettsii and Other Spotted Fever Group Rickettsiae (Rocky Mountain Spotted Fever and Other Spotted Fevers)	2035	(7)
David H. Walker
Didier Raoult
Rickettsia akari (Rickettsialpox)	2042	(1)
Alfred J. Saah
Coxiella burnetii (Q Fever)	2043	(7)
Thomas J. Marrie
Rickettsia prowazekii (Epidemic or Louse-Borne Typhus)	2050	(3)
Alfred J. Saah
Rickettsia typhi (Murine Typhus)	2053	(3)
J. Stephen Dumler
David H. Walker
Orientia tsutsugamushi (Scrub Typhus)	2056	(1)
Alfred J. Saah
Ehrlichia chaffeensis (Human Monocytotropic Ehrlichiosis), Ehrlichia phagocytophila (Human Granulocytotropic Ehrlichiosis), and Other Ehrlichiae	2057	(8)
David H. Walker
J. Stephen Dumler
SECTION F. Bacterial Diseases	2065	(590)
Introduction to Bacterial Diseases	2065	(4)
Howard S. Gold
Barry I. Eisenstein
Gram-Positive COCCI
Staphylococcus aureus (Including Staphylococcal Toxic Shock)	2069	(23)
Francis A. Waldvogel
Staphylococcus epidermidis and other Coagulase-Negative Staphylococci	2092	(8)
Gordon L. Archer
Classification of Streptococci	2100	(1)
Alan L. Bisno
Ivo van de Rijn
Streptococcus pyogenes (Including Streptococcal Toxic Shock Syndrome and Necrotizing Fasciitis)	2101	(16)
Alan L. Bisno
Dennis L. Stevens
Nonsuppurative Poststreptococcal Sequelae: Rheumatic Fever and Glomerulonephritis	2117	(11)
Alan L. Bisno
Streptococcus pneumoniae	2128	(19)
Daniel M. Musher
Enterococcus Species, Streptococcus bovis, and Leuconostoc Species	2147	(9)
Robert C. Moellering, Jr.
Streptococcus agalactiae (Group B Streptococcus)	2156	(11)
Morven S. Edwards
Carol J. Baker
Viridans Streptococci and Groups C and G Streptococci	2167	(16)
Caroline C. Johnson
Allan R. Tunkel
Streptococcus intermedius Group	2183	(7)
Suresh J. Antony
Charles W. Stratton
Gram-Positive Bacilli
Corynebacterium diphtheriae	2190	(8)
Rob Roy MacGregor
Other Corynebacteria and Rhodococcus	2198	(10)
Arthur E. Brown
Listeria monocytogenes	2208	(7)
Bennett Lorber
Bacillus anthracis (Anthrax)	2215	(5)
Daniel P. Lew
Other Bacillus Species	2220	(6)
Carmelita U. Tuazon
Erysipelothrix rhusiopathiae	2226	(2)
Annette C. Reboli
W. Edmund Farrar
Gram-Negative Cocci
Neisseria meningitidis	2228	(14)
Michael A. Apicella
Neisseria gonorrhoeae	2242	(17)
P. Frederick Sparling
H. Hunter Handsfield
Moraxella (Branhamella) catarrhalis and Other Gram-Negative Cocci	2259	(13)
Timothy f. Murphy
Gram-Negative Bacilli
Vibrio cholerae	2266
Carlos Seas
Other Pathogenic Vibrios	2272	(4)
Marguerite A. Neill
Charles C. J. Carpenter
Campylobacter jejuni and Related Species	2276	(9)
Martin J. Blaser
Helicobacter pylori and Related Organisms	2285	(9)
Martin J. Blaser
Enterobacteriaceae	2294	(16)
Barry I. Eisenstein
Dori F. Zaleznik
Pseudomonas aeruginosa	2310	(25)
Matthew Pollack
Stenotrophomonas maltophilia and Burkholderia cepacia	2335	(4)
Shahe Vartivarian
Elias Anaissie
Acinetobacter Species	2339	(5)
David M. Allen
Barry J. Hartman
Salmonella Species, Including Salmonella typhi	2344	(19)
Samuel I. Miller
David A. Pegues
Shigella Species (Bacillary Dysentery)	2363	(6)
Herbert L. DuPont
Haemophilus influenzae	2369	(9)
E. Richard Moxon
Timothy F. Murphy
Haemophilus Species (Including Chancroid)	2378	(5)
W. Lee Hand
Gardnerella vaginalis and Mobiluncus Species	2383	(3)
Carol A. Spiegel
Brucella Species	2386	(7)
Edward J. Young
Francisella tularensis (Tularemia)	2393	(9)
J. Thomas Cross Jr.
Robert L. Penn
Pasteurella Species	2402	(4)
John J. Zurlo
Yersinia Species, Including Plague	2406	(8)
Thomas Butler
Bordetella Species	2414	(8)
Erik L. Hewlett
Streptobacillus moniliformis (Rat-Bite Fever)	2422	(2)
Ronald G. Washburn
Legionella pneumophila (Legionnaires' Disease)	2424	(11)
Victor L. Yu
Other Legionella Species	2435	(6)
Robert R. Muder
Capnocytophaga	2441	(3)
Vee J. Gill
Bartonella Species, Including Cat-Scratch Disease	2444	(13)
Leonard N. Slater
David F. Welch
Calymmatobacterium granulomatis (Donovanosis, Granuloma Inguinale)	2457	(2)
Ronald C. Ballard
Other Gram-negative Bacilli	2459	(15)
James P. Steinberg
Carlos Del Rio
Spirochetes
Treponema pallidum (Syphilis)	2474	(16)
Edmund C. Tramont
Treponema Species (Yaws, Pinta, Bejel)	2490	(5)
Jeffrey D. Chulay
Leptospira Species (Leptospirosis)	2495	(7)
Jordan W. Tappero
David A. Ashford
Bradley A. Perkins
Borrelia Species (Relapsing Fever)	2502	(2)
Warren D. Johnson Jr.
Linnie M. Golightly
Borrelia burgdorferi (Lyme Disease, Lyme Borreliosis)	2504	(14)
Allen C. Steere
Spirillum minus (Rat-Bite Fever)	2518	(1)
Ronald G. Washburn
Anaerobic Bacteria
Anaerobic Bacteria: General Concepts	2519	(18)
Sydney M. Finegold
Clostridium tetani (Tetanus)	2537	(6)
Thomas P. Bleck
Clostridium botulinum (Botulism)	2543	(6)
Thomas P. Bleck
Gas Gangrene and Other Clostridium-Associated Diseases	2549	(12)
Bennett Lorber
Bacteroides, Prevotella, Porphyromonas, and Fusobacterium Species (and Other Medically Important Anaerobic Gram-Negative Bacilli)	2561	(9)
Bennett Lorber
Anaerobic Cocci	2570	(3)
Ellen M. Mascini
Jan Verhoef
Anaerobic Gram-Positive Nonsporulating Bacilli	2573	(3)
Ellen M. Mascini
Jan Verhoef
Mycobacterial Diseases
Mycobacterium tuberculosis	2576	(32)
David W. Haas
Mycobacterium leprae (Leprosy, Hansen's Disease)	2608	(8)
Robert H. Gelber
Thomas H. Rea
Mycobacterium avium Complex	2616	(14)
Diane V. Havlir
Jerrold J. Ellner
Infections Due to Nontuberculous Mycobacteria	2630	(7)
Barbara A. Brown
Richard J. Wallace, Jr.
Higher Bacterial Diseases
Nocardia Species	2637	(8)
Tania C. Sorrell
Jonathan R. Iredell
David H. Mitchell
Agents of Actinomycosis	2645	(10)
Thomas A. Russo
SECTION G. Mycoses	2655	(141)
Introduction to Mycoses	2655	(1)
John E. Bennett
Candida Species	2656	(18)
John E. Edwards, Jr.
Aspergillus Species	2674	(11)
David W. Denning
Agents of Mucormycosis and Related Species	2685	(10)
Alan M. Sugar
Sporothrix schenckii	2695	(4)
John H. Rex
Pablo C. Okhusen
Agents of Chromomycosis	2699	(3)
Kenneth F. Wagner
Agents of Mycetoma	2702	(5)
El Sheikh Mahgoub
Cryptococcus neoformans	2707	(11)
Richard D. Diamond
Histoplasma capsulatum	2718	(15)
George S. Deepe, Jr.
Blastomyces dermatitidis	2733	(13)
Stanley W. Chapman
Coccidioides immitis	2746	(11)
John Galgiani
Dermatophytosis and Other Superficial Mycoses	2757	(11)
Roderick J. Hay
Paracoccidioides brasiliensis	2768	(4)
Angela Restrepo
Miscellaneous Fungi and Prototheca	2772	(9)
Duane R. Hospenthal
John E. Bennett
Pneumocystis carinii	2781	(15)
Peter D. Walzer
SECTION H. Protozoal Diseases	2796	(138)
Introduction to Protozoal Diseases	2796	(2)
Jonathan I. Ravdin
Entamoeba histolytica (Amebiasis)	2798	(13)
Jonathan I. Ravdin
Free-Living Amebas	2811	(6)
Upinder Singh
William A. Petri, Jr.
Plasmodium Species (Malaria)	2817	(28)
Donald J. Krogstad
Leishmania Species: Visceral (Kala-Azar), Cutaneous, and Mucosal Leishmaniasis	2831
Richard D. Pearson, Anastacio de Queiroz Sousa
Trypanosoma Species (American Trypanosomiasis, Chagas' Disease): Biology of Trypanosomes	2845	(8)
Louis V. Kirchhoff
Agents of African Trypanosomiasis (Sleeping Sickness)	2853	(5)
Louis V. Kirchoff
Toxoplasma gondii	2858	(30)
Jose G. Montoya
Jack S. Remington
Giardia lamblia	2888
David R. Hill
Trichomonas vaginalis	1894	(1005)
Michael F. Rein
Babesia	2899	(4)
Jeffrey A. Gelfand
Debra Poutsiaka
Cryptosporidium	2903	(12)
Beth L. P. Ungar
Isospora belli, Sarcocystis Species, Blastocystis hominis, and Cyclospora	2915	(5)
Jay S. Keystone
Phyllis Kozarsky
Microsporidia	2920	(14)
Rainer Weber
David A. Schwartz
Ralph T. Bryan
SECTION I. Diseases Due To Toxic Algae	2934	(3)
Human Illness Associated with Harmful Algal Blooms	2934	(3)
J. Glenn Morris, Jr.
SECTION J. Diseases Due To Helminths	2937	(34)
Introduction to Helminth Infections	2937	(1)
Adel A. F. Mahmoud
Intestinal Nematodes (Roundworms)	2938	(5)
Adel A. F. Mahmoud
Tissue Nematodes (Trichinosis, Dracunculiasis, Filariasis)	2943	(7)
David I. Grove
Trematodes (Schistosomiasis) and Other Flukes	2950	(6)
Adel A. F. Mahmoud
Cestodes (Tapeworms)	2956	(9)
Charles H. King
Visceral Larva Migrans and Other Unusual Helminth Infections	2965	(6)
Theodore E. Nash
SECTION K. Ectoparasitic Diseases	2971	(16)
Introduction to Ectoparasitic Diseases	2971	(1)
Michael Eric Mathieu
Barbara Braunstein Wilson
Lice (Pediculosis)	2972	(2)
Michael Eric Mathieu
Barbara Braunstein Wilson
Scabies	2974	(2)
Michael Eric Mathieu
Barbara Braunstein Wilson
Myiasis	2976	(3)
Michael Eric Mathieu
Barbara Braunstein Wilson
Mites (Including Chiggers)	2979	(1)
Michael Eric Mathieu
Barbara Braunstein Wilson
Ticks (Including Tick Paralysis)	2980	(3)
Michael Eric Mathieu
Barbara Braunstein Wilson
Kawasaki Syndrome	2983	(4)
Frank T. Saulsbury
PART IV Special Problems	2987	(1)
SECTION A. Nosocomial Infections	2988	(91)
Organization for Infection Control	2988	(3)
Michael B. Edmond
Richard P. Wenzel
Isolation	2991	(4)
Michael B. Edmond
Richard P. Wenzel
Disinfection, Sterilization, and Control of Hospital Waste	2995	(10)
Mussaret Zaidi
Richard P. Wenzel
Infections Due to Percutaneous Intravascular Devices	3005	(15)
David K. Henderson
Nosocomial Respiratory Infections	3020	(8)
Larry J. Strausbaugh
Nosocomial Urinary Tract Infections	3028	(11)
John W. Warren
Nosocomial Hepatitis and Other Infections Transmitted by Blood and Blood Products	3039	(13)
Kent A. Sepkowitz
Human Immunodeficiency Virus in Health Care Settings	3052	(14)
Linda A. Chiarello
Julie Louise Gerberding
Nosocomial Herpesvirus Infections	3066	(13)
David K. Henderson
SECTION B. Infections in Special Hosts	3079	(98)
Infections in the Immunocompromised Host: General Principles	3079	(11)
Ben E. De Pauw
J. Peter Donnelly
Infections in Patients with Acute Leukemia and Lymphoma	3090	(12)
Ben E. De Pauw
FrancCoise Meunier
Empirical Therapy and Prevention of Infection in the Immunocompromised Host	3102	(10)
Philip A. Pizzo
Infections in Injection Drug Users	3112	(14)
Donald P. Levine
Patricia D. Brown
Risk Factors and Approaches to Infections in Transplant Recipients	3126	(10)
J. Stephen Dummer
Monto Ho
Infections in Recipients of Blood and Marrow Transplantation	3136	(12)
Jo-Anne Van Burik
Daniel Weisdorf
Infections in Solid Organ Transplant Recipients	3148	(11)
J. Stephen Dummer
Monto Ho
Infections in Patients with Spinal Cord Injury	3159	(5)
Rabih O. Darouiche
Infections in the Elderly	3164	(5)
Kent B. Crossley
Philip K. Peterson
Infections in Asplenic Patients	3169	(8)
Larry I. Lutwick
SECTION C. Surgical and Trauma-Related Infections	3177	(30)
Postoperative Infections and Antimicrobial Prophylaxis	3177	(14)
Douglas S. Kernodle
Allen B. Kaiser
Multiple Trauma	3191	(7)
Ronald P. Rabinowitz
Anthony E. Fiore
Manjari Joshi
Ellis S. Caplan
Burns	3198	(4)
Roger W. Yurt
Bites	3202	(5)
Ellie J. C. Goldstein
SECTION D.	3207	(28)
Immunization	3207	(28)
Walter A. Orenstein
Melinda Wharton
Kenneth J. Bart
Alan R. Hinman
SECTION E. Biological Warfare	3235	(4)
Biological Warfare and Bioterrorism	3235	(4)
Joshua Lederberg
SECTION F. Zoonoses	3239	(7)
Zoonoses	3239	(7)
Arnold N. Weinberg
SECTION G. Protection of Travelers	3246	(8)
Protection of Travelers	3246	(8)
Martin S. Wolfe
SECTION H. Managed Care	3254	(4)
Health Care Reform and the Specialist in Infectious Diseases	3254	(4)
Richard P. Wenzel
SECTION I. The Internet	3258	(1)
The Infectious Diseases Physician and the Internet	3258
Edward H. Shortliffe
Lawrence M. Fagan
Victor L. Yu
Index	i