Marijuana and Madness

by Castle, David; Murray, Robin M.; D'souza, Deepak Cyril

• ISBN13: 9781107000216
• ISBN10: 1107000211
• Edition: 2nd
• Format: Hardcover
• Copyright: 2011-12-30
• Publisher: Cambridge Univ Pr

Summary

The second edition of this critically acclaimed and award-winning text provides a comprehensive overview of the psychiatry and neuroscience of Cannabis sativa (marijuana). It outlines the very latest developments in our understanding of the human cannabinoid system, and links this knowledge to clinical and epidemiological facts about the impact of cannabis on mental health. Clinically focused chapters review not only the direct psychomimetic properties of cannabis, but also the impact consumption has on the courses of evolving or established mental illnesses such as schizophrenia. Effects of cannabis on mood are reviewed, as are its effects on cognition. This new edition has been extensively updated and expanded with 10 new chapters to incorporate major new research findings. This book will be of interest to all members of the mental health team, as well as to neuroscientists, epidemiologists, public health specialists and those involved in drug and alcohol research.

Table of Contents

Foreword

Preface

Pharmacology of Cannabis and the Endocannabinoid System

The cannabinoid system from the point of view of a chemist

The function of the endocannabinoid system

How cannabis works in the brain

The Changing Face of Cannabis

The epidemiology of cannabis use: an international perspective

Is cannabis becoming more potent? Mahmoud ElSohly

Health policy and cannabis

Cannabis and the Brain

Cannabis, endocannabinoids and neurodevelopment

The impact of pubertal exposure to cannabis on the brain: a focus on animal studies

Cannabis and cognition: short and long-term effects

Does cannabis cause lasting brain damage?

Cannabis, Anxiety and Mood

Acute and subacute psychiatric effects of cannabis

The association between cannabis use and depression

Cannabis and bipolar disorder Carol Silberberg

Cannabis and Psychosis

Cannabis and psychosis proneness

Genetic factors that moderate the psychomimetic effects of cannabis

Cannabis causes positive, negative, cognitive symptoms and produces impairments in electrophysiological indices of information processing

The neural basis for the acute effects of cannabis on learning and psychosis

Cannabinoids and Schizophrenia: Aetiopathology and Treatment Implications

Does cannabis cause schizophrenia?

Postmortem studies of the brain cannabinoid system in schizophrenia

The endogenous cannabinoid system in schizophrenia

The endocannabinoid system as a target for pharmacotherapy of schizophrenia

Cannabis and its Impact on Schizophrenia

Acute effects of cannabis in established schizophrenia

Cannabis and the long-term course of schizophrenia

Motives that maintain cannabis use in schizophrenia

Treatment interventions for cannabis abuse in people with psychosis

Integration

Cannabis and mental illness: an integration

Index

Table of Contents provided by Publisher. All Rights Reserved.