Marsupial Genetics and Genomics

by Deakin, Janine E.; Waters, Paul D.; Graves, Jennifer A. Marshall

• ISBN13: 9789048190225
• ISBN10: 9048190223
• Format: Hardcover
• Copyright: 2010-07-29
• Publisher: Springer Verlag

Summary

Marsupials belong to the Class Mammalia, sharing some features with other mammals, yet they also possess many unique features. It is their differences from the more traditionally studied mammals, such as mice and humans, that is of greatest value to comparative studies. Sequencing of genomes from two distantly related marsupials, the short grey-tailed opossum from South America and the Australian tammar wallaby, has launched marsupials into the genomics era and accelerated the rate of progress in marsupial research. With the current worldwide concern for the plight of the endangered Tasmanian devil, marsupial genetics and genomics research is even more important than ever if this species is to be saved from extinction. This volume recounts some of the history of research in this field and highlights the most recent advances in the many different areas of marsupial genetics and genomics research.

Table of Contents

Marsupial Breeding
Breeding and Genetic Management of Captive Marsupial Populations	p. 5
Marsupial Chromosomes and Gene Maps
The Conserved Marsupial Karyotype: Chromosome Painting and Evolution	p. 37
Marsupial Centomeres and Telomeres: Dynamic Chromosome Domains	p. 55
Marsupial Linkage Maps	p. 75
Physical and Comparative Gene Maps in Marsupials	p. 101
Marsupial Genome Sequencing
Marsupial Sequencing Projects and Bioinformatics Challenges	p. 121
Insight into Evolution of Gene Regulation Networks from the Opossum Genome	p. 133
Marsupial Sex Chromosomes
Organization and Evolution of the Marsupial X Chromosome	p. 151
Gene Content of the Mammalian X Chromosome	p. 173
Marsupial Sex Chromosome Behaviour During Male Meiosis	p. 187
Compact but Complex - The Marsupial Y Chromosome	p. 207
Marsupial Epigenetics
The Evolution of Genomic Imprinting - A Marsupial Perspective	p. 233
Marsupial Genetics Reveals Insights into Evolution of Mammalian X Chromosome Inactivation	p. 259
Marsupial Reproductive and Developmental Genetics
Molecular Regulation of Marsupial Reproduction and Development	p. 285
Marsupial Milk - Identifying Signals for Regulating Mammary Function and Development of the Young	p. 317
Marsupial Immune Genes
The Marsupial Major Histocompatibility Complex	p. 339
Marsupial Immunoglobulin and T Cell Receptor Genomics	p. 357
Use of Genomic Information to Gain Insights into Immune Function in Marsupials: A Review of Divergent Immune Genes	p. 381
Marsupial Genes and Gene Evolution
Visual Pigments and Colour Vision in Marsupials and Monotremes	p. 403
The Evolutionary History of Globin Genes: Insights from Marsupials and Monotremes	p. 415
The Olfactory Receptor Gene Family of Marsupials	p. 435
Marsupial Conservation Genetics
Marsupial Population and Conservation Genetics	p. 461
Devil Facial Tumour Disease (DFTD): Using Genetics and Genomics to Investigate Infectious Disease in an Endangered Marsupial	p. 499
Index	p. 517
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