Medical Microbiology : With Student Consult Online Access

by Goering, Richard

• ISBN13: 9780323044752
• ISBN10: 0323044751
• Edition: 4th
• Format: Paperback
• Copyright: 2007-10-01
• Publisher: MOSBY-YEAR BOOK INC

Summary

MIMS' MEDICAL MICROBIOLOGY offers thorough and up-to-date coverage of microbiology and basic immunology, through a clinically relevant, systems-based approach. The textbook emphasises the microbiology of the agents causing disease, and the diseases affecting individual organ systems. Through thorough cross referencing, the reader can easily find what they need, whether seeking information from a systems or a microbe perspective. Nearly 500 illustrations support the text, and summary introductory and summary key facts boxes strengthen the clarity and usefulness of the text. Ten animations on STUDENT CONSULT offer a visually rich way to approach this subject area. Systems-based approach to microbiology reflects integrated and case-based teaching Stresses the role of the immune system in infectious disease, in line with the move towards integrated, systems-based teaching (where for example diseases like meningitis are taught as part of a Nervous system module) Chapter Introduction boxes (now revised to be in bullet points), Summary Headings throughout each chapter and Key Facts boxes at the end of each chapter allow easy access to key concepts, and valuable review tools Extensively cross-referenced Pathogen Review section means the reader can navigate the text either through a systems-based or a pathogen-based path, as they choose Online animations provide visual support in explaining key information Wide range of questions available on www.studentconsult.com

Table of Contents

Microbes as parasites

The varieties of microbes

Living inside or outside cells

Systems of classification

The bacteria

Structure

Nutrition

Growth and division

Gene expression

Extrachromosomal elements

Mutation and gene transfer

Survival under adverse conditions

The genomics of medically important bacteria

The viruses

Infection of host cells

Replication

Outcome of viral infection

Major groups of viruses

The fungi

Major groups of disease-causing fungi

The protozoa

The helminths and arthropods

The helminths

The arthropods

Prions

Rogue protein pathogenesis

Development and transmission of prion diseases

Medical problems posed by prion disease

The hostparasite relationship

The normal flora

Symbiotic associations

The characteristics of parasitism

The evolution of parasitism

The innate defenses of the body

Defense against entry into the body

Defenses once the microorganism penetrates the body

Adaptive responses provide a quantum leap in effective defense

The role of antibodies

The role of T lymphocytes

Extracellular attack on large infectious agents

Local defenses at mucosal surfaces

The cellular basis of adaptive immune responses

B and T cell receptors

Clonal expansion of lymphocytes

The role of memory cells

Stimulation of lymphocytes

Cytokines

Regulatory mechanisms

Tolerance mechanisms

Background to the infectious diseases

Hostparasite relationships

Causes of infectious diseases

The biologic response gradient

Entry, exit and transmission

Sites of entry

Exit and transmission

Types of transmission between humans

Transmission from animals

Immune defenses in action

Complement

Acute phase proteins and pattern recognition receptors

Fever

Natural killer cells

Phagocytosis

Cytokines

Antibody-mediated immunity

Cell-medited immunity

Recovery from infection

Spread and replication

Features of surface and systemic infections

Mechanisms of spread through the body

Genetic determinants of spread and replication

Other factors affecting spread and replication

Parasite survival strategies and persistent infections

Parasite survival strategies

Concealment of antigens

Antigenic variation

Immunosuppression

Persistent infections

Pathologic consequences of infection

Pathology caused directly by the microorganism

Pathologic activation of natural immune mechanisms

Pathologic consequences of the immune response

Skin rashes

Viruses and cancer

Introduction to

The Clinical Manifestations of Infection

Upper respiratory tract infections

The common cold

Pharyngitis and tonsillitis

Parotitis

Otitis and sinusitis

Acute epiglottitis

Oral cavity infections

Laryngitis and tracheitis

Diphtheria

Lower respiratory tract infections

Acute infections

Chronic infections

Parasitic infections

Urinary tract infections

Acquisition and etiology

Pathogenesis

Clinical features and complications

Laboratory diagnosis

Treatment

Prevention

Sexually transmitted diseases

STDs and sexual behavior

Syphilis

Gonorrhea

Chlamydial infection

Other causes of inguinal lymphadenopathy

Mycoplasmas and non-gonococcal urethritis

Other causes of vaginitis and urethritis

Genital herpes

Human papillomavirus infection

Human immunodeficiency virus

Opportunistic STDs

Arthropod infesta

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