Medical Pharmacology and Therapeutics; with STUDENT CONSULT Access

by Waller, Renwick & Hillier

• ISBN13: 9780702027543
• ISBN10: 0702027545
• Edition: 2nd
• Format: Paperback
• Copyright: 2005-08-03
• Publisher: Saunders Ltd.

Summary

This book covers the whole gamut of pharmacology from basic science pharmacology and pathophysiology, through clinical pharmacology to therapeutics. This integrative approach is in line with the new medical curricula. The first section covers the basic principles, followed by the bulk of the book organized by body systems. The book ends with sections on toxicity and prescribing practice. Each chapter ends with case histories, multiple choice questions and a tabular presentation of all common drugs within a particular class. The new edition now comes with STUDENT CONSULT access, which allows users to integrate additional vital information. The level of detail closely matches the needs of medical students and the current medical curriculum. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Includes access to www.studentconsult.com, where readers will find the complete text and illustrations of the book are online-fully searchable · "Integration Links" to bonus content in other STUDENT CONSULT titles · content clipping for handheld devices · an interactive community center with a wealth of additional resources · and more.

Table of Contents

Preface	vii
Acknowledgements	viii
Drug dosages and nomenclature	ix
SECTION 1 General principles
Sites and mechanisms of drug action	3	(14)
Pharmacokinetics	17	(32)
Drug discovery, evaluation and safety	49	(8)
The nervous system, neurotransmission and the peripheral autonomic nervous system	57	(30)
SECTION 2 The cardiovascular system
Ischaemic heart disease	87	(16)
Hypertension	103	(20)
Heart failure	123	(12)
Cardiac arrhythmias	135	(18)
Cerebrovascular disease and dementia	153	(8)
Peripheral vascular disease	161	(6)
Haemostasis	167	(20)
SECTION 3 The respiratory system
Asthma and chronic obstructive pulmonary disease	187	(16)
Respiratory disorders: cough, respiratory stimulants, cystic fibrosis and neonatal respiratory distress syndrome	203	(8)
SECTION 4 The renal system
Diuretics	211	(12)
Disorders of micturition	223	(8)
Erectile dysfunction	231	(8)
SECTION 5 The nervous system
General anaesthetics	239	(10)
Local anaesthetics	249	(6)
Opioid analgesics and the management of pain	255	(14)
Anxiolytics, sedatives and hypnotics	269	(10)
The major psychotic disorders: schizophrenia and mania	279	(12)
Depression	291	(14)
Epilepsy	305	(14)
Extrapyramidal movement disorders and spasticity	319	(12)
Other neurological disorders: multiple sclerosis, motor neuron disease and Guillain--Barre syndrome	331	(4)
Migraine	335	(10)
SECTION 6 The musculoskeletal system
The neuromuscular junction and neuromuscular blockade	345	(8)
Myasthenia gravis	353	(4)
Non-steroidal anti-inflammatory drugs	357	(12)
Rheumatoid arthritis, other inflammatory arthritides and osteoarthritis	369	(10)
Hyperuricaemia and gout	379	(8)
SECTION 7 The gastrointestinal system
Nausea and vomiting	387	(10)
Dyspepsia and peptic ulcer disease	397	(12)
Inflammatory bowel disease	409	(6)
Constipation, diarrhoea and irritable bowel syndrome	415	(8)
Liver disease	423	(8)
Obesity	431	(6)
SECTION 8 The immune system
The immune response and immunosuppressant drugs	437	(10)
Antihistamines and allergic disease	447	(10)
SECTION 9 The endocrine system and metabolism
Diabetes mellitus	457	(14)
The thyroid and control of metabolic rate	471	(6)
Calcium metabolism and metabolic bone disease	477	(8)
Pituitary and hypothalamic hormones	485	(12)
Corticosteroids (glucocorticoids and mineralocorticoids)	497	(10)
Female reproduction	507	(18)
Androgens and anabolic steroids	525	(6)
Anaemia and haematopoietic colony-stimulating factors	531	(10)
Lipid disorders	541	(14)
SECTION 10 The skin and eyes
Skin disorders	555	(10)
The eye	565	(12)
SECTION 11 Chemotherapy
Chemotherapy of infections	577	(58)
Chemotherapy of malignancy	635	(30)
SECTION 12 General features: toxicity and prescribing
Drug toxicity and overdose	665	(14)
Drug abuse and dependence	679	(12)
Prescribing, adherence and information about medicines	691	(4)
Drug therapy in special situations	695	(8)
Self-assessment answers	703	(46)
Index	749