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Introduction | p. ix |
Editor | p. xv |
Contributors | p. xvii |
Evolutionary Tools in Metabolic Engineering | |
Evolutionary Engineering of Industrially Important Microbial Phenotypes | p. 1 |
Improving Protein Functions by Directed Evolution | p. 2 |
Engineering DNA and RNA Regulatory Regions through Random Mutagenesis and Screening | p. 3 |
Evolving Pathways and Genomes for the Production of Natural and Novel Compounds | p. 4 |
Models Predicting Optimized Strategies for Protein Evolution | p. 5 |
Gene Expression Tools for Metabolic Pathway Engineering | |
Low-Copy Number Plasmids as Artificial Chromosomes | p. 6 |
Chromosomal Engineering Strategies | p. 7 |
Regulating Gene Expression through Engineered RNA Technologies | p. 8 |
Tools Designed to Regulate Translational Efficiency | p. 9 |
Metabolic Engineering of the Secretory Processing Pathway in Eukaryotes | p. 10 |
Engineering Multifunctional Enzyme Systems for Optimized Metabolite Transfer between Sequential Conversion Steps | p. 11 |
Practical Pathway Engineering-Demonstration in Integrating Tools | p. 12 |
Application of Emerging Technologies to Metabolic Engineering | |
Genome-Wide Technologies: DNA Microarrays, Phenotypic Microarrays, and Proteomics | p. 13 |
Monitoring and Measuring the Metabolome | p. 14 |
Future Prospects in Metabolic Engineering | |
Systems Biology, Genome-Scale Models, and Metabolic Engineering | p. 15 |
Cell-Free Systems for Metabolic Engineering | p. 16 |
In Silico Models for Metabolic Systems Engineering | p. 17 |
Tools for Experimentally Determining Flux through Pathways | |
GC-MS for Metabolic Flux Analysis | p. 18 |
Tools for Measuring Intermediate and Product Formation | p. 19 |
Use of AEX-HPLC-ESI-MS for 13C-Labeling Based Metabolic Flux Analysis in Saccharomyces cerevisiae and Penicillium chrysogenum | p. 20 |
Future Applications of Metabolic Engineering | |
Energy and Cofactor Issues in Fermentation and Oxyfunctionalization Processes | p. 21 |
Microbial Biosynthesis of Fine Chemicals: An Emerging Technology | p. 22 |
Applications of Metabolic Engineering for Natural Drug Discovery | p. 23 |
Metabolic Engineering for Alternative Fuels | p. 24 |
Index | p. I |
Table of Contents provided by Ingram. All Rights Reserved. |
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The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.