Metagenomics of the Human Body

by Nelson, Karen E., Ph.D.; Peterson, Jane L.; Garges, Susan

• ISBN13: 9781441970886
• ISBN10: 1441970886
• Format: Hardcover
• Copyright: 2010-11-17
• Publisher: Springer Verlag

Summary

The book brings a completely different perspective than available books by combining the information gained from the human genome with that derived from parallel metagenomic studies, and new results from investigating the effects of these microbes on the host immune system. Although there are a number of books that focus on the human genome that are currently available, there are no books that bring to the forefront the mix of the human genome and the genomes and metagenomes of the microbial species that live within and on us.

Author Biography

Dr. Karen E. Nelson is the Director of the Rockville Campus of the J. Craig Venter Institute (JCVI) where she has been for the past 14 years. She was formerly the Director of Human Microbiology and Metagenomics in the Department of Human Genomic Medicine at the JCVI. She has authored or co-authored over 100 publications, and is currently Editor-in-Chief of the Springer journal Microbial Ecology. She is also a standing member of the NRC Committee on Biodefense, a member of the American Society for Microbiology (ASM) Communications Committee and a Fellow of the ASM.

Table of Contents

The Human Genome, Microbiomes, and Disease	p. 1
Host Genotype and the Effect on Microbial Communities	p. 15
The Human Microbiome and Host-Pathogen Interactions	p. 43
The Human Virome	p. 63
Selection and Sequencing of Strains as References for Human Microbiome Studies	p. 79
The Human Vaginal Microbiome	p. 91
The Human Lung Microbiome	p. 117
The Human Skin Microbiome in Health and Skin Diseases	p. 145
The Human Oral Metagenome	p. 165
The Human and His Microbiome Risk Factors for Infections	p. 175
Infectogenomics: Aspect of Host Responses to Microbes in Digestive Tract	p. 217
Autoimmune Disease and the Human Metagenome	p. 231
Metagenomic Applications and the Potential for Understanding Chronic Liver Disease	p. 277
Symbiotic Gut Microbiota and the Modulation of Human Metabolic Phenotypes	p. 297
MetaHIT: The European Union Project on Metagenomics of the Human Intestinal Tract	p. 307
Implications of Human Microbiome Research for the Developing World	p. 317
Index	p. 337
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