Methods in Chemosensory Research

by Simon; Sidney A.

• ISBN13: 9780849323294
• ISBN10: 0849323290
• Edition: 1st
• Format: Hardcover
• Copyright: 2001-09-26
• Publisher: CRC Press

Summary

Written by world experts in the field of neuronal chemoreception, Methods in Chemosensory Research describes new molecular, electrophysiological, genetic, behavioral, psychophysical, and imaging techniques that have recently been adapted to investigate the basic neuronal mechanisms underlying chemoreception: taste, olfaction and chemical-induced irritation. This unique book includes a wide variety of new and innovative imaging methods, electrophysiological methods, methods to investigate development, and various aspects of behavioral testing. Covering the entire spectrum of chemoreception, each section not only describes what information can be obtained by using each method, but also shows how to apply each method to obtain reliable results. The book presents a comprehensive view of how the brain uses information about chemical stimuli that interact with receptors in the nose and tongue. Methods in Chemosensory Research gives you the new tools to learn how chemicals affect activity from the genetic to the behavioral levels.

Table of Contents

Behavioral Studies

Psychophysical Measurement of Oral Chemesthesis

Behavioral Methods in Olfactory Research with Rodents

Molecular and Cell Biology of Taste and Olfaction

Recordings from Vertebrate Olfactory Receptor Neurons: From Isolated Cells to Intact Epithelial Preparations

Recordings from Olfactory Receptor Neurons in the Rat in Vivo

Voltage-Sensitive and Calcium-Sensitive Dye Imaging of Activity in the Olfactory Bulb: Presynaptic Inhibition, Maps of Receptor Cell Input, and Oscillations

Gustatory System Development: New Experimental Approaches in Amphibian and Mammalian Embryos

Mammalian Taste Receptors

Researching Isolated Taste Receptor Cells: Deciphering Transduction Cascades with Patch-Clamp and Calcium: Imaging Techniques

Rapid Kinetic Measurements in Chemosensory Systems

Electrophysiological Recordings of Mammalian Taste

Higher-Order Studies in Taste and Olfaction

Activation of Neurons in the Trigeminal Subnucleus Caudalis (Vc) by Irritant Chemical Stimulation: Extracellular Single- Unit Recording and c-fos Immunohistochemical Methods

Methodological Considerations for Electrophysiological Recording and Analysis of Taste-Responsive Neurons in the Brainstem of the Rat

Electrophysiological Analysis of Olfactory Coding in the CNS

Electrophysiological Studies of Gustation in Awake Rats

Recording from Single Neurons in the Primary Taste Cortex of the Alert Macaque

Olfactory Learning and the Neurophysiological Study of Rat Prefrontal Function

Olfactory Event-Related Potentials

Application of Functional MRI in Olfactory Studies

Functional Imaging of Olfactory Activation in the Human Brain