Modern Microbial Genetics, 2nd Edition

by Editor: Uldis N. Streips (Department of Microbiology and Immunology, School of Medicine, University of Louisville, Louisville, KY 40292, USA); Editor: Ronald E. Yasbin (Program in Molecular Biology, University of Texas at Dallas, Richardson, TX 750

• ISBN13: 9780471386650
• ISBN10: 0471386650
• Edition: 2nd
• Format: Hardcover
• Copyright: 2002-02-01
• Publisher: Wiley-Liss

Summary

In accordance with its predecessor, the completely revised and expanded Second Edition of Modern Microbial Genetics focuses on how bacteria and bacteriophage arrange and rearrange their genetic material through mutation, evolution, and genetic exchange to take optimal advantage of their environment. The text is divided into three sections: DNA Metabolism, Genetic Response, and Genetic Exchange. The first addresses how DNA replicates, repairs itself, and recombines, as well as how it may be manipulated. The second section is devoted to how microorganisms interact with their environment, including chapters on sporulation and stress shock, and the final section contains the latest information on classic exchange mechanisms such as transformation and conjugation. Chapters include: * Gene Expression and Its Regulation * Single-Stranded DNA Phages * Genetic Tools for Dissecting Motility and Development of Myxococcus xanthus * Molecular Mechanism of Quorum Sensing * Transduction in Gram-Negative Bacteria * Genetic Approaches in Bacteria with No Natural Genetic Systems The editors also cultivate an attention to global regulatory systems throughout the book, elucidating how certain genes and operons in bacteria, defined as regulons, network and cooperate to suit the needs of the bacterial cell. With clear appreciation for the impact of molecular genomics, this completely revised and updated edition proves that Modern Microbial Genetics remains the benchmark text in its field.

Table of Contents

Preface	vii
Preface to the First Edition	ix
Introduction	xi
Contributors	xiii
Section 1: DNA METABOLISM	1	(258)
Prokaryotic DNA Replication	3	(24)
William Firshein
DNA Repair Mechanisms and Mutagenesis	27	(20)
Ronald E. Yasbin
Gene Expression and Its Regulation	47	(38)
John D. Helmann
Bacteriophage Genetics	85	(42)
Burton S. Guttman
Elizabeth M. Kutter
Bacteriophage λ and Its Relatives	127	(18)
Roger W. Hendrix
Single-Stranded DNA Phages	145	(32)
J. Eugene LeClerc
Restriction-Modification Systems	177	(50)
Robert M. Blumenthal
Xiaodong Cheng
Recombination	227	(16)
Stephen D. Levene
Kenneth E. Huffman
Molecular Applications	243	(16)
Thomas Geoghegan
Section 2: GENETIC RESPONSE	259	(126)
Genetics of Quorum Sensing Circuitry in Pseudomonas aeruginosa: Implications for Control of Pathogenesis, Biofilm Formation, and Antibiotic/Biocide Resistance	261	(12)
Daniel J. Hassett
Urs A. Ochsner
Teresa de Kievit
Barbara H. Iglewski
Luciano Passador
Thomas S. Livinghouse
Timothy R. McDermott
John J. Rowe
Jeffrey A. Whitsett
Endospore Formation in Bacillus subtilis: An Example of Cell Differentiation by a Bacterium	273	(8)
Charles P. Moran Jr.
Stress Shock	281	(8)
Uldis N. Streips
Genetic Tools for Dissecting Motility and Development of Myxococcus xanthus	289	(34)
Patricia L. Hartzell
Agrobacterium Genetics	323	(26)
Walt Ream
Two-Component Regulation	349	(12)
Kenneth W. Bayles
David F. Fujimoto
Molecular Mechanisms of Quorum Sensing	361	(24)
Clay Fuqua
Matthew R. Parsek
Section 3: GENETIC EXCHANGE	385	(218)
Bacterial Transposons---An Increasingly Diverse Group of Elements	387	(42)
Gabrielle Whittle
Abigail A. Salyers
Transformation	429	(34)
Uldis N. Streips
Conjugation	463	(44)
Ronald D. Porter
The Subcellular Entities a.k.a. Plasmids	507	(54)
Michael H. Perlin
Transduction in Gram-Negative Bacteria	561	(20)
George M. Weinstock
Genetic Approaches in Bacteria with No Natural Genetic Systems	581	(22)
Carolyn A. Haller
Thomas J. DiChristina
Index	603