Molecular Biology of the Cell

by Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Raff, Martin; Roberts, Keith; Walter, Peter

• ISBN13: 9780815332183
• ISBN10: 0815332181
• Edition: 4th
• Format: Hardcover
• Copyright: 2002-03-01
• Publisher: Garland

Summary

Molecular Biology of the Cellis the classic in-depth text reference in cell biology. By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology.Molecular Biology of the Cellsets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clearand concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice.

Table of Contents

Special Features	ix
List of Topics	xi
Acknowledgments	xxix
A Note to the Reader	xxxiii
PART I INTRODUCTION TO THE CELL
Cells and Genomes	3	(44)
Cell Chemistry and Biosynthesis	47	(82)
Proteins	129	(62)
PART II BASIC GENETIC MECHANISMS
DNA and Chromosomes	191	(44)
DNA Replication, Repair, and Recombination	235	(64)
How Cells Read the Genome: From DNA to Protein	299	(76)
Control of Gene Expression	375	(94)
PART III METHODS
Manipulating Proteins, DNA, and RNA	469	(78)
Visualizing Cells	547	(36)
PART IV INTERNAL ORGANIZATION OF THE CELL
Membrane Structure	583	(32)
Membrane Transport of Small Molecules and the Electrical Properties of Membranes	615	(44)
Intracellular Compartments and Protein Sorting	659	(52)
Intracellular Vesicular Traffic	711	(56)
Energy Conversion: Mitochondria and Chloroplasts	767	(64)
Cell Communication	831	(76)
The Cytoskeleton	907	(76)
The Cell Cycle and Programmed Cell Death	983	(44)
The Mechanics of Cell Division	1027	(38)
PART V CELLS IN THEIR SOCIAL CONTEXT
Cell Junctions, Cell Adhesion, and the Extracellular Matrix	1065	(62)
Germ Cells and Fertilization	1127	(30)
Development of Multicellular Organisms	1157	(102)
Histology: The Lives and Deaths of Cells in Tissues	1259	(54)
Cancer	1313	(50)
The Adaptive Immune System	1363	(60)
Pathogens, Infection, and Innate Immunity	1423
Glossary	G-1
Index	I-1
Tables: The Genetic Code, Amino Acids	T-1