Molecular Diagnostics: Fundamentals, Methods and Clinical Applications

by Buckingham, Lela

• ISBN13: 9780803626775
• ISBN10: 0803626770
• Edition: 2nd
• Format: Paperback
• Copyright: 2011-12-15
• Publisher: F A Davis Co

Summary

"I would like to say that once published the second edition of 'Molecular Diagnostics' would be a significant addition to the advancing science of molecular diagnostics. It would serve the multi-purpose of a textbook and a reference guide as well as troubleshooter. I can imagine it would be equally admired by the educator, student and scientist." Hamida Nusrat, PhDLecturer, CLS Internship ProgramSan Francisco State University, San Ramon, CAThis exceptional resource introduces the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to professional practice in today's laboratories. With a focus on the application of molecular concepts to diagnosis diseases, the 2nd Edition reflects the many advances in this rapidly developing field.Inside, you'll find in-depth explanations of the principles of molecular-based assays as well as reference material and trouble-shooting tips for the laboratory. Discussions of general diagnostic procedures reflect the continuing emergence of new diagnostic technologies to prepare you to meet the challenges of the future.

Table of Contents

Fundamentals of Nucleic Acid Biochemistry: An Overview DNA RNA Proteins Common Techniques in Molecular Biology Nucleic Acid Extraction Methods Resolution and Detection of Nucleic Acids Analysis and Characterization of Nucleic Acids and Proteins Nucleic Acid Amplification Chromosomal Structure and Chromosomal Mutations Gene Mutations DNA Sequencing Techniques in the Clinical Lab DNA Polymorphisms and Human Identification Detection and Identification of Microorganisms Molecular Detection of Inherited Diseases Molecular Oncology DNA-Based Tissue Typing Quality Assurance and Quality Control in the Molecular Laboratory Appendix